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[Gastric secretion and acidity in elderly patients with duodenal peptic ulcer].
Vutr Boles. 1987; 26(4):46-9.VB

Abstract

46 patients over 60 years of age suffering from duodenal ulcer, 36 young patients with duodenal ulcer and 36 healthy aged persons (control group) have been examined after maximal pentagastrin stimulation. The results revealed that the aged patients with duodenal ulcer have significantly lower gastric secretion and acidity (BVO--87.7 +/- 36.8 ml/h, MVO--220.0 +/- 52.8 ml/h, BAO--4.23 +/- 2.63 mmol/h, MAO--25.43 +/- 8.39 mmol/h, PAO--30.34 +/- 12.09 mmol/h) than the young patients with duodenal ulcer (p less than 0.01-0.001). The volume of gastric secretion and the degree of acidity of the aged patients with duodenal ulcer are significantly above the reference value (BVO--71.6 +/- 19.5 ml/h, MVO--174.8 +/- 34.9 ml/h, BAO--1.84 +/- 0.96 mmol/h, MAO--16.58 +/- 4.02 mmol/h, PAO--20.73 +/- 3.08 mmol/l) of the control group of healthy aged persons (p less than 0.02-0.001). The suggestion is put forward that the differences in gastric secretion and acidity between the patients and the healthy persons above 60 years of age are one of the basic factors for development and/or persistence of the ulcerous process in old age.

Authors

Stanchev I
No affiliation info available
Pavlov K
No affiliation info available

MeSH

AdolescentAdultAgedDuodenal UlcerGastric Acidity DeterminationGastric MucosaHumansMiddle AgedPentagastrinReference Values

Pub Type(s)

Comparative Study
Journal Article

Language

bul

PubMed ID

3673033

Citation

Stanchev, I, and K Pavlov. "[Gastric Secretion and Acidity in Elderly Patients With Duodenal Peptic Ulcer]." Vutreshni Bolesti, vol. 26, no. 4, 1987, pp. 46-9.
Stanchev I, Pavlov K. [Gastric secretion and acidity in elderly patients with duodenal peptic ulcer]. Vutr Boles. 1987;26(4):46-9.
Stanchev, I., & Pavlov, K. (1987). [Gastric secretion and acidity in elderly patients with duodenal peptic ulcer]. Vutreshni Bolesti, 26(4), 46-9.
Stanchev I, Pavlov K. [Gastric Secretion and Acidity in Elderly Patients With Duodenal Peptic Ulcer]. Vutr Boles. 1987;26(4):46-9. PubMed PMID: 3673033.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Gastric secretion and acidity in elderly patients with duodenal peptic ulcer]. AU - Stanchev,I, AU - Pavlov,K, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 46 EP - 9 JF - Vutreshni bolesti JO - Vutr Boles VL - 26 IS - 4 N2 - 46 patients over 60 years of age suffering from duodenal ulcer, 36 young patients with duodenal ulcer and 36 healthy aged persons (control group) have been examined after maximal pentagastrin stimulation. The results revealed that the aged patients with duodenal ulcer have significantly lower gastric secretion and acidity (BVO--87.7 +/- 36.8 ml/h, MVO--220.0 +/- 52.8 ml/h, BAO--4.23 +/- 2.63 mmol/h, MAO--25.43 +/- 8.39 mmol/h, PAO--30.34 +/- 12.09 mmol/h) than the young patients with duodenal ulcer (p less than 0.01-0.001). The volume of gastric secretion and the degree of acidity of the aged patients with duodenal ulcer are significantly above the reference value (BVO--71.6 +/- 19.5 ml/h, MVO--174.8 +/- 34.9 ml/h, BAO--1.84 +/- 0.96 mmol/h, MAO--16.58 +/- 4.02 mmol/h, PAO--20.73 +/- 3.08 mmol/l) of the control group of healthy aged persons (p less than 0.02-0.001). The suggestion is put forward that the differences in gastric secretion and acidity between the patients and the healthy persons above 60 years of age are one of the basic factors for development and/or persistence of the ulcerous process in old age. SN - 0506-2772 UR - https://www.unboundmedicine.com/medline/citation/3673033/[Gastric_secretion_and_acidity_in_elderly_patients_with_duodenal_peptic_ulcer]_ DB - PRIME DP - Unbound Medicine ER -