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Dandy-Walker syndrome revisited.
Pediatr Neurosci. 1987; 13(1):45-51.PN

Abstract

The Dandy-Walker syndrome is said to be associated with a high incidence of mental retardation and motor dysfunction leading some to suggest termination of the affected fetus in utero. Since this view seemed contrary to our experience, we reviewed 19 patients with the Dandy-Walker syndrome diagnosed from 1966 to 1983. Thirteen patients with Dandy-Walker syndrome were diagnosed before 6 months of age and followed for more than 2 years (mean: 10 years). In the absence of other associated major abnormalities, 7 of 8 (88%) are functioning well and have attended regular schools. Two of these seven have had special help with isolated learning problems. None of these patients have significant motor disability. One additional patient with normal intellectual and motor function died of acute shunt malfunction. In the remaining 4 patients with Dandy-Walker-associated abnormalities, 3 (75%) have severe intellectual retardation and spastic cerebral palsy. Five of six patients (83%) with Dandy-Walker syndrome diagnosed after 6 months of age are normal. The outcome of patients with Dandy-Walker syndrome appears far better than previously reported.

Authors+Show Affiliations

Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Md.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3684815

Citation

Maria, B L., et al. "Dandy-Walker Syndrome Revisited." Pediatric Neuroscience, vol. 13, no. 1, 1987, pp. 45-51.
Maria BL, Zinreich SJ, Carson BC, et al. Dandy-Walker syndrome revisited. Pediatr Neurosci. 1987;13(1):45-51.
Maria, B. L., Zinreich, S. J., Carson, B. C., Rosenbaum, A. E., & Freeman, J. M. (1987). Dandy-Walker syndrome revisited. Pediatric Neuroscience, 13(1), 45-51.
Maria BL, et al. Dandy-Walker Syndrome Revisited. Pediatr Neurosci. 1987;13(1):45-51. PubMed PMID: 3684815.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dandy-Walker syndrome revisited. AU - Maria,B L, AU - Zinreich,S J, AU - Carson,B C, AU - Rosenbaum,A E, AU - Freeman,J M, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 45 EP - 51 JF - Pediatric neuroscience JO - Pediatr Neurosci VL - 13 IS - 1 N2 - The Dandy-Walker syndrome is said to be associated with a high incidence of mental retardation and motor dysfunction leading some to suggest termination of the affected fetus in utero. Since this view seemed contrary to our experience, we reviewed 19 patients with the Dandy-Walker syndrome diagnosed from 1966 to 1983. Thirteen patients with Dandy-Walker syndrome were diagnosed before 6 months of age and followed for more than 2 years (mean: 10 years). In the absence of other associated major abnormalities, 7 of 8 (88%) are functioning well and have attended regular schools. Two of these seven have had special help with isolated learning problems. None of these patients have significant motor disability. One additional patient with normal intellectual and motor function died of acute shunt malfunction. In the remaining 4 patients with Dandy-Walker-associated abnormalities, 3 (75%) have severe intellectual retardation and spastic cerebral palsy. Five of six patients (83%) with Dandy-Walker syndrome diagnosed after 6 months of age are normal. The outcome of patients with Dandy-Walker syndrome appears far better than previously reported. SN - 0255-7975 UR - https://www.unboundmedicine.com/medline/citation/3684815/Dandy_Walker_syndrome_revisited_ L2 - https://www.diseaseinfosearch.org/result/2112 DB - PRIME DP - Unbound Medicine ER -