Tags

Type your tag names separated by a space and hit enter

Endocrine cell proliferation and carcinoid development: a review of new aspects of hypergastrinaemic atrophic gastritis.
Digestion 1986; 35 Suppl 1:106-15D

Abstract

The accumulating evidence of an association between antrum-sparing hypergastrinaemic atrophic gastritis, frequently associated with pernicious anaemia, and the occurrence of gastric carcinoid tumours is briefly reviewed. The development of argyrophil cell carcinoid tumours in the atrophic fundic mucosa seems to be related to argyrophil cell hyperplasia caused by hypergastrinaemia. Epidemiologic considerations indicate that the gastric carcinoid generally is underdiagnosed and that the incidence of this tumour is higher than previously recognized. The clinical relevance of minute gastric carcinoids, or endocrine cell 'adenomas', is obscure. However, larger tumours should be regarded as potentially malignant. These findings are relevant to the aspect of long-term medically induced achlorhydria leading to hypergastrinaemia.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

3539677

Citation

Borch, K, et al. "Endocrine Cell Proliferation and Carcinoid Development: a Review of New Aspects of Hypergastrinaemic Atrophic Gastritis." Digestion, vol. 35 Suppl 1, 1986, pp. 106-15.
Borch K, Renvall H, Liedberg G. Endocrine cell proliferation and carcinoid development: a review of new aspects of hypergastrinaemic atrophic gastritis. Digestion. 1986;35 Suppl 1:106-15.
Borch, K., Renvall, H., & Liedberg, G. (1986). Endocrine cell proliferation and carcinoid development: a review of new aspects of hypergastrinaemic atrophic gastritis. Digestion, 35 Suppl 1, pp. 106-15.
Borch K, Renvall H, Liedberg G. Endocrine Cell Proliferation and Carcinoid Development: a Review of New Aspects of Hypergastrinaemic Atrophic Gastritis. Digestion. 1986;35 Suppl 1:106-15. PubMed PMID: 3539677.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endocrine cell proliferation and carcinoid development: a review of new aspects of hypergastrinaemic atrophic gastritis. AU - Borch,K, AU - Renvall,H, AU - Liedberg,G, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 106 EP - 15 JF - Digestion JO - Digestion VL - 35 Suppl 1 N2 - The accumulating evidence of an association between antrum-sparing hypergastrinaemic atrophic gastritis, frequently associated with pernicious anaemia, and the occurrence of gastric carcinoid tumours is briefly reviewed. The development of argyrophil cell carcinoid tumours in the atrophic fundic mucosa seems to be related to argyrophil cell hyperplasia caused by hypergastrinaemia. Epidemiologic considerations indicate that the gastric carcinoid generally is underdiagnosed and that the incidence of this tumour is higher than previously recognized. The clinical relevance of minute gastric carcinoids, or endocrine cell 'adenomas', is obscure. However, larger tumours should be regarded as potentially malignant. These findings are relevant to the aspect of long-term medically induced achlorhydria leading to hypergastrinaemia. SN - 0012-2823 UR - https://www.unboundmedicine.com/medline/citation/3539677/Endocrine_cell_proliferation_and_carcinoid_development:_a_review_of_new_aspects_of_hypergastrinaemic_atrophic_gastritis_ L2 - https://www.karger.com?DOI=10.1159/000199386 DB - PRIME DP - Unbound Medicine ER -