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Adenoid Cystic Carcinoma of Bartholin's Gland: A Case Report with Emphasis on Surgical Management.
Am J Case Rep. 2022 Mar 09; 23:e935707.AJ

Abstract

BACKGROUND Adenoid cystic carcinomas of Bartholin's gland are rare among gynecological malignancies, accounting for 0.1% to 7% of vulvar carcinomas and 0.001% of all female genital tract malignancies. There are no specific guidelines regarding treatment recommendations; therefore, they are commonly treated like vulvar cancer. CASE REPORT We present the case of a 42-year-old premenopausal woman with an adenoid cystic carcinoma of Bartholin's gland diagnosed upon biopsy of a palpable, predominantly vaginally located mass causing foreign-body sensation, vaginal pain, and extreme dyspareunia. The adenoid cystic carcinoma of Bartholin's gland was treated by radical resection in an extensive interdisciplinary surgical approach including bilateral inguinal lymph node dissection, partial posterior colpectomy, amputation of the rectum, and creation of a descendostomy, as well as reconstruction of the vagina and defect coverage using flap plastic. CONCLUSIONS With the presentation of this case, we propose a possible therapeutic approach to adenoid cystic carcinomas of Bartholin's gland with emphasis on surgical management. Especially in young patients, we recommend primary radical surgery with the objective to obtain negative resection margins. However, additional data on the adenoid cystic carcinoma of Bartholin's gland is needed to better understand its biological behavior and thus optimize and standardize treatment. The role of systematic inguinal-femoral lymphadenectomy and adjuvant and neoadjuvant treatment modalities need further evaluation.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Lucerne Cantonal Hospital, Lucerne, Switzerland.Department of Obstetrics and Gynecology, Lucerne Cantonal Hospital, Lucerne, Switzerland.Department of Obstetrics and Gynecology, Lucerne Cantonal Hospital, Lucerne, Switzerland.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

35260546

Citation

Verta, Stephanie, et al. "Adenoid Cystic Carcinoma of Bartholin's Gland: a Case Report With Emphasis On Surgical Management." The American Journal of Case Reports, vol. 23, 2022, pp. e935707.
Verta S, Christmann C, Brambs CE. Adenoid Cystic Carcinoma of Bartholin's Gland: A Case Report with Emphasis on Surgical Management. Am J Case Rep. 2022;23:e935707.
Verta, S., Christmann, C., & Brambs, C. E. (2022). Adenoid Cystic Carcinoma of Bartholin's Gland: A Case Report with Emphasis on Surgical Management. The American Journal of Case Reports, 23, e935707. https://doi.org/10.12659/AJCR.935707
Verta S, Christmann C, Brambs CE. Adenoid Cystic Carcinoma of Bartholin's Gland: a Case Report With Emphasis On Surgical Management. Am J Case Rep. 2022 Mar 9;23:e935707. PubMed PMID: 35260546.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adenoid Cystic Carcinoma of Bartholin's Gland: A Case Report with Emphasis on Surgical Management. AU - Verta,Stephanie, AU - Christmann,Corina, AU - Brambs,Christine E, Y1 - 2022/03/09/ PY - 2022/3/9/entrez PY - 2022/3/10/pubmed PY - 2022/3/11/medline SP - e935707 EP - e935707 JF - The American journal of case reports JO - Am J Case Rep VL - 23 N2 - BACKGROUND Adenoid cystic carcinomas of Bartholin's gland are rare among gynecological malignancies, accounting for 0.1% to 7% of vulvar carcinomas and 0.001% of all female genital tract malignancies. There are no specific guidelines regarding treatment recommendations; therefore, they are commonly treated like vulvar cancer. CASE REPORT We present the case of a 42-year-old premenopausal woman with an adenoid cystic carcinoma of Bartholin's gland diagnosed upon biopsy of a palpable, predominantly vaginally located mass causing foreign-body sensation, vaginal pain, and extreme dyspareunia. The adenoid cystic carcinoma of Bartholin's gland was treated by radical resection in an extensive interdisciplinary surgical approach including bilateral inguinal lymph node dissection, partial posterior colpectomy, amputation of the rectum, and creation of a descendostomy, as well as reconstruction of the vagina and defect coverage using flap plastic. CONCLUSIONS With the presentation of this case, we propose a possible therapeutic approach to adenoid cystic carcinomas of Bartholin's gland with emphasis on surgical management. Especially in young patients, we recommend primary radical surgery with the objective to obtain negative resection margins. However, additional data on the adenoid cystic carcinoma of Bartholin's gland is needed to better understand its biological behavior and thus optimize and standardize treatment. The role of systematic inguinal-femoral lymphadenectomy and adjuvant and neoadjuvant treatment modalities need further evaluation. SN - 1941-5923 UR - https://www.unboundmedicine.com/medline/citation/35260546/Adenoid_Cystic_Carcinoma_of_Bartholin's_Gland:_A_Case_Report_with_Emphasis_on_Surgical_Management_ L2 - https://www.amjcaserep.com/download/index/idArt/935707 DB - PRIME DP - Unbound Medicine ER -