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Post-vaccination adverse reactions, decision regret, and willingness to pay for the booster dose of COVID-19 vaccine among healthcare workers: A mediation analysis.
Hum Vaccin Immunother. 2022 Nov 30; 18(6):2146964.HV

Abstract

This study aimed to explore the relationship between post-vaccination adverse reactions, decision regret, and willingness to pay (WTP) for the booster dose. An online survey was conducted in Taizhou, China. Questionnaires were completed by 1,085 healthcare workers (HCWs) and 1,054 (97.1%) have received two doses of the COVID-19 vaccine. Mediation analysis method was adopted. Our study presented that post-vaccination adverse reactions in HCWs could decrease their WTP for the booster dose. Of note, HCWs experienced adverse reactions after vaccination would more likely regret their previous vaccination decisions, which, in turn, further reduced their WTP for a booster shot. Decision regret mediated the relationship between adverse post-vaccination reactions and WTP for the booster dose. The findings implied inextricable relationships among post-vaccination adverse reactions, decision regret, and WTP of the booster dose. It suggested that these post-vaccination adverse reactions should be further incorporated into vaccine campaigns to improve vaccine intention and potentially increase willingness to pay for booster doses of COVID-19 vaccine.

Authors+Show Affiliations

Evidence-based Medicine Center, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Linhai, China.Department of Information Technology, Linhai Rural Commercial Bank, Linhai, China.Department of Orthopedics, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang, China.Evidence-based Medicine Center, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Linhai, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

36422511

Citation

Luo, Chengwen, et al. "Post-vaccination Adverse Reactions, Decision Regret, and Willingness to Pay for the Booster Dose of COVID-19 Vaccine Among Healthcare Workers: a Mediation Analysis." Human Vaccines & Immunotherapeutics, vol. 18, no. 6, 2022, p. 2146964.
Luo C, Jiang W, Chen HX, et al. Post-vaccination adverse reactions, decision regret, and willingness to pay for the booster dose of COVID-19 vaccine among healthcare workers: A mediation analysis. Hum Vaccin Immunother. 2022;18(6):2146964.
Luo, C., Jiang, W., Chen, H. X., & Tung, T. H. (2022). Post-vaccination adverse reactions, decision regret, and willingness to pay for the booster dose of COVID-19 vaccine among healthcare workers: A mediation analysis. Human Vaccines & Immunotherapeutics, 18(6), 2146964. https://doi.org/10.1080/21645515.2022.2146964
Luo C, et al. Post-vaccination Adverse Reactions, Decision Regret, and Willingness to Pay for the Booster Dose of COVID-19 Vaccine Among Healthcare Workers: a Mediation Analysis. Hum Vaccin Immunother. 2022 Nov 30;18(6):2146964. PubMed PMID: 36422511.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Post-vaccination adverse reactions, decision regret, and willingness to pay for the booster dose of COVID-19 vaccine among healthcare workers: A mediation analysis. AU - Luo,Chengwen, AU - Jiang,Weicong, AU - Chen,Hai-Xiao, AU - Tung,Tao-Hsin, Y1 - 2022/11/24/ PY - 2022/11/25/pubmed PY - 2022/12/15/medline PY - 2022/11/24/entrez KW - COVID-19 booster vaccine KW - Healthcare workers KW - decision regret KW - vaccination adverse reaction KW - willingness-to-pay SP - 2146964 EP - 2146964 JF - Human vaccines & immunotherapeutics JO - Hum Vaccin Immunother VL - 18 IS - 6 N2 - This study aimed to explore the relationship between post-vaccination adverse reactions, decision regret, and willingness to pay (WTP) for the booster dose. An online survey was conducted in Taizhou, China. Questionnaires were completed by 1,085 healthcare workers (HCWs) and 1,054 (97.1%) have received two doses of the COVID-19 vaccine. Mediation analysis method was adopted. Our study presented that post-vaccination adverse reactions in HCWs could decrease their WTP for the booster dose. Of note, HCWs experienced adverse reactions after vaccination would more likely regret their previous vaccination decisions, which, in turn, further reduced their WTP for a booster shot. Decision regret mediated the relationship between adverse post-vaccination reactions and WTP for the booster dose. The findings implied inextricable relationships among post-vaccination adverse reactions, decision regret, and WTP of the booster dose. It suggested that these post-vaccination adverse reactions should be further incorporated into vaccine campaigns to improve vaccine intention and potentially increase willingness to pay for booster doses of COVID-19 vaccine. SN - 2164-554X UR - https://www.unboundmedicine.com/medline/citation/36422511/Post_vaccination_adverse_reactions_decision_regret_and_willingness_to_pay_for_the_booster_dose_of_COVID_19_vaccine_among_healthcare_workers:_A_mediation_analysis_ DB - PRIME DP - Unbound Medicine ER -