Armochaetoglasins L and M, new cytochalasans from an arthropod-derived fungus Chaetomium globosum.Nat Prod Res. 2022 Nov 28 [Online ahead of print]NP
Abstract
Armochaetoglasins L (1) and M (2), two new cytochalasans, were isolated from the EtOAc extract of an arthropod-derived fungus Chaetomium globosum. Armochaetoglasin L (1) is a rare 19,20-seco-chaetoglobosin. Their structures were elucidated by NMR spectroscopy and comparison of their electronic circular dichroism (ECD) data. Compounds 1 and 2 were evaluated for anti-inflammatory activity against the NO production by using LPS-stimulated murine macrophage RAW264.7 cells and antibacterial activity against three drug-resistant microbial pathogens.
Links
Pub Type(s)
Journal Article
Language
eng
PubMed ID
36441184
Citation
Gao, Weixi, et al. "Armochaetoglasins L and M, New Cytochalasans From an Arthropod-derived Fungus Chaetomium Globosum." Natural Product Research, 2022, pp. 1-7.
Gao W, Jiang R, Zeng H, et al. Armochaetoglasins L and M, new cytochalasans from an arthropod-derived fungus Chaetomium globosum. Nat Prod Res. 2022.
Gao, W., Jiang, R., Zeng, H., Cao, J., Hu, Z., & Zhang, Y. (2022). Armochaetoglasins L and M, new cytochalasans from an arthropod-derived fungus Chaetomium globosum. Natural Product Research, 1-7. https://doi.org/10.1080/14786419.2022.2150846
Gao W, et al. Armochaetoglasins L and M, New Cytochalasans From an Arthropod-derived Fungus Chaetomium Globosum. Nat Prod Res. 2022 Nov 28;1-7. PubMed PMID: 36441184.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Armochaetoglasins L and M, new cytochalasans from an arthropod-derived fungus Chaetomium globosum.
AU - Gao,Weixi,
AU - Jiang,Rui,
AU - Zeng,Hanxiao,
AU - Cao,Jie,
AU - Hu,Zhengxi,
AU - Zhang,Yonghui,
Y1 - 2022/11/28/
PY - 2022/11/28/entrez
PY - 2022/11/29/pubmed
PY - 2022/11/29/medline
KW - Chaetomium globosum
KW - anti-inflammatory activity
KW - antibacterial activity
KW - cytochalasans
KW - structure elucidation
SP - 1
EP - 7
JF - Natural product research
JO - Nat Prod Res
N2 - Armochaetoglasins L (1) and M (2), two new cytochalasans, were isolated from the EtOAc extract of an arthropod-derived fungus Chaetomium globosum. Armochaetoglasin L (1) is a rare 19,20-seco-chaetoglobosin. Their structures were elucidated by NMR spectroscopy and comparison of their electronic circular dichroism (ECD) data. Compounds 1 and 2 were evaluated for anti-inflammatory activity against the NO production by using LPS-stimulated murine macrophage RAW264.7 cells and antibacterial activity against three drug-resistant microbial pathogens.
SN - 1478-6427
UR - https://www.unboundmedicine.com/medline/citation/36441184/Armochaetoglasins_L_and_M_new_cytochalasans_from_an_arthropod_derived_fungus_Chaetomium_globosum_
DB - PRIME
DP - Unbound Medicine
ER -
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