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Endolymph formation in the inner ear of pigeons.

Abstract

The endolymphatic space of pigeons was studied by using double-barrelled electrodes with a potassium liquid ion exchanger. The K+ activity of the endolymph was 155 mM in the cochlea and 133 mM in the ampulla, respectively. Positive DC potential in the cochlea (+14.5 mV) was much lower than in guinea pigs (+80 mV) whereas in the ampulla of pigeons the DC potential (+7.4 mV) was 2 times higher than that of guinea pigs (+3.9 mV). General application of ethacrynic acid in pigeons induced a weak change in DC potential and no typical intercellular edema in the cochlea and ampulla. Local application of ethacrynic acid and ouabain in the cochlea and ampulla of pigeons induced a negative DC potential of between -30 and -40 mV. This negative DC potential was higher than the anoxia-induced negative potential. Short hypoxia during a drug-induced DC potential resulted in a decrease in DC potential above the diffusion potential. Below the diffusion potential additional hypoxia increased the DC potential independent of the cause of intoxication.

Authors

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Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

3561967

Citation

Ninoyu, O, et al. "Endolymph Formation in the Inner Ear of Pigeons." ORL; Journal for Oto-rhino-laryngology and Its Related Specialties, vol. 49, no. 1, 1987, pp. 1-8.
Ninoyu O, Hommerich C, Morgenstern C. Endolymph formation in the inner ear of pigeons. ORL J Otorhinolaryngol Relat Spec. 1987;49(1):1-8.
Ninoyu, O., Hommerich, C., & Morgenstern, C. (1987). Endolymph formation in the inner ear of pigeons. ORL; Journal for Oto-rhino-laryngology and Its Related Specialties, 49(1), pp. 1-8.
Ninoyu O, Hommerich C, Morgenstern C. Endolymph Formation in the Inner Ear of Pigeons. ORL J Otorhinolaryngol Relat Spec. 1987;49(1):1-8. PubMed PMID: 3561967.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endolymph formation in the inner ear of pigeons. AU - Ninoyu,O, AU - Hommerich,C, AU - Morgenstern,C, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 1 EP - 8 JF - ORL; journal for oto-rhino-laryngology and its related specialties JO - ORL J. Otorhinolaryngol. Relat. Spec. VL - 49 IS - 1 N2 - The endolymphatic space of pigeons was studied by using double-barrelled electrodes with a potassium liquid ion exchanger. The K+ activity of the endolymph was 155 mM in the cochlea and 133 mM in the ampulla, respectively. Positive DC potential in the cochlea (+14.5 mV) was much lower than in guinea pigs (+80 mV) whereas in the ampulla of pigeons the DC potential (+7.4 mV) was 2 times higher than that of guinea pigs (+3.9 mV). General application of ethacrynic acid in pigeons induced a weak change in DC potential and no typical intercellular edema in the cochlea and ampulla. Local application of ethacrynic acid and ouabain in the cochlea and ampulla of pigeons induced a negative DC potential of between -30 and -40 mV. This negative DC potential was higher than the anoxia-induced negative potential. Short hypoxia during a drug-induced DC potential resulted in a decrease in DC potential above the diffusion potential. Below the diffusion potential additional hypoxia increased the DC potential independent of the cause of intoxication. SN - 0301-1569 UR - https://www.unboundmedicine.com/medline/citation/3561967/Endolymph_formation_in_the_inner_ear_of_pigeons_ L2 - https://www.karger.com?DOI=10.1159/000275899 DB - PRIME DP - Unbound Medicine ER -