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Management and Cure of Gouty Arthritis.
Rheum Dis Clin North Am. 2022 05; 48(2):479-492.RD

Abstract

Gout is the most common inflammatory arthritis in the United States. Gouty arthritis is associated with significant morbidity and mortality and is the result of chronic hyperuricemia. Gout is effectively managed and potentially cured by decreasing the overall urate burden with serum urate-lowering therapy. When serum urate is maintained at less than 6.0 mg/dL, urate deposition is resolved, and gout can be cured. Unfortunately, because of less than optimal physician monitoring and dose escalation, many patients do not achieve these urate levels.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Keller SF
Department of Rheumatic & Immunologic Diseases, The Cleveland Clinic, 9500 Euclid Avenue A50, Cleveland, OH 44915, USA. Electronic address: kellers@ccf.org.
Mandell BF
Department of Rheumatic & Immunologic Diseases, The Cleveland Clinic, 9500 Euclid Avenue A50, Cleveland, OH 44915, USA.

MeSH

Arthritis, GoutyGoutGout SuppressantsHumansHyperuricemiaUric Acid

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

35400373

Citation

Keller, Sarah F., and Brian F. Mandell. "Management and Cure of Gouty Arthritis." Rheumatic Diseases Clinics of North America, vol. 48, no. 2, 2022, pp. 479-492.
Keller SF, Mandell BF. Management and Cure of Gouty Arthritis. Rheum Dis Clin North Am. 2022;48(2):479-492.
Keller, S. F., & Mandell, B. F. (2022). Management and Cure of Gouty Arthritis. Rheumatic Diseases Clinics of North America, 48(2), 479-492. https://doi.org/10.1016/j.rdc.2022.03.001
Keller SF, Mandell BF. Management and Cure of Gouty Arthritis. Rheum Dis Clin North Am. 2022;48(2):479-492. PubMed PMID: 35400373.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Management and Cure of Gouty Arthritis. AU - Keller,Sarah F, AU - Mandell,Brian F, PY - 2022/4/11/entrez PY - 2022/4/12/pubmed PY - 2022/4/13/medline KW - Gout KW - Hyperuricemia KW - Inflammatory arthritis KW - Treat-to-target KW - Uric acid SP - 479 EP - 492 JF - Rheumatic diseases clinics of North America JO - Rheum Dis Clin North Am VL - 48 IS - 2 N2 - Gout is the most common inflammatory arthritis in the United States. Gouty arthritis is associated with significant morbidity and mortality and is the result of chronic hyperuricemia. Gout is effectively managed and potentially cured by decreasing the overall urate burden with serum urate-lowering therapy. When serum urate is maintained at less than 6.0 mg/dL, urate deposition is resolved, and gout can be cured. Unfortunately, because of less than optimal physician monitoring and dose escalation, many patients do not achieve these urate levels. SN - 1558-3163 UR - https://www.unboundmedicine.com/medline/citation/35400373/Management_and_Cure_of_Gouty_Arthritis_ DB - PRIME DP - Unbound Medicine ER -