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Predictors of COVID-19 booster vaccine hesitancy among fully vaccinated adults in Korea: a nationwide cross-sectional survey.
Epidemiol Health. 2022; 44:e2022061.EH

Abstract

OBJECTIVES

This study explored predictors of coronavirus disease 2019 (COVID-19) booster hesitancy among fully vaccinated young adults and parental COVID-19 vaccine hesitancy for their children.

METHODS

This cross-sectional study administered an online survey from December 2 to December 20, 2021. We enrolled participants aged 18-49 years, for whom ≥2 weeks had passed after their initial COVID-19 vaccination. We estimated odds ratios (ORs) with 95% confidence intervals (CIs) using multivariate logistic regression to evaluate factors associated with booster/vaccine hesitancy.

RESULTS

Among the 2,993 participants, 48.8% showed hesitancy (wait and see: 40.2%; definitely not: 8.7%). Booster hesitancy was more common among women (OR, 1.25; 95% CI, 1.05 to 1.50), younger people (OR, 1.44; 95% CI, 1.17 to 1.77), those with a lower education level (OR, 2.05; 95% CI, 1.10 to 3.82), those who received the mRNA-1273 vaccine type (OR, 2.01; 95% CI, 1.65 to 2.45), and those who experienced serious adverse events following previous COVID-19 vaccination (OR, 2.03; 95% CI, 1.47 to 2.80). The main reasons for booster hesitancy were concerns about safety (54.1%) and doubts about efficacy (29.8%). Among the 1,020 respondents with children aged <18 years, 65.8% were hesitant to vaccinate their children against COVID-19; hesitancy was associated with younger parental age, education level, the type of vaccine the parent received, and a history of COVID-19 infection.

CONCLUSIONS

Concerns about the efficacy and safety of COVID-19 vaccines were the major barrier to booster acceptance. The initial COVID-19 vaccine type (mRNA-1273), young age, gender (women), a low education level, and adverse events after the first COVID-19 vaccine were key predictors of booster hesitancy.

Links

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Authors+Show Affiliations

Noh Y
School of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Kim JH
School of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Yoon D
School of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Choe YJ
Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea.
Choe SA
Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea. Division of Life Sciences, Korea University, Seoul, Korea.
Jung J
Department of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
Lee SW
School of Pharmacy, Sungkyunkwan University, Suwon, Korea. Department of Biohealth Regulatory Science, Sungkyunkwan University, Suwon, Korea.
Shin JY
School of Pharmacy, Sungkyunkwan University, Suwon, Korea. Department of Biohealth Regulatory Science, Sungkyunkwan University, Suwon, Korea. Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Korea.

MeSH

ChildYoung AdultFemaleHumansCOVID-19 VaccinesCross-Sectional Studies2019-nCoV Vaccine mRNA-1273Vaccination HesitancyCOVID-19Republic of Korea

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35914771

Citation

Noh, Yunha, et al. "Predictors of COVID-19 Booster Vaccine Hesitancy Among Fully Vaccinated Adults in Korea: a Nationwide Cross-sectional Survey." Epidemiology and Health, vol. 44, 2022, pp. e2022061.
Noh Y, Kim JH, Yoon D, et al. Predictors of COVID-19 booster vaccine hesitancy among fully vaccinated adults in Korea: a nationwide cross-sectional survey. Epidemiol Health. 2022;44:e2022061.
Noh, Y., Kim, J. H., Yoon, D., Choe, Y. J., Choe, S. A., Jung, J., Lee, S. W., & Shin, J. Y. (2022). Predictors of COVID-19 booster vaccine hesitancy among fully vaccinated adults in Korea: a nationwide cross-sectional survey. Epidemiology and Health, 44, e2022061. https://doi.org/10.4178/epih.e2022061
Noh Y, et al. Predictors of COVID-19 Booster Vaccine Hesitancy Among Fully Vaccinated Adults in Korea: a Nationwide Cross-sectional Survey. Epidemiol Health. 2022;44:e2022061. PubMed PMID: 35914771.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Predictors of COVID-19 booster vaccine hesitancy among fully vaccinated adults in Korea: a nationwide cross-sectional survey. AU - Noh,Yunha, AU - Kim,Ju Hwan, AU - Yoon,Dongwon, AU - Choe,Young June, AU - Choe,Seung-Ah, AU - Jung,Jaehun, AU - Lee,Sang-Won, AU - Shin,Ju-Young, Y1 - 2022/07/22/ PY - 2022/3/30/received PY - 2022/7/22/accepted PY - 2022/8/2/pubmed PY - 2022/12/20/medline PY - 2022/8/1/entrez KW - Coronavirus KW - Immunization KW - Public health KW - Vaccine hesitancy SP - e2022061 EP - e2022061 JF - Epidemiology and health JO - Epidemiol Health VL - 44 N2 - OBJECTIVES: This study explored predictors of coronavirus disease 2019 (COVID-19) booster hesitancy among fully vaccinated young adults and parental COVID-19 vaccine hesitancy for their children. METHODS: This cross-sectional study administered an online survey from December 2 to December 20, 2021. We enrolled participants aged 18-49 years, for whom ≥2 weeks had passed after their initial COVID-19 vaccination. We estimated odds ratios (ORs) with 95% confidence intervals (CIs) using multivariate logistic regression to evaluate factors associated with booster/vaccine hesitancy. RESULTS: Among the 2,993 participants, 48.8% showed hesitancy (wait and see: 40.2%; definitely not: 8.7%). Booster hesitancy was more common among women (OR, 1.25; 95% CI, 1.05 to 1.50), younger people (OR, 1.44; 95% CI, 1.17 to 1.77), those with a lower education level (OR, 2.05; 95% CI, 1.10 to 3.82), those who received the mRNA-1273 vaccine type (OR, 2.01; 95% CI, 1.65 to 2.45), and those who experienced serious adverse events following previous COVID-19 vaccination (OR, 2.03; 95% CI, 1.47 to 2.80). The main reasons for booster hesitancy were concerns about safety (54.1%) and doubts about efficacy (29.8%). Among the 1,020 respondents with children aged <18 years, 65.8% were hesitant to vaccinate their children against COVID-19; hesitancy was associated with younger parental age, education level, the type of vaccine the parent received, and a history of COVID-19 infection. CONCLUSIONS: Concerns about the efficacy and safety of COVID-19 vaccines were the major barrier to booster acceptance. The initial COVID-19 vaccine type (mRNA-1273), young age, gender (women), a low education level, and adverse events after the first COVID-19 vaccine were key predictors of booster hesitancy. SN - 2092-7193 UR - https://www.unboundmedicine.com/medline/citation/35914771/Predictors_of_COVID_19_booster_vaccine_hesitancy_among_fully_vaccinated_adults_in_Korea:_a_nationwide_cross_sectional_survey_ DB - PRIME DP - Unbound Medicine ER -