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Body burden and influencing factors of polychlorinated dibenzodioxins and dibenzofurans (PCDD/Fs) in male workers from a municipal waste incineration plant in China.
Environ Pollut. 2022 Jul 15; 305:119272.EP

Abstract

Emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) from municipal solid waste incinerators (MSWIs) have aroused public concern around the world. However, biomonitoring evidence regarding the influence of MSWIs on the human body burden of PCDD/Fs is scarce. The aim of this study is to investigate the human body burden levels of PCDD/Fs in MSWI workers and to further explore the potential influencing factors, including duration of occupation and dietary habits, on the PCDD/F levels. A total of 98 paired serum samples from MSWI workers and non-MSWI workers were collected. Seventeen 2,3,7,8-chlorine substituted PCDD/Fs in the serums were analyzed using an isotope dilution high-resolution gas chromatograph/high-resolution mass spectrometer (HRGC/HRMS). The results showed that the mean levels of toxic equivalent (TEQ)-PCDD/Fs for the MSWI workers and the control group were 18.28 pg TEQ g-1 lipid and 5.81 pg TEQ g-1 lipid, respectively. Significantly higher concentrations of PCDD/Fs existed in the incinerator workers compared with the control subjects after adjustment of the confounding factors. OCDD was the most abundant congener in both the MSWI workers and the control subjects, accounting for 82.2% and 89.4% of the ∑17PCDD/Fs, respectively. The serum levels of PCDFs in the MSWI workers increased with the duration of occupation (β = 0.498, P = 0.031), and a higher total concentration of PCDD/Fs were present in senior workers classified as production supervisors than routine operation staff (β = 8.809, P = 0.008). No significant relationship was found between the PCDD/F concentrations and dietary habits. This study was the first to explore the associations between the body burden of PCDD/Fs and occupational exposure as well as dietary intake of MSWI workers in China. The findings provide scientific information for health risk assessments of human exposure to PCDD/Fs.

Authors+Show Affiliations

Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China; Shenzhen Maternity & Child Healthcare Hospital, Shenzhen, 518017, PR China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China. Electronic address: 969676617@qq.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35413407

Citation

Peng, Jinling, et al. "Body Burden and Influencing Factors of Polychlorinated Dibenzodioxins and Dibenzofurans (PCDD/Fs) in Male Workers From a Municipal Waste Incineration Plant in China." Environmental Pollution (Barking, Essex : 1987), vol. 305, 2022, p. 119272.
Peng J, Jiang Y, Ai C, et al. Body burden and influencing factors of polychlorinated dibenzodioxins and dibenzofurans (PCDD/Fs) in male workers from a municipal waste incineration plant in China. Environ Pollut. 2022;305:119272.
Peng, J., Jiang, Y., Ai, C., Liu, Y., Lin, X., Zhou, J., & Zhang, J. (2022). Body burden and influencing factors of polychlorinated dibenzodioxins and dibenzofurans (PCDD/Fs) in male workers from a municipal waste incineration plant in China. Environmental Pollution (Barking, Essex : 1987), 305, 119272. https://doi.org/10.1016/j.envpol.2022.119272
Peng J, et al. Body Burden and Influencing Factors of Polychlorinated Dibenzodioxins and Dibenzofurans (PCDD/Fs) in Male Workers From a Municipal Waste Incineration Plant in China. Environ Pollut. 2022 Jul 15;305:119272. PubMed PMID: 35413407.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Body burden and influencing factors of polychlorinated dibenzodioxins and dibenzofurans (PCDD/Fs) in male workers from a municipal waste incineration plant in China. AU - Peng,Jinling, AU - Jiang,Yousheng, AU - Ai,Chunyan, AU - Liu,Yuan, AU - Lin,Xiaoshi, AU - Zhou,Jian, AU - Zhang,Jianqing, Y1 - 2022/04/09/ PY - 2021/12/30/received PY - 2022/03/30/revised PY - 2022/04/04/accepted PY - 2022/4/13/pubmed PY - 2022/4/13/medline PY - 2022/4/12/entrez KW - Body burden KW - Incinerator workers KW - Influencing factors KW - PCDD/Fs SP - 119272 EP - 119272 JF - Environmental pollution (Barking, Essex : 1987) JO - Environ Pollut VL - 305 N2 - Emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) from municipal solid waste incinerators (MSWIs) have aroused public concern around the world. However, biomonitoring evidence regarding the influence of MSWIs on the human body burden of PCDD/Fs is scarce. The aim of this study is to investigate the human body burden levels of PCDD/Fs in MSWI workers and to further explore the potential influencing factors, including duration of occupation and dietary habits, on the PCDD/F levels. A total of 98 paired serum samples from MSWI workers and non-MSWI workers were collected. Seventeen 2,3,7,8-chlorine substituted PCDD/Fs in the serums were analyzed using an isotope dilution high-resolution gas chromatograph/high-resolution mass spectrometer (HRGC/HRMS). The results showed that the mean levels of toxic equivalent (TEQ)-PCDD/Fs for the MSWI workers and the control group were 18.28 pg TEQ g-1 lipid and 5.81 pg TEQ g-1 lipid, respectively. Significantly higher concentrations of PCDD/Fs existed in the incinerator workers compared with the control subjects after adjustment of the confounding factors. OCDD was the most abundant congener in both the MSWI workers and the control subjects, accounting for 82.2% and 89.4% of the ∑17PCDD/Fs, respectively. The serum levels of PCDFs in the MSWI workers increased with the duration of occupation (β = 0.498, P = 0.031), and a higher total concentration of PCDD/Fs were present in senior workers classified as production supervisors than routine operation staff (β = 8.809, P = 0.008). No significant relationship was found between the PCDD/F concentrations and dietary habits. This study was the first to explore the associations between the body burden of PCDD/Fs and occupational exposure as well as dietary intake of MSWI workers in China. The findings provide scientific information for health risk assessments of human exposure to PCDD/Fs. SN - 1873-6424 UR - https://www.unboundmedicine.com/medline/citation/35413407/Body_burden_and_influencing_factors_of_polychlorinated_dibenzodioxins_and_dibenzofurans__PCDD/Fs__in_male_workers_from_a_municipal_waste_incineration_plant_in_China_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0269-7491(22)00486-9 DB - PRIME DP - Unbound Medicine ER -