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Is there any association between adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity with Bacterial Vaginosis? Results from a Case-Control study.
BMC Womens Health. 2022 Jun 20; 22(1):244.BW

Abstract

BACKGROUND

Bacterial vaginosis, BV, is a common inflammatory vaginal dysbiosis. The Mediterranean diet, MD, containing foods rich in antioxidant compounds, is shown to be beneficial for inflammatory conditions. This study aimed to investigate the association between MD adherence and dietary total antioxidant capacity (DTAC) with BV.

METHODS

This case-control study was conducted on 143 BV-affected and 151 healthy individuals aged between 15 and 45 years. The Amsel criteria were used to detect newly diagnosed patients with BV by a gynecologist. The 168-item food frequency questionnaire (FFQ) was used to record participants' dietary intakes in the last year. The reported data in the FFQ was used to measure adherence to the MD by calculating the Medi-Lite score and to measure the DTAC by calculating ferric-reducing antioxidant power, FRAP, based on the related databases. Logistic regression models were used to determine the association between Medi-Lite and DTAC and BV odds.

RESULTS

The highest tertile of Medi-Lite score was associated with a reduced odds of BV in the crude model (Odds Ratio, OR: 0.49, 95% Confidence Interval, 95% CI 0.25, 0.96, P for trend: 0.023). This significant inverse association was not observed in the last model adjusted for age, body mass index (kg/m2), waist circumferences (cm), cigarette smoking, frequency of pregnancy, and physical activity (MET/h/d). In crude and adjusted odels, BV odds decreased in the highest tertile of vegetable (adjusted OR, aOR: 0.32, 95% CI 0.16, 0.63, P for trend: 0.001), fish (aOR: 0.46, 95% CI 0.25, 0.84, P for trend: 0.009), legumes (aOR: 0.26, 95% CI 0.14, 0.50, P for trend < 0.001), and meat (aOR: 0.29, 95% CI 0.15, 0.56, P for trend < 0.001) groups. There was no significant association between DTAC and BV odds.

CONCLUSIONS

The significant inverse association between the MD adherence and BV odds did not remain after modifying for confounders; besides, DTAC was not associated with BV odds. However, some of the MD components might be associated with a reduced odds of BV.

Authors+Show Affiliations

Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. Student Research Committee, Faculty of Public Health Branch, Iran University of Medical Sciences, Tehran, Iran.Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, No 7, Hafezi St., Farahzadi Blvd., P.O. Box 19395-4741, Tehran, 1981619573, Iran. gh.eslamian@sbmu.ac.ir.Department of Obstetrics and Gynecology, School of Medicine, Preventative Gynecology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

35725424

Citation

Noormohammadi, Morvarid, et al. "Is There Any Association Between Adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity With Bacterial Vaginosis? Results From a Case-Control Study." BMC Women's Health, vol. 22, no. 1, 2022, p. 244.
Noormohammadi M, Eslamian G, Kazemi SN, et al. Is there any association between adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity with Bacterial Vaginosis? Results from a Case-Control study. BMC Womens Health. 2022;22(1):244.
Noormohammadi, M., Eslamian, G., Kazemi, S. N., & Rashidkhani, B. (2022). Is there any association between adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity with Bacterial Vaginosis? Results from a Case-Control study. BMC Women's Health, 22(1), 244. https://doi.org/10.1186/s12905-022-01833-8
Noormohammadi M, et al. Is There Any Association Between Adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity With Bacterial Vaginosis? Results From a Case-Control Study. BMC Womens Health. 2022 Jun 20;22(1):244. PubMed PMID: 35725424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Is there any association between adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity with Bacterial Vaginosis? Results from a Case-Control study. AU - Noormohammadi,Morvarid, AU - Eslamian,Ghazaleh, AU - Kazemi,Seyyedeh Neda, AU - Rashidkhani,Bahram, Y1 - 2022/06/20/ PY - 2022/3/3/received PY - 2022/6/16/accepted PY - 2022/6/20/entrez PY - 2022/6/21/pubmed PY - 2022/6/23/medline KW - Bacterial vaginosis KW - Case–control study KW - Inflammation KW - Mediterranean diet KW - Oxidative stress SP - 244 EP - 244 JF - BMC women's health JO - BMC Womens Health VL - 22 IS - 1 N2 - BACKGROUND: Bacterial vaginosis, BV, is a common inflammatory vaginal dysbiosis. The Mediterranean diet, MD, containing foods rich in antioxidant compounds, is shown to be beneficial for inflammatory conditions. This study aimed to investigate the association between MD adherence and dietary total antioxidant capacity (DTAC) with BV. METHODS: This case-control study was conducted on 143 BV-affected and 151 healthy individuals aged between 15 and 45 years. The Amsel criteria were used to detect newly diagnosed patients with BV by a gynecologist. The 168-item food frequency questionnaire (FFQ) was used to record participants' dietary intakes in the last year. The reported data in the FFQ was used to measure adherence to the MD by calculating the Medi-Lite score and to measure the DTAC by calculating ferric-reducing antioxidant power, FRAP, based on the related databases. Logistic regression models were used to determine the association between Medi-Lite and DTAC and BV odds. RESULTS: The highest tertile of Medi-Lite score was associated with a reduced odds of BV in the crude model (Odds Ratio, OR: 0.49, 95% Confidence Interval, 95% CI 0.25, 0.96, P for trend: 0.023). This significant inverse association was not observed in the last model adjusted for age, body mass index (kg/m2), waist circumferences (cm), cigarette smoking, frequency of pregnancy, and physical activity (MET/h/d). In crude and adjusted odels, BV odds decreased in the highest tertile of vegetable (adjusted OR, aOR: 0.32, 95% CI 0.16, 0.63, P for trend: 0.001), fish (aOR: 0.46, 95% CI 0.25, 0.84, P for trend: 0.009), legumes (aOR: 0.26, 95% CI 0.14, 0.50, P for trend < 0.001), and meat (aOR: 0.29, 95% CI 0.15, 0.56, P for trend < 0.001) groups. There was no significant association between DTAC and BV odds. CONCLUSIONS: The significant inverse association between the MD adherence and BV odds did not remain after modifying for confounders; besides, DTAC was not associated with BV odds. However, some of the MD components might be associated with a reduced odds of BV. SN - 1472-6874 UR - https://www.unboundmedicine.com/medline/citation/35725424/Is_there_any_association_between_adherence_to_the_Mediterranean_Diet_and_Dietary_Total_Antioxidant_Capacity_with_Bacterial_Vaginosis_Results_from_a_Case-Control_study. DB - PRIME DP - Unbound Medicine ER -