Tags

Type your tag names separated by a space and hit enter

Evaluation of RapidSTAT®, DrugWipe® 6S, DrugScreen® 5TK and DrugScreen® 7TR for on-site drug testing in German police roadside traffic patrol.
Drug Test Anal. 2022 Aug; 14(8):1407-1416.DT

Abstract

Driving under the influence of drugs (DUID) remains a subject of concern worldwide, and its increasing trend is likely to continue. Therefore, there is a constant need for reliable on-site drug tests to identify drugged drivers during roadside patrols. Performance and reliability of four on-site drug tests were evaluated among a high number of DUID cases in Germany. Results of oral fluid (OF) (RapidSTAT® and DrugWipe® 6S) and urine (DrugScreen® 5TK and 7TR) test devices were compared with corresponding serum/plasma results obtained by confirmation analyses in consideration of recommended analytical limits for substances pertaining the annex of the German Road Traffic Code ('Straβenverkehrsgesetz', StVG) s. 24a (2). Overall, the screening devices performed well for individual drugs; however, none of the test devices assessed in this study fulfilled the ROSITA-1 criteria (sensitivity, specificity ≥ 90% and accuracy ≥ 95%) for all substances. Our data demonstrated that both urine tests showed high sensitivities for most compounds. DrugWipe® 6S (94%) and RapidSTAT® (93%) revealed high sensitivities, especially for amphetamine screening. Poor specificities (<90%) and accuracies (<95%) were observed for all tests except for low-prevalent substances (e.g., opiates). For drug testing in OF, Δ9 -tetrahydrocannabinol (THC) still seems to be a compound of concern due to poor sensitivity (RapidSTAT®, 77%; DrugWipe® 6S, 85%), although the results indicate improvements compared with previously reported data. Although the obtained data indicate reliable detection for some substances, deployment of trained police officers is inevitable to identify DUID suspects by signs of recent use and recognising impairment.

Authors+Show Affiliations

Institute of Forensic Medicine, Forensic Toxicology, University Hospital Bonn, Bonn, Germany.North-Rhine Westphalia Police Force Central Support Services Bureau, Duisburg, Germany.Institute of Forensic Medicine, Forensic Toxicology, University Hospital Bonn, Bonn, Germany.Institute of Forensic Medicine, Forensic Toxicology, University Hospital Bonn, Bonn, Germany.Institute of Forensic Medicine, Forensic Toxicology, University Hospital Bonn, Bonn, Germany.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35343088

Citation

Liut, Jennifer, et al. "Evaluation of RapidSTAT®, DrugWipe® 6S, DrugScreen® 5TK and DrugScreen® 7TR for On-site Drug Testing in German Police Roadside Traffic Patrol." Drug Testing and Analysis, vol. 14, no. 8, 2022, pp. 1407-1416.
Liut J, Bott U, Madea B, et al. Evaluation of RapidSTAT®, DrugWipe® 6S, DrugScreen® 5TK and DrugScreen® 7TR for on-site drug testing in German police roadside traffic patrol. Drug Test Anal. 2022;14(8):1407-1416.
Liut, J., Bott, U., Madea, B., Krämer, M., & Maas, A. (2022). Evaluation of RapidSTAT®, DrugWipe® 6S, DrugScreen® 5TK and DrugScreen® 7TR for on-site drug testing in German police roadside traffic patrol. Drug Testing and Analysis, 14(8), 1407-1416. https://doi.org/10.1002/dta.3262
Liut J, et al. Evaluation of RapidSTAT®, DrugWipe® 6S, DrugScreen® 5TK and DrugScreen® 7TR for On-site Drug Testing in German Police Roadside Traffic Patrol. Drug Test Anal. 2022;14(8):1407-1416. PubMed PMID: 35343088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of RapidSTAT®, DrugWipe® 6S, DrugScreen® 5TK and DrugScreen® 7TR for on-site drug testing in German police roadside traffic patrol. AU - Liut,Jennifer, AU - Bott,Ulrich, AU - Madea,Burkhard, AU - Krämer,Michael, AU - Maas,Alexandra, Y1 - 2022/04/01/ PY - 2022/03/22/revised PY - 2021/11/11/received PY - 2022/03/24/accepted PY - 2022/3/29/pubmed PY - 2022/8/9/medline PY - 2022/3/28/entrez KW - driving under the influence of drugs (DUID) KW - oral fluid KW - roadside drug testing KW - serum/plasma KW - urine SP - 1407 EP - 1416 JF - Drug testing and analysis JO - Drug Test Anal VL - 14 IS - 8 N2 - Driving under the influence of drugs (DUID) remains a subject of concern worldwide, and its increasing trend is likely to continue. Therefore, there is a constant need for reliable on-site drug tests to identify drugged drivers during roadside patrols. Performance and reliability of four on-site drug tests were evaluated among a high number of DUID cases in Germany. Results of oral fluid (OF) (RapidSTAT® and DrugWipe® 6S) and urine (DrugScreen® 5TK and 7TR) test devices were compared with corresponding serum/plasma results obtained by confirmation analyses in consideration of recommended analytical limits for substances pertaining the annex of the German Road Traffic Code ('Straβenverkehrsgesetz', StVG) s. 24a (2). Overall, the screening devices performed well for individual drugs; however, none of the test devices assessed in this study fulfilled the ROSITA-1 criteria (sensitivity, specificity ≥ 90% and accuracy ≥ 95%) for all substances. Our data demonstrated that both urine tests showed high sensitivities for most compounds. DrugWipe® 6S (94%) and RapidSTAT® (93%) revealed high sensitivities, especially for amphetamine screening. Poor specificities (<90%) and accuracies (<95%) were observed for all tests except for low-prevalent substances (e.g., opiates). For drug testing in OF, Δ9 -tetrahydrocannabinol (THC) still seems to be a compound of concern due to poor sensitivity (RapidSTAT®, 77%; DrugWipe® 6S, 85%), although the results indicate improvements compared with previously reported data. Although the obtained data indicate reliable detection for some substances, deployment of trained police officers is inevitable to identify DUID suspects by signs of recent use and recognising impairment. SN - 1942-7611 UR - https://www.unboundmedicine.com/medline/citation/35343088/Evaluation_of_RapidSTAT®_DrugWipe®_6S_DrugScreen®_5TK_and_DrugScreen®_7TR_for_on_site_drug_testing_in_German_police_roadside_traffic_patrol_ DB - PRIME DP - Unbound Medicine ER -