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Growth of the ICRC bacilli in the foot-pad of mice.
Lepr India. 1978 Apr; 50(2):144-55.LI

Abstract

The ICRC bacilli are acid-fast bacilli cultivated from M. leprae isolates of lepromatous tissue. The ICRC bacilli from C-44 in the conditioned medium were subjected to foot-pad test, in both normal and T/900r mice. The bacilli exhibits a limited multiplication in normal mice while a continuous growth in T/900r mice. The maximum yield for normal and T/900r mice was 10(7) and 10(9)/foot-pad, respectively. The infiltration of voluntary muscle tissue as the main localization site was common for both normal and T/900r mice with evidence of dissemination in the latter. The spread of AFB to sciatic nerve, induction of liver granuloma and the foot-drop was observed only in T/900r mice. These experiments show that the growth of ICRC bacilli in mouse foot-pad is very similar to that of M. leprae confirming a test for identification.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

353383

Citation

Bapat, C V., and M S. Modak. "Growth of the ICRC Bacilli in the Foot-pad of Mice." Leprosy in India, vol. 50, no. 2, 1978, pp. 144-55.
Bapat CV, Modak MS. Growth of the ICRC bacilli in the foot-pad of mice. Lepr India. 1978;50(2):144-55.
Bapat, C. V., & Modak, M. S. (1978). Growth of the ICRC bacilli in the foot-pad of mice. Leprosy in India, 50(2), 144-55.
Bapat CV, Modak MS. Growth of the ICRC Bacilli in the Foot-pad of Mice. Lepr India. 1978;50(2):144-55. PubMed PMID: 353383.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Growth of the ICRC bacilli in the foot-pad of mice. AU - Bapat,C V, AU - Modak,M S, PY - 1978/4/1/pubmed PY - 1978/4/1/medline PY - 1978/4/1/entrez SP - 144 EP - 55 JF - Leprosy in India JO - Lepr India VL - 50 IS - 2 N2 - The ICRC bacilli are acid-fast bacilli cultivated from M. leprae isolates of lepromatous tissue. The ICRC bacilli from C-44 in the conditioned medium were subjected to foot-pad test, in both normal and T/900r mice. The bacilli exhibits a limited multiplication in normal mice while a continuous growth in T/900r mice. The maximum yield for normal and T/900r mice was 10(7) and 10(9)/foot-pad, respectively. The infiltration of voluntary muscle tissue as the main localization site was common for both normal and T/900r mice with evidence of dissemination in the latter. The spread of AFB to sciatic nerve, induction of liver granuloma and the foot-drop was observed only in T/900r mice. These experiments show that the growth of ICRC bacilli in mouse foot-pad is very similar to that of M. leprae confirming a test for identification. SN - 0024-1024 UR - https://www.unboundmedicine.com/medline/citation/353383/Growth_of_the_ICRC_bacilli_in_the_foot_pad_of_mice_ L2 - https://medlineplus.gov/foothealth.html DB - PRIME DP - Unbound Medicine ER -
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