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Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report.
Heliyon. 2023 Jan; 9(1):e12761.H

Abstract

We report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed a parenchymal mass with speculation and pleural invasion in his left lung. The patient was initially diagnosed with brain metastases from lung cancer and underwent a craniotomy. Many fungal hyphae were found in the left parietal lesion, and the final pathological diagnosis of intracranial mucormycosis. After craniotomy and an entire course of treatment with liposomal amphotericin B, the patient was completely cured of both intracranial and pulmonary occupying lesions. We hope that this case experience will help expand neurosurgeons' differential diagnosis and treatment of such diseases.

Authors+Show Affiliations

Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR China.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

36685477

Citation

Cai, Yuankun, et al. "Cerebral Mucormycosis Masquerading as Brain Metastasis From Lung Cancer: a Case Report." Heliyon, vol. 9, no. 1, 2023, pp. e12761.
Cai Y, Wu Q, Wu X, et al. Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report. Heliyon. 2023;9(1):e12761.
Cai, Y., Wu, Q., Wu, X., & Liu, Z. (2023). Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report. Heliyon, 9(1), e12761. https://doi.org/10.1016/j.heliyon.2022.e12761
Cai Y, et al. Cerebral Mucormycosis Masquerading as Brain Metastasis From Lung Cancer: a Case Report. Heliyon. 2023;9(1):e12761. PubMed PMID: 36685477.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report. AU - Cai,Yuankun, AU - Wu,Qian, AU - Wu,Xiaohui, AU - Liu,Zheng, Y1 - 2022/12/30/ PY - 2022/05/25/received PY - 2022/11/23/revised PY - 2022/12/28/accepted PY - 2023/1/23/entrez PY - 2023/1/24/pubmed PY - 2023/1/24/medline KW - Case report KW - Fungal infections KW - Misdiagnosis KW - Mucormycosis KW - Ring enhancement SP - e12761 EP - e12761 JF - Heliyon JO - Heliyon VL - 9 IS - 1 N2 - We report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed a parenchymal mass with speculation and pleural invasion in his left lung. The patient was initially diagnosed with brain metastases from lung cancer and underwent a craniotomy. Many fungal hyphae were found in the left parietal lesion, and the final pathological diagnosis of intracranial mucormycosis. After craniotomy and an entire course of treatment with liposomal amphotericin B, the patient was completely cured of both intracranial and pulmonary occupying lesions. We hope that this case experience will help expand neurosurgeons' differential diagnosis and treatment of such diseases. SN - 2405-8440 UR - https://www.unboundmedicine.com/medline/citation/36685477/Cerebral_mucormycosis_masquerading_as_brain_metastasis_from_lung_cancer:_A_case_report. DB - PRIME DP - Unbound Medicine ER -
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