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Monitoring of zinc protoporphyrin levels in blood following occupational lead exposure.
Am J Ind Med. 1987; 12(4):385-98.AJ

Abstract

The value of measurements of zinc protoporphyrin in blood (ZPP) in the surveillance of workers occupationally exposed to lead has been studied. From a group of referents, consisting of 1,088 men and 511 women, it has been established that the normal mean ZPP is in the region of 25 micrograms/100 ml, and only rarely do values exceed 45 micrograms/100 ml. The higher ZPP values are frequently associated with low blood hemoglobin concentrations and appear to be manifestations of an iron-deficiency anemia. Women have higher ZPP values than men; smoking has no influence. Measurements of ZPP and blood lead concentration (PbB) have been made every other month for 2.5 years on a group of around 200 men and 40 women exposed to lead in a storage battery factory. The mean ZPP of the group throughout the period was 70.9 micrograms/100 ml blood, and a linear relation between log ZPP and PbB in the PbB range of 10-80 micrograms/100 ml has been established. ZPP thresholds in the control of excessive occupational lead exposure, and the economic advantage of ZPP measurements over PbB, are discussed.

Authors+Show Affiliations

Institute of Hygiene, University of Lund, Sweden.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3674027

Citation

Wildt, K, et al. "Monitoring of Zinc Protoporphyrin Levels in Blood Following Occupational Lead Exposure." American Journal of Industrial Medicine, vol. 12, no. 4, 1987, pp. 385-98.
Wildt K, Berlin M, Isberg PE. Monitoring of zinc protoporphyrin levels in blood following occupational lead exposure. Am J Ind Med. 1987;12(4):385-98.
Wildt, K., Berlin, M., & Isberg, P. E. (1987). Monitoring of zinc protoporphyrin levels in blood following occupational lead exposure. American Journal of Industrial Medicine, 12(4), 385-98.
Wildt K, Berlin M, Isberg PE. Monitoring of Zinc Protoporphyrin Levels in Blood Following Occupational Lead Exposure. Am J Ind Med. 1987;12(4):385-98. PubMed PMID: 3674027.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Monitoring of zinc protoporphyrin levels in blood following occupational lead exposure. AU - Wildt,K, AU - Berlin,M, AU - Isberg,P E, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 385 EP - 98 JF - American journal of industrial medicine JO - Am J Ind Med VL - 12 IS - 4 N2 - The value of measurements of zinc protoporphyrin in blood (ZPP) in the surveillance of workers occupationally exposed to lead has been studied. From a group of referents, consisting of 1,088 men and 511 women, it has been established that the normal mean ZPP is in the region of 25 micrograms/100 ml, and only rarely do values exceed 45 micrograms/100 ml. The higher ZPP values are frequently associated with low blood hemoglobin concentrations and appear to be manifestations of an iron-deficiency anemia. Women have higher ZPP values than men; smoking has no influence. Measurements of ZPP and blood lead concentration (PbB) have been made every other month for 2.5 years on a group of around 200 men and 40 women exposed to lead in a storage battery factory. The mean ZPP of the group throughout the period was 70.9 micrograms/100 ml blood, and a linear relation between log ZPP and PbB in the PbB range of 10-80 micrograms/100 ml has been established. ZPP thresholds in the control of excessive occupational lead exposure, and the economic advantage of ZPP measurements over PbB, are discussed. SN - 0271-3586 UR - https://www.unboundmedicine.com/medline/citation/3674027/Monitoring_of_zinc_protoporphyrin_levels_in_blood_following_occupational_lead_exposure_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0271-3586&date=1987&volume=12&issue=4&spage=385 DB - PRIME DP - Unbound Medicine ER -