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Time course of end-expired carbon monoxide concentration is important in studies of cigarette smoking.
Clin Sci (Lond). 1987 Nov; 73(5):553-5.CS

Abstract

1. Fifteen asymptomatic habitual smokers each smoked one of their usual cigarettes, not having smoked for 2 h. End-expired carbon monoxide concentration (EECO) was measured with an Ecolyzer 2000 series analyser before smoking (pre-S value), 1 min after finishing smoking (post-S value) and then at intervals up to 1 h. 2. The mean EECO boost (increase) over all subjects declined biphasically after smoking, with an initial fast phase from 1 to 5 min, and then a slow phase from 5 to 60 min. EECO fell by as much in the first 5 min as in the next hour. 3. Post-S EECO was related to pre-S EECO (r = 0.89, P less than 0.001), but EECO boost was not related to pre-S (r = 0.00). EECO boost was unaffected by the sampling manoeuvre. 4. EECO measurements in epidemiological and smoking studies should not be made for at least 5 min after a cigarette is finished.

Authors+Show Affiliations

Woodman G
Department of Thoracic Medicine, Royal Free Hospital, London.
Wintoniuk DM
No affiliation info available
Taylor RG
No affiliation info available
Clarke SW
No affiliation info available

MeSH

AdultBreath TestsCarbon MonoxideFemaleHumansMaleRespirationSmokingTime Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3677561

Citation

Woodman, G, et al. "Time Course of End-expired Carbon Monoxide Concentration Is Important in Studies of Cigarette Smoking." Clinical Science (London, England : 1979), vol. 73, no. 5, 1987, pp. 553-5.
Woodman G, Wintoniuk DM, Taylor RG, et al. Time course of end-expired carbon monoxide concentration is important in studies of cigarette smoking. Clin Sci (Lond). 1987;73(5):553-5.
Woodman, G., Wintoniuk, D. M., Taylor, R. G., & Clarke, S. W. (1987). Time course of end-expired carbon monoxide concentration is important in studies of cigarette smoking. Clinical Science (London, England : 1979), 73(5), 553-5.
Woodman G, et al. Time Course of End-expired Carbon Monoxide Concentration Is Important in Studies of Cigarette Smoking. Clin Sci (Lond). 1987;73(5):553-5. PubMed PMID: 3677561.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Time course of end-expired carbon monoxide concentration is important in studies of cigarette smoking. AU - Woodman,G, AU - Wintoniuk,D M, AU - Taylor,R G, AU - Clarke,S W, PY - 1987/11/1/pubmed PY - 1987/11/1/medline PY - 1987/11/1/entrez SP - 553 EP - 5 JF - Clinical science (London, England : 1979) JO - Clin Sci (Lond) VL - 73 IS - 5 N2 - 1. Fifteen asymptomatic habitual smokers each smoked one of their usual cigarettes, not having smoked for 2 h. End-expired carbon monoxide concentration (EECO) was measured with an Ecolyzer 2000 series analyser before smoking (pre-S value), 1 min after finishing smoking (post-S value) and then at intervals up to 1 h. 2. The mean EECO boost (increase) over all subjects declined biphasically after smoking, with an initial fast phase from 1 to 5 min, and then a slow phase from 5 to 60 min. EECO fell by as much in the first 5 min as in the next hour. 3. Post-S EECO was related to pre-S EECO (r = 0.89, P less than 0.001), but EECO boost was not related to pre-S (r = 0.00). EECO boost was unaffected by the sampling manoeuvre. 4. EECO measurements in epidemiological and smoking studies should not be made for at least 5 min after a cigarette is finished. SN - 0143-5221 UR - https://www.unboundmedicine.com/medline/citation/3677561/Time_course_of_end_expired_carbon_monoxide_concentration_is_important_in_studies_of_cigarette_smoking_ DB - PRIME DP - Unbound Medicine ER -