Tags

Type your tag names separated by a space and hit enter

Oxidation of Pharmaceuticals by Ferrate(VI)-Amino Acid Systems: Enhancement by Proline.
J Phys Chem A. 2023 Mar 16; 127(10):2314-2321.JP

Abstract

The occurrence of micropollutants in water threatens public health and ecology. Removal of micropollutants such as pharmaceuticals by a green oxidant, ferrate(VI) (FeVIO42-, Fe(VI)) can be accomplished. However, electron-deficient pharmaceuticals, such as carbamazepine (CBZ) showed a low removal rate by Fe(VI). This work investigates the activation of Fe(VI) by adding nine amino acids (AA) of different functionalities to accelerate the removal of CBZ in water under mild alkaline conditions. Among the studied amino acids, proline, a cyclic AA, had the highest removal of CBZ. The accelerated effect of proline was ascribed by demonstrating the involvement of highly reactive intermediate Fe(V) species, generated by one-electron transfer by the reaction of Fe(VI) with proline (i.e., Fe(VI) + proline → Fe(V) + proline•). The degradation kinetics of CBZ by a Fe(VI)-proline system was interpreted by kinetic modeling of the reactions involved that estimated the rate of the reaction of Fe(V) with CBZ as (1.03 ± 0.21) × 106 M-1 s-1, which was several orders of magnitude greater than that of Fe(VI) of 2.25 M-1 s-1. Overall, natural compounds such as amino acids may be applied to increase the removal efficiency of recalcitrant micropollutants by Fe(VI).

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Sharma VK
Department of Environmental and Occupational Health, School of Public Health, Texas A&M University, College Station, Texas 77843-8371, United States.
Wang J
School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Feng M
Department of Environmental and Occupational Health, School of Public Health, Texas A&M University, College Station, Texas 77843-8371, United States.
Huang CH
School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.

MeSH

Amino AcidsProlineWater Pollutants, ChemicalOxidation-ReductionKineticsPharmaceutical Preparations

Pub Type(s)

Journal Article

Language

eng

PubMed ID

36862970

Citation

Sharma, Virender K., et al. "Oxidation of Pharmaceuticals By Ferrate(VI)-Amino Acid Systems: Enhancement By Proline." The Journal of Physical Chemistry. A, vol. 127, no. 10, 2023, pp. 2314-2321.
Sharma VK, Wang J, Feng M, et al. Oxidation of Pharmaceuticals by Ferrate(VI)-Amino Acid Systems: Enhancement by Proline. J Phys Chem A. 2023;127(10):2314-2321.
Sharma, V. K., Wang, J., Feng, M., & Huang, C. H. (2023). Oxidation of Pharmaceuticals by Ferrate(VI)-Amino Acid Systems: Enhancement by Proline. The Journal of Physical Chemistry. A, 127(10), 2314-2321. https://doi.org/10.1021/acs.jpca.3c00134
Sharma VK, et al. Oxidation of Pharmaceuticals By Ferrate(VI)-Amino Acid Systems: Enhancement By Proline. J Phys Chem A. 2023 Mar 16;127(10):2314-2321. PubMed PMID: 36862970.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oxidation of Pharmaceuticals by Ferrate(VI)-Amino Acid Systems: Enhancement by Proline. AU - Sharma,Virender K, AU - Wang,Junyue, AU - Feng,Mingbao, AU - Huang,Ching-Hua, Y1 - 2023/03/02/ PY - 2023/3/3/pubmed PY - 2023/3/3/medline PY - 2023/3/2/entrez SP - 2314 EP - 2321 JF - The journal of physical chemistry. A JO - J Phys Chem A VL - 127 IS - 10 N2 - The occurrence of micropollutants in water threatens public health and ecology. Removal of micropollutants such as pharmaceuticals by a green oxidant, ferrate(VI) (FeVIO42-, Fe(VI)) can be accomplished. However, electron-deficient pharmaceuticals, such as carbamazepine (CBZ) showed a low removal rate by Fe(VI). This work investigates the activation of Fe(VI) by adding nine amino acids (AA) of different functionalities to accelerate the removal of CBZ in water under mild alkaline conditions. Among the studied amino acids, proline, a cyclic AA, had the highest removal of CBZ. The accelerated effect of proline was ascribed by demonstrating the involvement of highly reactive intermediate Fe(V) species, generated by one-electron transfer by the reaction of Fe(VI) with proline (i.e., Fe(VI) + proline → Fe(V) + proline•). The degradation kinetics of CBZ by a Fe(VI)-proline system was interpreted by kinetic modeling of the reactions involved that estimated the rate of the reaction of Fe(V) with CBZ as (1.03 ± 0.21) × 106 M-1 s-1, which was several orders of magnitude greater than that of Fe(VI) of 2.25 M-1 s-1. Overall, natural compounds such as amino acids may be applied to increase the removal efficiency of recalcitrant micropollutants by Fe(VI). SN - 1520-5215 UR - https://www.unboundmedicine.com/medline/citation/36862970/Oxidation_of_Pharmaceuticals_by_Ferrate_VI__Amino_Acid_Systems:_Enhancement_by_Proline_ DB - PRIME DP - Unbound Medicine ER -