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Complement and sepsis.
Allergol Immunopathol (Madr). 1987 May-Jun; 15(3):145-9.AI

Abstract

The present study is an evaluation of changes undergone in the serum of factors C3 and C4 of the complement, IgG, IgA, IgM and circulating immune complexes during the initial phase of sepsis and throughout its development in 53 patients, with the object of establishing their prognostic value. During the initial phase of sepsis the determination of the serum levels of immunoglobulins (IgG, IgA, IgM), C3 and C4 complement components and circulating immune complexes lack prognostic interest. Nevertheless, the disappearance of circulating immune complexes, together with an intensive reduction in concentration of IgG, IgM, and C3 and C4 complement components below the range of normality, during the evolutive course, is an indication of a bad prognosis.

Authors+Show Affiliations

Department of Microbiology, University of Granada, Spain.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3661354

Citation

Gutiérrez-Fernández, J, et al. "Complement and Sepsis." Allergologia Et Immunopathologia, vol. 15, no. 3, 1987, pp. 145-9.
Gutiérrez-Fernández J, Maroto MC, Piédrola G, et al. Complement and sepsis. Allergol Immunopathol (Madr). 1987;15(3):145-9.
Gutiérrez-Fernández, J., Maroto, M. C., Piédrola, G., & Zamora, E. (1987). Complement and sepsis. Allergologia Et Immunopathologia, 15(3), 145-9.
Gutiérrez-Fernández J, et al. Complement and Sepsis. Allergol Immunopathol (Madr). 1987 May-Jun;15(3):145-9. PubMed PMID: 3661354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Complement and sepsis. AU - Gutiérrez-Fernández,J, AU - Maroto,M C, AU - Piédrola,G, AU - Zamora,E, PY - 1987/5/1/pubmed PY - 1987/5/1/medline PY - 1987/5/1/entrez SP - 145 EP - 9 JF - Allergologia et immunopathologia JO - Allergol Immunopathol (Madr) VL - 15 IS - 3 N2 - The present study is an evaluation of changes undergone in the serum of factors C3 and C4 of the complement, IgG, IgA, IgM and circulating immune complexes during the initial phase of sepsis and throughout its development in 53 patients, with the object of establishing their prognostic value. During the initial phase of sepsis the determination of the serum levels of immunoglobulins (IgG, IgA, IgM), C3 and C4 complement components and circulating immune complexes lack prognostic interest. Nevertheless, the disappearance of circulating immune complexes, together with an intensive reduction in concentration of IgG, IgM, and C3 and C4 complement components below the range of normality, during the evolutive course, is an indication of a bad prognosis. SN - 0301-0546 UR - https://www.unboundmedicine.com/medline/citation/3661354/Complement_and_sepsis_ DB - PRIME DP - Unbound Medicine ER -