Tags

Type your tag names separated by a space and hit enter

Relationship between high fructose corn syrup sweetened drinks, diet soft drinks, and serum sodium: NHANES 2003-2006.
Nutr J. 2022 12 29; 21(1):76.NJ

Abstract

BACKGROUND

Consumption of high fructose corn syrup sweetened drinks and diet soft drinks has increased in the United States. However, the relationship between the intake of high fructose corn syrup sweetened drinks and diet soft drinks, and serum sodium has been scarcely studied. Our objective is to evaluate the relation between intake of high fructose corn syrup sweetened drinks and diet soft drinks, and serum sodium, and explore the possible effect modifiers in a nationally representative sample of adults from the United States.

METHODS

We conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey 2003-2006. The study participants included 6989 adults aged ≥18 years. Using survey-weighted generalized linear regression analyses, we investigated the relationship between high fructose corn syrup sweetened drink, diet soft drink consumption, and serum sodium. Consumption of high fructose corn syrup sweetened drinks and diet soft drinks was evaluated through a food-frequency questionnaire.

RESULTS

Serum sodium levels increased as high fructose corn syrup sweetened drink intake increased. Serum sodium levels were higher in participants in the highest high fructose corn syrup sweetened drink consumption quantile, compared with those in the lowest high fructose corn syrup sweetened drink intake quantile (p = 0.020). The multivariate betas for serum sodium, according to the corresponding high fructose corn syrup sweetened drink intake quantiles, were 0.16, 0.19, and 0.21, respectively (P for trend = 0.051). We found no relationship between diet soft drink consumption and serum sodium after adjustment of confounding. (multivariate P > 0.05).

CONCLUSION

There was a a step-wise increase in serum sodium concentration with increasing consumption of HFCS sweetened beverages. Even moderate HFCS sweetened soft drink intake was associated with an elevated serum sodium level - a risk factor for hypertension.

Links

PMC Free PDF

Authors+Show Affiliations

Li M
Department of Traditional Chinese Medicine, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang Badachu, Shijingshan District, Beijing, 100144, China.
Gong W
Department of Traditional Chinese Medicine, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang Badachu, Shijingshan District, Beijing, 100144, China.
Wang S
Department of Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No.5 Haiyuncang, Dongcheng District, Beijing, 100700, China.
Li Z
Department of Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No.5 Haiyuncang, Dongcheng District, Beijing, 100700, China. lizhetcm@126.com.

MeSH

AdultHumansUnited StatesAdolescentHigh Fructose Corn SyrupSugar-Sweetened BeveragesNutrition SurveysCross-Sectional StudiesDietCarbonated BeveragesFructoseBeverages

Pub Type(s)

Journal Article

Language

eng

PubMed ID

36581871

Citation

Li, Mingxi, et al. "Relationship Between High Fructose Corn Syrup Sweetened Drinks, Diet Soft Drinks, and Serum Sodium: NHANES 2003-2006." Nutrition Journal, vol. 21, no. 1, 2022, p. 76.
Li M, Gong W, Wang S, et al. Relationship between high fructose corn syrup sweetened drinks, diet soft drinks, and serum sodium: NHANES 2003-2006. Nutr J. 2022;21(1):76.
Li, M., Gong, W., Wang, S., & Li, Z. (2022). Relationship between high fructose corn syrup sweetened drinks, diet soft drinks, and serum sodium: NHANES 2003-2006. Nutrition Journal, 21(1), 76. https://doi.org/10.1186/s12937-022-00832-7
Li M, et al. Relationship Between High Fructose Corn Syrup Sweetened Drinks, Diet Soft Drinks, and Serum Sodium: NHANES 2003-2006. Nutr J. 2022 12 29;21(1):76. PubMed PMID: 36581871.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between high fructose corn syrup sweetened drinks, diet soft drinks, and serum sodium: NHANES 2003-2006. AU - Li,Mingxi, AU - Gong,Weijun, AU - Wang,Shidong, AU - Li,Zhe, Y1 - 2022/12/29/ PY - 2022/02/15/received PY - 2022/12/26/accepted PY - 2022/12/29/entrez PY - 2022/12/30/pubmed PY - 2023/1/3/medline KW - A cross-sectional study KW - Artificially sweetened beverages KW - Fructose and hypertension KW - High fructose corn syrup sweetened beverages KW - Regression analysis KW - Serum sodium SP - 76 EP - 76 JF - Nutrition journal JO - Nutr J VL - 21 IS - 1 N2 - BACKGROUND: Consumption of high fructose corn syrup sweetened drinks and diet soft drinks has increased in the United States. However, the relationship between the intake of high fructose corn syrup sweetened drinks and diet soft drinks, and serum sodium has been scarcely studied. Our objective is to evaluate the relation between intake of high fructose corn syrup sweetened drinks and diet soft drinks, and serum sodium, and explore the possible effect modifiers in a nationally representative sample of adults from the United States. METHODS: We conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey 2003-2006. The study participants included 6989 adults aged ≥18 years. Using survey-weighted generalized linear regression analyses, we investigated the relationship between high fructose corn syrup sweetened drink, diet soft drink consumption, and serum sodium. Consumption of high fructose corn syrup sweetened drinks and diet soft drinks was evaluated through a food-frequency questionnaire. RESULTS: Serum sodium levels increased as high fructose corn syrup sweetened drink intake increased. Serum sodium levels were higher in participants in the highest high fructose corn syrup sweetened drink consumption quantile, compared with those in the lowest high fructose corn syrup sweetened drink intake quantile (p = 0.020). The multivariate betas for serum sodium, according to the corresponding high fructose corn syrup sweetened drink intake quantiles, were 0.16, 0.19, and 0.21, respectively (P for trend = 0.051). We found no relationship between diet soft drink consumption and serum sodium after adjustment of confounding. (multivariate P > 0.05). CONCLUSION: There was a a step-wise increase in serum sodium concentration with increasing consumption of HFCS sweetened beverages. Even moderate HFCS sweetened soft drink intake was associated with an elevated serum sodium level - a risk factor for hypertension. SN - 1475-2891 UR - https://www.unboundmedicine.com/medline/citation/36581871/Relationship_between_high_fructose_corn_syrup_sweetened_drinks_diet_soft_drinks_and_serum_sodium:_NHANES_2003_2006_ DB - PRIME DP - Unbound Medicine ER -