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[Auricular point sticking combined with transcutaneous electrical acupoint stimulation for smoking cessation：a randomized controlled trial].
Zhongguo Zhen Jiu. 2022 Nov 12; 42(11):1235-9.ZZ

Abstract

OBJECTIVE

To compare the clinical efficacy between auricular point sticking combined with transcutaneous electrical acupoint stimulation (TEAS) and nicotine patch for smoking cessation.

METHODS

Two hundred patients who voluntarily quit smoking were randomly divided into a combination group and a nicotine patch group, 100 cases in each group. In the combination group, auricular point sticking (Shenmen [TF4], Neifenmi [CO18], Pizhixia [AT4], Jiaogan [AH6a], etc., once every other day) combined with TEAS（Lieque [LU 7] and Zusanli [ST 36], with continuous wave, 20 Hz in frequency, 1 mA in current intensity, 30 min each time, once a day) were applied. In the nicotine patch group, nicotine patch was applied. Both groups were treated for 8 weeks. The immediate withdrawal rate and persistent withdrawal rate 8 weeks into treatment and in follow-up of 16 weeks after treatment in the two groups were compared; before treatment, 8 weeks into treatment and in follow-up of 16 weeks after treatment, the degree of nicotine dependence was evaluated by using Fagerström test for nicotine dependence (FTND); 1 week into treatment, 8 weeks into treatment and in follow-up of 16 weeks after treatment, the withdrawal symptoms and smoking craving were evaluated by using Minnesota nicotine withdrawal scale (MNWS); the safety and compliance (dropped off rate and treatment completeness) were evaluated in the two groups.

RESULTS

There was no statistical significance of the differences in the immediate withdrawal rate and persistent withdrawal rate 8 weeks into treatment and during follow-up between the two groups (P>0.05). The FTND scores were decreased 8 weeks into treatment and during follow-up in the two groups compared with those before treatment (P<0.01); the FTND score during follow-up in the combination group was lower than the nicotine patch group (P<0.05). The MNWS scores were decreased 8 weeks into treatment and during follow-up in the two groups compared with those 1 week into treatment (P<0.05); the changes of MNWS scores 8 weeks into treatment and during follow-up in the combination group were greater than the nicotine patch group (P<0.05, P<0.01). There were no serious adverse reactions in either group. Eight weeks into treatment and during follow-up, the dropped off rates were all 16.0% (16/100) in the combination group, which were 20.0% (20/100) and 23.0% (23/100) in the nicotine patch group, there was no statistical significance of the differences in the two groups (P>0.05). There was no significant difference in treatment completeness between the two groups (P>0.05).

CONCLUSION

Auricular point sticking combined with TEAS could effective decrease the degree of nicotine dependence, improve withdrawal symptoms in smokers, its effect is superior to nicotine patch.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Chen SM
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Liu ZY
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Ji J
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Liu Z
Tobacco Medicine and Tobacco Cessation Center, China-Japan Friendship Hospital.
Wang YY
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yang JS
Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences.

MeSH

HumansSmoking CessationTobacco Use DisorderAcupuncture PointsAdministration, CutaneousNicotineSubstance Withdrawal Syndrome

Pub Type(s)

