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Usefulness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison syndrome.
Ann Surg. 1987 Mar; 205(3):230-9.AnnS

Abstract

Secretin was injected into a feeding or nonfeeding artery of a gastrinoma and blood samples were taken from the hepatic vein (HV) or a peripheral artery (PA) to measure the changes of serum immunoreactive gastrin concentration (IRG). The IRG in the HV rose within 40 seconds and in the PA rose within 60 seconds after the injection of secretin into a feeding artery, but not after secretin was injected into a nonfeeder. These results indicated that secretin directly stimulates a gastrinoma to release gastrin in vivo. The selective arterial secretin injection test (SASI test) was applied in three patients in whom gastrinomas could not be located by computed tomography, ultrasonography, or arteriography, and functioning gastrinomas were located in all three patients. In one patient, malignant gastrinomas in the head of the pancreas and in the duodenum could be resected radically with the help of this test.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3548610

Citation

Imamura, M, et al. "Usefulness of Selective Arterial Secretin Injection Test for Localization of Gastrinoma in the Zollinger-Ellison Syndrome." Annals of Surgery, vol. 205, no. 3, 1987, pp. 230-9.
Imamura M, Takahashi K, Adachi H, et al. Usefulness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison syndrome. Ann Surg. 1987;205(3):230-9.
Imamura, M., Takahashi, K., Adachi, H., Minematsu, S., Shimada, Y., Naito, M., Suzuki, T., Tobe, T., & Azuma, T. (1987). Usefulness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison syndrome. Annals of Surgery, 205(3), 230-9.
Imamura M, et al. Usefulness of Selective Arterial Secretin Injection Test for Localization of Gastrinoma in the Zollinger-Ellison Syndrome. Ann Surg. 1987;205(3):230-9. PubMed PMID: 3548610.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Usefulness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison syndrome. AU - Imamura,M, AU - Takahashi,K, AU - Adachi,H, AU - Minematsu,S, AU - Shimada,Y, AU - Naito,M, AU - Suzuki,T, AU - Tobe,T, AU - Azuma,T, PY - 1987/3/1/pubmed PY - 1987/3/1/medline PY - 1987/3/1/entrez SP - 230 EP - 9 JF - Annals of surgery JO - Ann Surg VL - 205 IS - 3 N2 - Secretin was injected into a feeding or nonfeeding artery of a gastrinoma and blood samples were taken from the hepatic vein (HV) or a peripheral artery (PA) to measure the changes of serum immunoreactive gastrin concentration (IRG). The IRG in the HV rose within 40 seconds and in the PA rose within 60 seconds after the injection of secretin into a feeding artery, but not after secretin was injected into a nonfeeder. These results indicated that secretin directly stimulates a gastrinoma to release gastrin in vivo. The selective arterial secretin injection test (SASI test) was applied in three patients in whom gastrinomas could not be located by computed tomography, ultrasonography, or arteriography, and functioning gastrinomas were located in all three patients. In one patient, malignant gastrinomas in the head of the pancreas and in the duodenum could be resected radically with the help of this test. SN - 0003-4932 UR - https://www.unboundmedicine.com/medline/citation/3548610/Usefulness_of_selective_arterial_secretin_injection_test_for_localization_of_gastrinoma_in_the_Zollinger_Ellison_syndrome_ L2 - https://Insights.ovid.com/pubmed?pmid=3548610 DB - PRIME DP - Unbound Medicine ER -