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A review on phytochemicals, metabolic profiles and pharmacokinetics studies of the different parts (juice, seeds, peel, flowers, leaves and bark) of pomegranate (Punica granatum L.).
Food Chem. 2022 Nov 30; 395:133600.FC

Abstract

Pomegranate is a fruit-bearing tree. Pomegranate flowers, leaves, bark, fruit juice, peel and seeds were reported to have pharmacological effects. Recently, the researches about phytochemicals, metabolism and pharmacokinetics studies of different parts of pomegranate were carried out. There is a lack of summary on different parts of pomegranate. Furthermore, we were interested in potential correlations and differences on the phytochemicals, metabolism and pharmacokinetics studies between the different parts of pomegranate. This review is aimed to provide a comprehensive overview of reported researches on different parts of pomegranate about phytochemicals, metabolism and pharmacokinetics studies. Besides, we introduced analysis strategies for identifying phytochemicals in foods/plants and metabolites in biosamples using LC-HR MSn techniques. Furthermore, we firstly speculated structures and the maximum number of constitutional isomers of ellagitannins and gallotannins. This review is helpful for further application to discover more active compounds and their metabolites from pomegranate and other plants/foods.

Authors+Show Affiliations

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China. Electronic address: chaozhi@smu.edu.cn.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

35793588

Citation

Yisimayili, Zainaipuguli, and Zhi Chao. "A Review On Phytochemicals, Metabolic Profiles and Pharmacokinetics Studies of the Different Parts (juice, Seeds, Peel, Flowers, Leaves and Bark) of Pomegranate (Punica Granatum L.)." Food Chemistry, vol. 395, 2022, p. 133600.
Yisimayili Z, Chao Z. A review on phytochemicals, metabolic profiles and pharmacokinetics studies of the different parts (juice, seeds, peel, flowers, leaves and bark) of pomegranate (Punica granatum L.). Food Chem. 2022;395:133600.
Yisimayili, Z., & Chao, Z. (2022). A review on phytochemicals, metabolic profiles and pharmacokinetics studies of the different parts (juice, seeds, peel, flowers, leaves and bark) of pomegranate (Punica granatum L.). Food Chemistry, 395, 133600. https://doi.org/10.1016/j.foodchem.2022.133600
Yisimayili Z, Chao Z. A Review On Phytochemicals, Metabolic Profiles and Pharmacokinetics Studies of the Different Parts (juice, Seeds, Peel, Flowers, Leaves and Bark) of Pomegranate (Punica Granatum L.). Food Chem. 2022 Nov 30;395:133600. PubMed PMID: 35793588.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A review on phytochemicals, metabolic profiles and pharmacokinetics studies of the different parts (juice, seeds, peel, flowers, leaves and bark) of pomegranate (Punica granatum L.). AU - Yisimayili,Zainaipuguli, AU - Chao,Zhi, Y1 - 2022/06/30/ PY - 2022/02/08/received PY - 2022/06/13/revised PY - 2022/06/27/accepted PY - 2022/7/7/pubmed PY - 2022/8/4/medline PY - 2022/7/6/entrez KW - Chemical compounds KW - Ellagitannins KW - Gallotannins KW - LC–MS/MS KW - Metabolism KW - Punica granatum L. SP - 133600 EP - 133600 JF - Food chemistry JO - Food Chem VL - 395 N2 - Pomegranate is a fruit-bearing tree. Pomegranate flowers, leaves, bark, fruit juice, peel and seeds were reported to have pharmacological effects. Recently, the researches about phytochemicals, metabolism and pharmacokinetics studies of different parts of pomegranate were carried out. There is a lack of summary on different parts of pomegranate. Furthermore, we were interested in potential correlations and differences on the phytochemicals, metabolism and pharmacokinetics studies between the different parts of pomegranate. This review is aimed to provide a comprehensive overview of reported researches on different parts of pomegranate about phytochemicals, metabolism and pharmacokinetics studies. Besides, we introduced analysis strategies for identifying phytochemicals in foods/plants and metabolites in biosamples using LC-HR MSn techniques. Furthermore, we firstly speculated structures and the maximum number of constitutional isomers of ellagitannins and gallotannins. This review is helpful for further application to discover more active compounds and their metabolites from pomegranate and other plants/foods. SN - 1873-7072 UR - https://www.unboundmedicine.com/medline/citation/35793588/A_review_on_phytochemicals_metabolic_profiles_and_pharmacokinetics_studies_of_the_different_parts__juice_seeds_peel_flowers_leaves_and_bark__of_pomegranate__Punica_granatum_L___ DB - PRIME DP - Unbound Medicine ER -