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Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
Int J Environ Res Public Health. 2022 04 11; 19(8)IJ

Abstract

Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron variants were estimated to lead to more severity and deaths than other variants. Furthermore, these variants have some contagious characteristics involving high transmissibility, more severe illness, and an increased mortality rate. All outbreaks caused by the Delta variant have been rapidly skyrocketing in infection cases in communities despite tough restrictions in 2021. Apart from it, the United States, the United Kingdom and other high-rate vaccination rollout countries are still wrestling with this trend because the Delta variant can result in a significant number of breakthrough infections. However, the pandemic has changed since the latest SARS-CoV-2 variant in late 2021 in South Africa, Omicron. The preliminary data suggest that the Omicron variant possesses 100-fold greater than the Delta variant in transmissibility. Therefore, this paper aims to review these characteristics based on the available meta-data and information from the first emergence to recent days. Australia and the five most affected countries, including the United States, India, Brazil, France, as well as the United Kingdom, are selected in order to review the transmissibility, severity and fatality due to Delta and Omicron variants. Finally, the vaccination programs for each country are also reviewed as the main factor in prevention.

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Authors+Show Affiliations

School of Mechanical and Mechatronic Engineering, University of Technology Sydney, Ultimo, NSW 2007, Australia.

Larpruenrudee P

School of Mechanical and Mechatronic Engineering, University of Technology Sydney, Ultimo, NSW 2007, Australia.

School of Mechanical and Mechatronic Engineering, University of Technology Sydney, Ultimo, NSW 2007, Australia.

School of Life Sciences, University of Technology Sydney, Ultimo, NSW 2007, Australia.

School of Mechanical and Mechatronic Engineering, University of Technology Sydney, Ultimo, NSW 2007, Australia.

School of Mechanical, Medical and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD 4000, Australia.

School of Mechanical and Mechatronic Engineering, University of Technology Sydney, Ultimo, NSW 2007, Australia.

MeSH

COVID-19Disease OutbreaksHumansPandemicsSARS-CoV-2United States

Pub Type(s)

Journal Article

Review

Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

35457468

Citation

Duong, Bao V., et al. "Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?" International Journal of Environmental Research and Public Health, vol. 19, no. 8, 2022.

Duong BV, Larpruenrudee P, Fang T, et al. Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant? Int J Environ Res Public Health. 2022;19(8).

Duong, B. V., Larpruenrudee, P., Fang, T., Hossain, S. I., Saha, S. C., Gu, Y., & Islam, M. S. (2022). Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant? International Journal of Environmental Research and Public Health, 19(8). https://doi.org/10.3390/ijerph19084586

Duong BV, et al. Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant. Int J Environ Res Public Health. 2022 04 11;19(8) PubMed PMID: 35457468.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant? AU - Duong,Bao V, AU - Larpruenrudee,Puchanee, AU - Fang,Tianxin, AU - Hossain,Sheikh I, AU - Saha,Suvash C, AU - Gu,Yuantong, AU - Islam,Mohammad S, Y1 - 2022/04/11/ PY - 2022/03/02/received PY - 2022/04/06/revised PY - 2022/04/07/accepted PY - 2022/4/23/entrez PY - 2022/4/24/pubmed PY - 2022/4/27/medline KW - COVID-19 KW - Delta variant KW - Omicron variant KW - SARS-CoV-2 KW - severity and mortality KW - transmissibility KW - variants of concern JF - International journal of environmental research and public health JO - Int J Environ Res Public Health VL - 19 IS - 8 N2 - Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron variants were estimated to lead to more severity and deaths than other variants. Furthermore, these variants have some contagious characteristics involving high transmissibility, more severe illness, and an increased mortality rate. All outbreaks caused by the Delta variant have been rapidly skyrocketing in infection cases in communities despite tough restrictions in 2021. Apart from it, the United States, the United Kingdom and other high-rate vaccination rollout countries are still wrestling with this trend because the Delta variant can result in a significant number of breakthrough infections. However, the pandemic has changed since the latest SARS-CoV-2 variant in late 2021 in South Africa, Omicron. The preliminary data suggest that the Omicron variant possesses 100-fold greater than the Delta variant in transmissibility. Therefore, this paper aims to review these characteristics based on the available meta-data and information from the first emergence to recent days. Australia and the five most affected countries, including the United States, India, Brazil, France, as well as the United Kingdom, are selected in order to review the transmissibility, severity and fatality due to Delta and Omicron variants. Finally, the vaccination programs for each country are also reviewed as the main factor in prevention. SN - 1660-4601 UR - https://www.unboundmedicine.com/medline/citation/35457468/Is_the_SARS_CoV_2_Omicron_Variant_Deadlier_and_More_Transmissible_Than_Delta_Variant DB - PRIME DP - Unbound Medicine ER -