Rh(III)-catalyzed (5 + 2)-cycloaddition reactions of ortho-hydroxyethyl phenols with internal alkynes: efficient synthesis of benzoxepines.
Org Biomol Chem. 2023 Mar 22; 21(12):2516-2523.OB

Abstract

An unprecedented (5 + 2)-cycloaddition reaction of ortho-hydroxyethyl phenol and internal alkyne was developed. This Rh(III)-catalyzed reaction provided benzoxepine derivatives which have very high biological significance. A wide range of ortho-hydroxyethyl phenols and internal alkynes were studied to provide the benzoxepines in high yields.

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Authors+Show Affiliations

Bhorali P

Applied Organic Chemistry, Chemical Sciences & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat 785006, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India. skgogoi1@gmail.com.

Phukon J

Gogoi S

Pub Type(s)

Journal Article

Language

eng

PubMed ID

36891904

Citation

Bhorali, Pratiksha, et al. "Rh(III)-catalyzed (5 + 2)-cycloaddition Reactions of Ortho-hydroxyethyl Phenols With Internal Alkynes: Efficient Synthesis of Benzoxepines." Organic & Biomolecular Chemistry, vol. 21, no. 12, 2023, pp. 2516-2523.

Bhorali P, Phukon J, Gogoi S. Rh(III)-catalyzed (5 + 2)-cycloaddition reactions of ortho-hydroxyethyl phenols with internal alkynes: efficient synthesis of benzoxepines. Org Biomol Chem. 2023;21(12):2516-2523.

Bhorali, P., Phukon, J., & Gogoi, S. (2023). Rh(III)-catalyzed (5 + 2)-cycloaddition reactions of ortho-hydroxyethyl phenols with internal alkynes: efficient synthesis of benzoxepines. Organic & Biomolecular Chemistry, 21(12), 2516-2523. https://doi.org/10.1039/d3ob00170a

Bhorali P, Phukon J, Gogoi S. Rh(III)-catalyzed (5 + 2)-cycloaddition Reactions of Ortho-hydroxyethyl Phenols With Internal Alkynes: Efficient Synthesis of Benzoxepines. Org Biomol Chem. 2023 Mar 22;21(12):2516-2523. PubMed PMID: 36891904.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Rh(III)-catalyzed (5 + 2)-cycloaddition reactions of ortho-hydroxyethyl phenols with internal alkynes: efficient synthesis of benzoxepines. AU - Bhorali,Pratiksha, AU - Phukon,Jyotshna, AU - Gogoi,Sanjib, Y1 - 2023/03/22/ PY - 2023/3/10/pubmed PY - 2023/3/10/medline PY - 2023/3/9/entrez SP - 2516 EP - 2523 JF - Organic & biomolecular chemistry JO - Org Biomol Chem VL - 21 IS - 12 N2 - An unprecedented (5 + 2)-cycloaddition reaction of ortho-hydroxyethyl phenol and internal alkyne was developed. This Rh(III)-catalyzed reaction provided benzoxepine derivatives which have very high biological significance. A wide range of ortho-hydroxyethyl phenols and internal alkynes were studied to provide the benzoxepines in high yields. SN - 1477-0539 UR - https://www.unboundmedicine.com/medline/citation/36891904/Rh_III__catalyzed__5_+_2__cycloaddition_reactions_of_ortho_hydroxyethyl_phenols_with_internal_alkynes:_efficient_synthesis_of_benzoxepines_ DB - PRIME DP - Unbound Medicine ER -

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Rh(III)-catalyzed (5 + 2)-cycloaddition reactions of ortho-hydroxyethyl phenols with internal alkynes: efficient synthesis of benzoxepines.Org Biomol Chem. 2023 Mar 22; 21(12):2516-2523.OB