Randomized Controlled Trial
English Abstract
Journal Article

Language

chi

PubMed ID

36397220

Citation

Chen, Shu-Min, et al. "[Auricular Point Sticking Combined With Transcutaneous Electrical Acupoint Stimulation for Smoking Cessation：a Randomized Controlled Trial]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 42, no. 11, 2022, pp. 1235-9.
Chen SM, Liu ZY, Ji J, et al. [Auricular point sticking combined with transcutaneous electrical acupoint stimulation for smoking cessation：a randomized controlled trial]. Zhongguo Zhen Jiu. 2022;42(11):1235-9.
Chen, S. M., Liu, Z. Y., Ji, J., Liu, Z., Wang, Y. Y., & Yang, J. S. (2022). [Auricular point sticking combined with transcutaneous electrical acupoint stimulation for smoking cessation：a randomized controlled trial]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 42(11), 1235-9. https://doi.org/10.13703/j.0255-2930.20220104-k0001
Chen SM, et al. [Auricular Point Sticking Combined With Transcutaneous Electrical Acupoint Stimulation for Smoking Cessation：a Randomized Controlled Trial]. Zhongguo Zhen Jiu. 2022 Nov 12;42(11):1235-9. PubMed PMID: 36397220.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Auricular point sticking combined with transcutaneous electrical acupoint stimulation for smoking cessation：a randomized controlled trial]. AU - Chen,Shu-Min, AU - Liu,Zhen-Yu, AU - Ji,Jia, AU - Liu,Zhao, AU - Wang,Ying-Ying, AU - Yang,Jin-Sheng, PY - 2022/11/18/entrez PY - 2022/11/19/pubmed PY - 2022/11/22/medline KW - auricular point sticking KW - nicotine patch KW - randomized controlled trial (RCT) KW - smoking cessation KW - transcutaneous electrical acupoint stimulation (TEAS) KW - withdrawal rate SP - 1235 EP - 9 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 42 IS - 11 N2 - OBJECTIVE: To compare the clinical efficacy between auricular point sticking combined with transcutaneous electrical acupoint stimulation (TEAS) and nicotine patch for smoking cessation. METHODS: Two hundred patients who voluntarily quit smoking were randomly divided into a combination group and a nicotine patch group, 100 cases in each group. In the combination group, auricular point sticking (Shenmen [TF4], Neifenmi [CO18], Pizhixia [AT4], Jiaogan [AH6a], etc., once every other day) combined with TEAS（Lieque [LU 7] and Zusanli [ST 36], with continuous wave, 20 Hz in frequency, 1 mA in current intensity, 30 min each time, once a day) were applied. In the nicotine patch group, nicotine patch was applied. Both groups were treated for 8 weeks. The immediate withdrawal rate and persistent withdrawal rate 8 weeks into treatment and in follow-up of 16 weeks after treatment in the two groups were compared; before treatment, 8 weeks into treatment and in follow-up of 16 weeks after treatment, the degree of nicotine dependence was evaluated by using Fagerström test for nicotine dependence (FTND); 1 week into treatment, 8 weeks into treatment and in follow-up of 16 weeks after treatment, the withdrawal symptoms and smoking craving were evaluated by using Minnesota nicotine withdrawal scale (MNWS); the safety and compliance (dropped off rate and treatment completeness) were evaluated in the two groups. RESULTS: There was no statistical significance of the differences in the immediate withdrawal rate and persistent withdrawal rate 8 weeks into treatment and during follow-up between the two groups (P>0.05). The FTND scores were decreased 8 weeks into treatment and during follow-up in the two groups compared with those before treatment (P<0.01); the FTND score during follow-up in the combination group was lower than the nicotine patch group (P<0.05). The MNWS scores were decreased 8 weeks into treatment and during follow-up in the two groups compared with those 1 week into treatment (P<0.05); the changes of MNWS scores 8 weeks into treatment and during follow-up in the combination group were greater than the nicotine patch group (P<0.05, P<0.01). There were no serious adverse reactions in either group. Eight weeks into treatment and during follow-up, the dropped off rates were all 16.0% (16/100) in the combination group, which were 20.0% (20/100) and 23.0% (23/100) in the nicotine patch group, there was no statistical significance of the differences in the two groups (P>0.05). There was no significant difference in treatment completeness between the two groups (P>0.05). CONCLUSION: Auricular point sticking combined with TEAS could effective decrease the degree of nicotine dependence, improve withdrawal symptoms in smokers, its effect is superior to nicotine patch. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/36397220/[Auricular_point_sticking_combined_with_transcutaneous_electrical_acupoint_stimulation_for_smoking_cessation：a_randomized_controlled_trial]_ DB - PRIME DP - Unbound Medicine ER -