Tags

Type your tag names separated by a space and hit enter

Serum-"free"-thyroxine and triiodothyronine levels: their significance in preclinical hyperthyroidism and subclinical hypothyroidism.
Acta Med Hung 1986; 43(4):373-80AM

Abstract

A study was performed to establish whether the serum-"free" T4 and T3 levels contributed to the diagnosis of latent thyroid disease. The results suggested that in case of autonomous adenoma an increase in the serum free T3-level is the most reliable indicator of the transformation of the thyroid nodule, and that this hormone concentration, in addition to the TSH--IRMA procedure contributed to the differentiation between euthyroid and hyperthyroid state. In subclinical hypothyroidism, regarded as a heterogeneous subgroup, the mean "free" T4 levels, though still within the normal range, were below those of the controls. Measurement of "free" T4 alone was, however, not sufficient for the diagnosis of subclinical hypothyroidism, but contributed to the differentiation of subclinical from manifest hypothyroidism. Subclinical hypothyroidism raised the possibility that a reduction in the serum hormone levels, though still within the normal limits, may be perceived by the peripheral tissues. Preliminary studies indicated that measurement of the systolic time interval may offer information on this issue.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3601583

Citation

Földes, J, et al. "Serum-"free"-thyroxine and Triiodothyronine Levels: Their Significance in Preclinical Hyperthyroidism and Subclinical Hypothyroidism." Acta Medica Hungarica, vol. 43, no. 4, 1986, pp. 373-80.
Földes J, Bános C, Lakatos P, et al. Serum-"free"-thyroxine and triiodothyronine levels: their significance in preclinical hyperthyroidism and subclinical hypothyroidism. Acta Med Hung. 1986;43(4):373-80.
Földes, J., Bános, C., Lakatos, P., Váradi, A., Gara, A., & Istvánffy, M. (1986). Serum-"free"-thyroxine and triiodothyronine levels: their significance in preclinical hyperthyroidism and subclinical hypothyroidism. Acta Medica Hungarica, 43(4), pp. 373-80.
Földes J, et al. Serum-"free"-thyroxine and Triiodothyronine Levels: Their Significance in Preclinical Hyperthyroidism and Subclinical Hypothyroidism. Acta Med Hung. 1986;43(4):373-80. PubMed PMID: 3601583.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum-"free"-thyroxine and triiodothyronine levels: their significance in preclinical hyperthyroidism and subclinical hypothyroidism. AU - Földes,J, AU - Bános,C, AU - Lakatos,P, AU - Váradi,A, AU - Gara,A, AU - Istvánffy,M, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 373 EP - 80 JF - Acta medica Hungarica JO - Acta Med Hung VL - 43 IS - 4 N2 - A study was performed to establish whether the serum-"free" T4 and T3 levels contributed to the diagnosis of latent thyroid disease. The results suggested that in case of autonomous adenoma an increase in the serum free T3-level is the most reliable indicator of the transformation of the thyroid nodule, and that this hormone concentration, in addition to the TSH--IRMA procedure contributed to the differentiation between euthyroid and hyperthyroid state. In subclinical hypothyroidism, regarded as a heterogeneous subgroup, the mean "free" T4 levels, though still within the normal range, were below those of the controls. Measurement of "free" T4 alone was, however, not sufficient for the diagnosis of subclinical hypothyroidism, but contributed to the differentiation of subclinical from manifest hypothyroidism. Subclinical hypothyroidism raised the possibility that a reduction in the serum hormone levels, though still within the normal limits, may be perceived by the peripheral tissues. Preliminary studies indicated that measurement of the systolic time interval may offer information on this issue. SN - 0236-5286 UR - https://www.unboundmedicine.com/medline/citation/3601583/Serum_"free"_thyroxine_and_triiodothyronine_levels:_their_significance_in_preclinical_hyperthyroidism_and_subclinical_hypothyroidism_ L2 - https://medlineplus.gov/hyperthyroidism.html DB - PRIME DP - Unbound Medicine ER -