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Clinical and Epidemiology Characteristics of COVID-19 Cases Detected During Mass Screening Campaign from July to October 2020 in Bujumbura, Burundi.
East Afr Health Res J. 2022; 6(2):127-133.EA

Abstract

BACKGROUND

Coronavirus disease of 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2 Virus). It was reported for the first time in Wuhan city, Hubei province of China. The first cases of COVID-19 in Burundi were identified on 31st March 2020. Several signs and symptoms, including mainly; fever, dry cough, fatigue, myalgia, and dyspnea are the most prominent characteristics of the disease. The aim of this study was to provide description of the clinical and epidemiological characteristics of COVID-19 cases identified during the mass screening campaign conducted between July and October, 2020 in Burundi.

METHODS

We conducted a retrospective secondary analysis of data of clients to the mass screening campaign in Bujumbura city that was run between July and October 2020. Clients with complete data and tested for COVID-19 with Reverse Transcription Polymerase Chain Reaction (RT-PCR) were included in the study. Epi-Info 7.2.2.6 was used to perform descriptive and analytical statistics and Quantum Geographic Information System (QGIS) was used for cases mapping. Association between positive cases and independent variables such as sex, history of contact with confirmed COVID-19 case was measured using chi-square statistical test at a p-value of .05.

RESULTS

The study included 20,114 participants. 243 (1.2%) were tested positive for COVID-19. The mean age for confirmed cases was 33 (±15) years. The majority of cases (72.8%) were between 20 and 59 years of age and they were predominantly males (67.9%). 164 (67.5%) were symptomatic and cough was the most frequent symptom observed 109 (66.5%), followed by rhinorrhea 69 (42.1%). Fever was present in only 18 (11.0%) of symptomatic patients. Participants with a history of contact with a COVID-19 confirmed case (aOR=2.2; 95%CI [1.6-3.0]; p-value <.001), were more likely to be positive for COVID-19. Also, those who were coughing (aOR=1.47; 95%CI [1.06-2.05]; p-value=.023) and having sore throat (aOR=2.4; 95%CI [1.1-4.9]; p-value=.02) were more likely to test positive for COVID-19.

CONCLUSION

This study revealed that a significant proportion (32.5%) of COVID-19 patients were silent carriers of the virus. Data highlighted that high proportion of cases were among the active age group and contacts with confirmed cases, and noted high proportion of asymptomatic cases at diagnosis. Measures including routine testing of asymptomatic contacts could contribute to tackling corona virus in Burundi.

Authors+Show Affiliations

Ministry of Public Health and Fight against AIDS, National Public Health Institute, Bujumbura, Burundi. Ministry of Public Health and Fight against AIDS, National Public Health Emergency Operation Centre, Bujumbura, Burundi.Ministry of Public Health and Fight against AIDS, National Public Health Emergency Operation Centre, Bujumbura, Burundi.Ministry of Public Health and Fight against AIDS, National Public Health Institute, Bujumbura, Burundi. Ministry of Public Health and Fight against AIDS, National Public Health Emergency Operation Centre, Bujumbura, Burundi.Ministry of Public Health and Fight against AIDS, National Public Health Emergency Operation Centre, Bujumbura, Burundi.Ministry of Public Health and Fight against AIDS, National Public Health Emergency Operation Centre, Bujumbura, Burundi.World Health Organization, Country office, Bujumbura, Burundi.Ministry of Public Health and Fight against AIDS, National Public Health Institute, Bujumbura, Burundi.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

