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Effects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials.
Curr Nutr Rep. 2023 03; 12(1):167-180.CN

Abstract

PURPOSE OF REVIEW

The current systematic review and meta-analysis was done to evaluate the effects of selenium and probiotic co-supplementation on lipid profile and glycemia indices of the adult population using randomized controlled clinical trials (RCTs).

RECENT FINDINGS

Five studies involving 282 participants with a sample size ranging from 38 to 79 were eligible to be enrolled in the current study. Co-supplementation with probiotic and selenium reduced fasting plasma glucose (WMD = -4.02 mg/dL; 95% CI: -5.87 to -2.18; P < 0.001), insulin (WMD = -2.50 mIU/mL; 95% CI: -3.11 to -1.90; P < 0.001), homeostatic model assessment for insulin resistance (WMD = -0.59; 95% CI: -0.74 to -0.43; P < 0.001), quantitative insulin sensitivity check index (WMD = 0.01; 95% CI: 0.01 to 0.02; P < 0.001), total cholesterol (WMD = -12.75 mg/dL; 95% CI: -19.44 to -6.07; P < 0.001), low-density lipoprotein cholesterol (WMD = -7.09 mg/dL; 95% CI: -13.45 to -0.73; P = 0.029), and triglyceride (WMD = -14.38 mg/dL; 95% CI: -23.13 to -5.62; P = 0.001). The findings of the current systematic review and meta-analysis suggested that co-supplementation with probiotics and selenium may benefit adults in terms of glycemia indices and lipid profile. However, due to the small number of included studies, further trials are needed to confirm our findings.

Links

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Authors+Show Affiliations

Mohammadparast V
School of Health Sciences, Massey University, PO Box 756, Wellington, 6021, New Zealand.
Mohammadi T
Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Karimi E
Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Mallard BL
School of Health Sciences, Massey University, PO Box 756, Wellington, 6021, New Zealand. B.Mallard@massey.ac.nz.

MeSH

AdultHumansCholesterolDietary SupplementsProbioticsRandomized Controlled Trials as TopicSeleniumTriglyceridesLipid Metabolism

Pub Type(s)

Meta-Analysis
Systematic Review
Journal Article
Review
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

36781602

Citation

Mohammadparast, Vida, et al. "Effects of Probiotic and Selenium Co-supplementation On Lipid Profile and Glycemia Indices: a Systematic Review and Meta-analysis of Randomized Clinical Trials." Current Nutrition Reports, vol. 12, no. 1, 2023, pp. 167-180.
Mohammadparast V, Mohammadi T, Karimi E, et al. Effects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Curr Nutr Rep. 2023;12(1):167-180.
Mohammadparast, V., Mohammadi, T., Karimi, E., & Mallard, B. L. (2023). Effects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Current Nutrition Reports, 12(1), 167-180. https://doi.org/10.1007/s13668-023-00448-1
Mohammadparast V, et al. Effects of Probiotic and Selenium Co-supplementation On Lipid Profile and Glycemia Indices: a Systematic Review and Meta-analysis of Randomized Clinical Trials. Curr Nutr Rep. 2023;12(1):167-180. PubMed PMID: 36781602.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials. AU - Mohammadparast,Vida, AU - Mohammadi,Tanin, AU - Karimi,Elham, AU - Mallard,Beth L, Y1 - 2023/02/13/ PY - 2022/10/18/accepted PY - 2023/2/14/pubmed PY - 2023/3/3/medline PY - 2023/2/13/entrez KW - Glycemia indices KW - Lipid profile KW - Probiotics KW - Selenium SP - 167 EP - 180 JF - Current nutrition reports JO - Curr Nutr Rep VL - 12 IS - 1 N2 - PURPOSE OF REVIEW: The current systematic review and meta-analysis was done to evaluate the effects of selenium and probiotic co-supplementation on lipid profile and glycemia indices of the adult population using randomized controlled clinical trials (RCTs). RECENT FINDINGS: Five studies involving 282 participants with a sample size ranging from 38 to 79 were eligible to be enrolled in the current study. Co-supplementation with probiotic and selenium reduced fasting plasma glucose (WMD = -4.02 mg/dL; 95% CI: -5.87 to -2.18; P < 0.001), insulin (WMD = -2.50 mIU/mL; 95% CI: -3.11 to -1.90; P < 0.001), homeostatic model assessment for insulin resistance (WMD = -0.59; 95% CI: -0.74 to -0.43; P < 0.001), quantitative insulin sensitivity check index (WMD = 0.01; 95% CI: 0.01 to 0.02; P < 0.001), total cholesterol (WMD = -12.75 mg/dL; 95% CI: -19.44 to -6.07; P < 0.001), low-density lipoprotein cholesterol (WMD = -7.09 mg/dL; 95% CI: -13.45 to -0.73; P = 0.029), and triglyceride (WMD = -14.38 mg/dL; 95% CI: -23.13 to -5.62; P = 0.001). The findings of the current systematic review and meta-analysis suggested that co-supplementation with probiotics and selenium may benefit adults in terms of glycemia indices and lipid profile. However, due to the small number of included studies, further trials are needed to confirm our findings. SN - 2161-3311 UR - https://www.unboundmedicine.com/medline/citation/36781602/Effects_of_Probiotic_and_Selenium_Co_supplementation_on_Lipid_Profile_and_Glycemia_Indices:_A_Systematic_Review_and_Meta_analysis_of_Randomized_Clinical_Trials_ DB - PRIME DP - Unbound Medicine ER -
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