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Genome-wide association study reveals distinct genetic associations related to leaf hair density in two lineages of wheat-wild relative Aegilops tauschii.
Sci Rep. 2022 10 19; 12(1):17486.SR

Abstract

Wild relatives of modern crops represent a promising source of genetic variation that can be mined for adaptations to climate change. Aegilops tauschii, the D-sub-genome progenitor of bread wheat (Triticum aestivum), constitutes a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Leaf hairiness plays an essential biological role in plant defense against biotic and abiotic stress. We investigated the natural variation in leaf hair density (LHD) among 293 Ae. tauschii accessions. Genome-wide association studies were performed for LHD with 2430 and 3880 DArTseq derived single nucleotide polymorphism (SNP) markers in two lineages of this species, TauL1 and TauL2, respectively. In TauL1, three marker-trait associations (MTAs) were located on chromosome 2D, whereas in TauL2, eight MTAs were identified, two associations were localized on each of the chromosomes 2D, 3D, 5D, and 7D. The markers explained phenotypic variation (R2) from 9 to 13% in TauL1 and 11 to 36% in TauL2. The QTLs identified in chromosomes 2D and 5D might be novel. Our results revealed more rapid and independent evolution of LHD in TauL2 compared to TauL1. The majority of LHD candidate genes identified are associated with biotic and abiotic stress responses. This study highlights the significance of intraspecific diversity of Ae. tauschii to enhance cultivated wheat germplasm.

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Authors+Show Affiliations

Mahjoob MMM
United Graduate School of Agricultural Sciences, Tottori University, Tottori, 680-8553, Japan. Wheat Research Program, Agricultural Research Corporation, P.O. Box 126, Wad Medani, Sudan.
Kamal NM
Wheat Research Program, Agricultural Research Corporation, P.O. Box 126, Wad Medani, Sudan. Arid Land Research Center, Tottori University, Tottori, 680-0001, Japan.
Gorafi YSA
Wheat Research Program, Agricultural Research Corporation, P.O. Box 126, Wad Medani, Sudan. Arid Land Research Center, Tottori University, Tottori, 680-0001, Japan.
Tsujimoto H
Arid Land Research Center, Tottori University, Tottori, 680-0001, Japan. tsujim@tottori-u.ac.jp.

MeSH

AegilopsTriticumGenome-Wide Association StudyQuantitative Trait LociPlant Leaves

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

36261481

Citation

Mahjoob, Mazin Mahjoob Mohamed, et al. "Genome-wide Association Study Reveals Distinct Genetic Associations Related to Leaf Hair Density in Two Lineages of Wheat-wild Relative Aegilops Tauschii." Scientific Reports, vol. 12, no. 1, 2022, p. 17486.
Mahjoob MMM, Kamal NM, Gorafi YSA, et al. Genome-wide association study reveals distinct genetic associations related to leaf hair density in two lineages of wheat-wild relative Aegilops tauschii. Sci Rep. 2022;12(1):17486.
Mahjoob, M. M. M., Kamal, N. M., Gorafi, Y. S. A., & Tsujimoto, H. (2022). Genome-wide association study reveals distinct genetic associations related to leaf hair density in two lineages of wheat-wild relative Aegilops tauschii. Scientific Reports, 12(1), 17486. https://doi.org/10.1038/s41598-022-21713-3
Mahjoob MMM, et al. Genome-wide Association Study Reveals Distinct Genetic Associations Related to Leaf Hair Density in Two Lineages of Wheat-wild Relative Aegilops Tauschii. Sci Rep. 2022 10 19;12(1):17486. PubMed PMID: 36261481.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genome-wide association study reveals distinct genetic associations related to leaf hair density in two lineages of wheat-wild relative Aegilops tauschii. AU - Mahjoob,Mazin Mahjoob Mohamed, AU - Kamal,Nasrein Mohamed, AU - Gorafi,Yasir Serag Alnor, AU - Tsujimoto,Hisashi, Y1 - 2022/10/19/ PY - 2022/05/18/received PY - 2022/09/30/accepted PY - 2022/10/19/entrez PY - 2022/10/20/pubmed PY - 2022/10/22/medline SP - 17486 EP - 17486 JF - Scientific reports JO - Sci Rep VL - 12 IS - 1 N2 - Wild relatives of modern crops represent a promising source of genetic variation that can be mined for adaptations to climate change. Aegilops tauschii, the D-sub-genome progenitor of bread wheat (Triticum aestivum), constitutes a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Leaf hairiness plays an essential biological role in plant defense against biotic and abiotic stress. We investigated the natural variation in leaf hair density (LHD) among 293 Ae. tauschii accessions. Genome-wide association studies were performed for LHD with 2430 and 3880 DArTseq derived single nucleotide polymorphism (SNP) markers in two lineages of this species, TauL1 and TauL2, respectively. In TauL1, three marker-trait associations (MTAs) were located on chromosome 2D, whereas in TauL2, eight MTAs were identified, two associations were localized on each of the chromosomes 2D, 3D, 5D, and 7D. The markers explained phenotypic variation (R2) from 9 to 13% in TauL1 and 11 to 36% in TauL2. The QTLs identified in chromosomes 2D and 5D might be novel. Our results revealed more rapid and independent evolution of LHD in TauL2 compared to TauL1. The majority of LHD candidate genes identified are associated with biotic and abiotic stress responses. This study highlights the significance of intraspecific diversity of Ae. tauschii to enhance cultivated wheat germplasm. SN - 2045-2322 UR - https://www.unboundmedicine.com/medline/citation/36261481/Genome_wide_association_study_reveals_distinct_genetic_associations_related_to_leaf_hair_density_in_two_lineages_of_wheat_wild_relative_Aegilops_tauschii_ DB - PRIME DP - Unbound Medicine ER -