36751687

Citation

Nkunzimana, Edouard, et al. "Clinical and Epidemiology Characteristics of COVID-19 Cases Detected During Mass Screening Campaign From July to October 2020 in Bujumbura, Burundi." The East African Health Research Journal, vol. 6, no. 2, 2022, pp. 127-133.
Nkunzimana E, Bizimana JC, Ndoreraho A, et al. Clinical and Epidemiology Characteristics of COVID-19 Cases Detected During Mass Screening Campaign from July to October 2020 in Bujumbura, Burundi. East Afr Health Res J. 2022;6(2):127-133.
Nkunzimana, E., Bizimana, J. C., Ndoreraho, A., Iteka, L., Butoyi, P., Leopold, O., & Nyandwi, J. (2022). Clinical and Epidemiology Characteristics of COVID-19 Cases Detected During Mass Screening Campaign from July to October 2020 in Bujumbura, Burundi. The East African Health Research Journal, 6(2), 127-133. https://doi.org/10.24248/eahrj.v6i2.689
Nkunzimana E, et al. Clinical and Epidemiology Characteristics of COVID-19 Cases Detected During Mass Screening Campaign From July to October 2020 in Bujumbura, Burundi. East Afr Health Res J. 2022;6(2):127-133. PubMed PMID: 36751687.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and Epidemiology Characteristics of COVID-19 Cases Detected During Mass Screening Campaign from July to October 2020 in Bujumbura, Burundi. AU - Nkunzimana,Edouard, AU - Bizimana,Jean Claude, AU - Ndoreraho,Adolphe, AU - Iteka,Liesse, AU - Butoyi,Pascal, AU - Leopold,Ouedraogo, AU - Nyandwi,Joseph, Y1 - 2022/11/30/ PY - 2022/3/10/received PY - 2022/11/25/accepted PY - 2023/2/8/entrez PY - 2023/2/9/pubmed PY - 2023/2/9/medline SP - 127 EP - 133 JF - The East African health research journal JO - East Afr Health Res J VL - 6 IS - 2 N2 - BACKGROUND: Coronavirus disease of 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2 Virus). It was reported for the first time in Wuhan city, Hubei province of China. The first cases of COVID-19 in Burundi were identified on 31st March 2020. Several signs and symptoms, including mainly; fever, dry cough, fatigue, myalgia, and dyspnea are the most prominent characteristics of the disease. The aim of this study was to provide description of the clinical and epidemiological characteristics of COVID-19 cases identified during the mass screening campaign conducted between July and October, 2020 in Burundi. METHODS: We conducted a retrospective secondary analysis of data of clients to the mass screening campaign in Bujumbura city that was run between July and October 2020. Clients with complete data and tested for COVID-19 with Reverse Transcription Polymerase Chain Reaction (RT-PCR) were included in the study. Epi-Info 7.2.2.6 was used to perform descriptive and analytical statistics and Quantum Geographic Information System (QGIS) was used for cases mapping. Association between positive cases and independent variables such as sex, history of contact with confirmed COVID-19 case was measured using chi-square statistical test at a p-value of .05. RESULTS: The study included 20,114 participants. 243 (1.2%) were tested positive for COVID-19. The mean age for confirmed cases was 33 (±15) years. The majority of cases (72.8%) were between 20 and 59 years of age and they were predominantly males (67.9%). 164 (67.5%) were symptomatic and cough was the most frequent symptom observed 109 (66.5%), followed by rhinorrhea 69 (42.1%). Fever was present in only 18 (11.0%) of symptomatic patients. Participants with a history of contact with a COVID-19 confirmed case (aOR=2.2; 95%CI [1.6-3.0]; p-value <.001), were more likely to be positive for COVID-19. Also, those who were coughing (aOR=1.47; 95%CI [1.06-2.05]; p-value=.023) and having sore throat (aOR=2.4; 95%CI [1.1-4.9]; p-value=.02) were more likely to test positive for COVID-19. CONCLUSION: This study revealed that a significant proportion (32.5%) of COVID-19 patients were silent carriers of the virus. Data highlighted that high proportion of cases were among the active age group and contacts with confirmed cases, and noted high proportion of asymptomatic cases at diagnosis. Measures including routine testing of asymptomatic contacts could contribute to tackling corona virus in Burundi. SN - 2520-5285 UR - https://www.unboundmedicine.com/medline/citation/36751687/Clinical_and_Epidemiology_Characteristics_of_COVID-19_Cases_Detected_During_Mass_Screening_Campaign_from_July_to_October_2020_in_Bujumbura,_Burundi. DB - PRIME DP - Unbound Medicine ER -
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