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Skin, hair and beyond: the impact of menopause.
Climacteric. 2022 Apr 04 [Online ahead of print]C

Abstract

The skin is an endocrine organ and a major target of hormones such as estrogens, androgens and cortisol. Besides vasomotor symptoms (VMS), skin and hair symptoms often receive less attention than other menopausal symptoms despite having a significant negative effect on quality of life. Skin and mucosal menopausal symptoms include dryness and pruritus, thinning and atrophy, wrinkles and sagging, poor wound healing and reduced vascularity, whereas skin premalignant and malignant lesions and skin aging signs are almost exclusively caused by environmental factors, especially solar radiation. Hair menopausal symptoms include reduced hair growth and density on the scalp (diffuse effluvium due to follicular rarefication and/or androgenetic alopecia of female pattern), altered hair quality and structure, and increased unwanted hair growth on facial areas. Hormone replacement therapy (HRT) is not indicated for skin and hair symptoms alone due to the risk-benefit balance, but wider potential benefits of HRT (beyond estrogen's effect on VMS, bone, breast, heart and blood vessels) to include skin, hair and mucosal benefits should be discussed with women so that they will be able to make the best possible informed decisions on how to prevent or manage their menopausal symptoms.

Authors+Show Affiliations

Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences, Brandenburg, Germany.Department of Dermatology, Venerology and Allergology, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany.Dermoiatriki Athens, Athens, Greece.Clider Clínica Dermatológica Roó, Universidad Francisco de Vitoria, Madrid, Spain.Gynecology, Saint-Louis Hospital, Paris, France.Laboratoires Vichy, Levallois-Perret, France.School of Medicine, New York University Grossman, New York, NY, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35377827

Citation

Zouboulis, C C., et al. "Skin, Hair and Beyond: the Impact of Menopause." Climacteric : the Journal of the International Menopause Society, 2022, pp. 1-9.
Zouboulis CC, Blume-Peytavi U, Kosmadaki M, et al. Skin, hair and beyond: the impact of menopause. Climacteric. 2022.
Zouboulis, C. C., Blume-Peytavi, U., Kosmadaki, M., Roó, E., Vexiau-Robert, D., Kerob, D., & Goldstein, S. R. (2022). Skin, hair and beyond: the impact of menopause. Climacteric : the Journal of the International Menopause Society, 1-9. https://doi.org/10.1080/13697137.2022.2050206
Zouboulis CC, et al. Skin, Hair and Beyond: the Impact of Menopause. Climacteric. 2022 Apr 4;1-9. PubMed PMID: 35377827.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Skin, hair and beyond: the impact of menopause. AU - Zouboulis,C C, AU - Blume-Peytavi,U, AU - Kosmadaki,M, AU - Roó,E, AU - Vexiau-Robert,D, AU - Kerob,D, AU - Goldstein,S R, Y1 - 2022/04/04/ PY - 2022/4/4/entrez PY - 2022/4/5/pubmed PY - 2022/4/5/medline KW - Menopause KW - exposome KW - hair KW - hormone replacement therapy KW - hormones KW - mucosa KW - perimenopause KW - skin SP - 1 EP - 9 JF - Climacteric : the journal of the International Menopause Society JO - Climacteric N2 - The skin is an endocrine organ and a major target of hormones such as estrogens, androgens and cortisol. Besides vasomotor symptoms (VMS), skin and hair symptoms often receive less attention than other menopausal symptoms despite having a significant negative effect on quality of life. Skin and mucosal menopausal symptoms include dryness and pruritus, thinning and atrophy, wrinkles and sagging, poor wound healing and reduced vascularity, whereas skin premalignant and malignant lesions and skin aging signs are almost exclusively caused by environmental factors, especially solar radiation. Hair menopausal symptoms include reduced hair growth and density on the scalp (diffuse effluvium due to follicular rarefication and/or androgenetic alopecia of female pattern), altered hair quality and structure, and increased unwanted hair growth on facial areas. Hormone replacement therapy (HRT) is not indicated for skin and hair symptoms alone due to the risk-benefit balance, but wider potential benefits of HRT (beyond estrogen's effect on VMS, bone, breast, heart and blood vessels) to include skin, hair and mucosal benefits should be discussed with women so that they will be able to make the best possible informed decisions on how to prevent or manage their menopausal symptoms. SN - 1473-0804 UR - https://www.unboundmedicine.com/medline/citation/35377827/Skin,_hair_and_beyond:_the_impact_of_menopause. L2 - https://www.tandfonline.com/doi/full/10.1080/13697137.2022.2050206 DB - PRIME DP - Unbound Medicine ER -
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