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Genetic characteristics and forensic features of Xibe ethnic group revealed via extended set of Y-STRs.
Ann Hum Biol. 2022 Jun; 49(3-4):204-209.AH

Abstract

BACKGROUND

Xibe is the fifth largest minority population of Liaoning province. Predominately they live in Liaoning province (69.52%), followed by Xinjiang (18.06%), Heilongjiang (3.99%), Jilin (1.63%) and Inner Mongolia provinces (1.57%).

AIM

To provide an updated and precise population database on an extended set of Y STRs not available before and explore the forensic characteristics of 26 Y chromosomal STRs.

SUBJECTS & METHODS

In this study, we genotyped 406 unrelated Xibe male individuals from Liaoning province using Goldeneye® 26Y System kit and calculated the forensic parameters of these 26 Y STRs loci.

RESULTS

All haplotypes generated for 406 Xibe samples using Goldeneye® 26Y kit were unique with a discrimination capacity (DC) of 1. On restricting the haplotypes to the Y-filer® set of 17 Y-STRs, we observed 392 haplotypes. Among them 93.53% (380) were unique with a DC of 0.9655 and haplotype diversity (HD) of 0.9998, showing high discrimination power of the extended set of markers in this population. Allelic frequencies ranged from 0.0024 to 0.7684 across 26 Y STRs loci. DYS385 showed the highest gene diversity (0.9691) among all markers.

CONCLUSION

According to pairwise RST genetic distances among Xibe populations from China, the Liaoning Xibe population showed the closest genetic distance (0.0035) followed by Xinjiang Xibe population (0.0218). Multidimensional scaling (MDS) analysis among Xibe and 29 other Chinese populations showed that local populations such as Manchu from Liaoning and Han from Beijing had a close affinity while Tibetans from Aba, China, were most distant from Xibe populations. Moreover, 12 individuals showed a null allele at DYS448 in Xibe population samples. We submitted Y-STRs data in the Y-Chromosome Haplotype Reference Database (YHRD) for future forensic and other usage.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Ran P
Xiamen Central Blood Station, Xiamen Blood Center, Xiamen, P.R. China.
Ou S
Xiamen Central Blood Station, Xiamen Blood Center, Xiamen, P.R. China.
Hadi S
Department of Forensic Sciences, College of Criminal Justice, Naif Arab University of Security Sciences, Riyadh, Kingdom of Saudi Arabia.
Safhi FA
Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Al-Qahtani WS
Department of Forensic Sciences, College of Criminal Justice, Naif Arab University of Security Sciences, Riyadh, Kingdom of Saudi Arabia.
Xuan JF
Department of Forensic Genetics, School of Forensic Medicine, China Medical University, Shenyang, P.R. China.
Adnan A
Department of Forensic Sciences, College of Criminal Justice, Naif Arab University of Security Sciences, Riyadh, Kingdom of Saudi Arabia.
Pei B
Xiamen Central Blood Station, Xiamen Blood Center, Xiamen, P.R. China.

MeSH

ChinaChromosomes, Human, YEthnicityGene FrequencyGenetics, PopulationHaplotypesHumansMaleMicrosatellite Repeats

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35815603

Citation

Ran, Peng, et al. "Genetic Characteristics and Forensic Features of Xibe Ethnic Group Revealed Via Extended Set of Y-STRs." Annals of Human Biology, vol. 49, no. 3-4, 2022, pp. 204-209.
Ran P, Ou S, Hadi S, et al. Genetic characteristics and forensic features of Xibe ethnic group revealed via extended set of Y-STRs. Ann Hum Biol. 2022;49(3-4):204-209.
Ran, P., Ou, S., Hadi, S., Safhi, F. A., Al-Qahtani, W. S., Xuan, J. F., Adnan, A., & Pei, B. (2022). Genetic characteristics and forensic features of Xibe ethnic group revealed via extended set of Y-STRs. Annals of Human Biology, 49(3-4), 204-209. https://doi.org/10.1080/03014460.2022.2100478
Ran P, et al. Genetic Characteristics and Forensic Features of Xibe Ethnic Group Revealed Via Extended Set of Y-STRs. Ann Hum Biol. 2022;49(3-4):204-209. PubMed PMID: 35815603.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic characteristics and forensic features of Xibe ethnic group revealed via extended set of Y-STRs. AU - Ran,Peng, AU - Ou,Shanhai, AU - Hadi,Sibte, AU - Safhi,Fatmah Ahmed, AU - Al-Qahtani,Wedad Saeed, AU - Xuan,Jin-Feng, AU - Adnan,Atif, AU - Pei,Bin, Y1 - 2022/07/26/ PY - 2022/7/12/pubmed PY - 2022/10/5/medline PY - 2022/7/11/entrez KW - Forensic genetics KW - Liaoning KW - Xibe KW - Y-Chromosome Haplotype Reference Database (YHRD) KW - Y-STRs SP - 204 EP - 209 JF - Annals of human biology JO - Ann Hum Biol VL - 49 IS - 3-4 N2 - BACKGROUND: Xibe is the fifth largest minority population of Liaoning province. Predominately they live in Liaoning province (69.52%), followed by Xinjiang (18.06%), Heilongjiang (3.99%), Jilin (1.63%) and Inner Mongolia provinces (1.57%). AIM: To provide an updated and precise population database on an extended set of Y STRs not available before and explore the forensic characteristics of 26 Y chromosomal STRs. SUBJECTS & METHODS: In this study, we genotyped 406 unrelated Xibe male individuals from Liaoning province using Goldeneye® 26Y System kit and calculated the forensic parameters of these 26 Y STRs loci. RESULTS: All haplotypes generated for 406 Xibe samples using Goldeneye® 26Y kit were unique with a discrimination capacity (DC) of 1. On restricting the haplotypes to the Y-filer® set of 17 Y-STRs, we observed 392 haplotypes. Among them 93.53% (380) were unique with a DC of 0.9655 and haplotype diversity (HD) of 0.9998, showing high discrimination power of the extended set of markers in this population. Allelic frequencies ranged from 0.0024 to 0.7684 across 26 Y STRs loci. DYS385 showed the highest gene diversity (0.9691) among all markers. CONCLUSION: According to pairwise RST genetic distances among Xibe populations from China, the Liaoning Xibe population showed the closest genetic distance (0.0035) followed by Xinjiang Xibe population (0.0218). Multidimensional scaling (MDS) analysis among Xibe and 29 other Chinese populations showed that local populations such as Manchu from Liaoning and Han from Beijing had a close affinity while Tibetans from Aba, China, were most distant from Xibe populations. Moreover, 12 individuals showed a null allele at DYS448 in Xibe population samples. We submitted Y-STRs data in the Y-Chromosome Haplotype Reference Database (YHRD) for future forensic and other usage. SN - 1464-5033 UR - https://www.unboundmedicine.com/medline/citation/35815603/Genetic_characteristics_and_forensic_features_of_Xibe_ethnic_group_revealed_via_extended_set_of_Y_STRs_ DB - PRIME DP - Unbound Medicine ER -