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Response to "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany".
Arthritis Res Ther. 2023 03 14; 25(1):41.AR

Abstract

We have read the article entitled "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany" by Heiligenhaus et al. While we appreciate the work conducted by the authors, we have several comments we would like to address. First, the follow-up interval of 2 years is too short to conclude that the clinical course between two chronic pathologies is not significantly different. Second, remission status was determined by uveitis inactivity during the 2-year follow-up visit without any mention of flare frequency or length of remission, which is not a reliable measure of uveitis control. Third, ANA-positive idiopathic anterior uveitis is not a classification with a distinct clinical phenotype, and additional reports of serologic investigations would have been helpful.

Authors+Show Affiliations

The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA. Massachusetts Eye Research and Surgery Institution, 1440 Main St. Ste. 201, Waltham, MA, 02451, USA.The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA. Massachusetts Eye Research and Surgery Institution, 1440 Main St. Ste. 201, Waltham, MA, 02451, USA.The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA. Massachusetts Eye Research and Surgery Institution, 1440 Main St. Ste. 201, Waltham, MA, 02451, USA.The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA. Massachusetts Eye Research and Surgery Institution, 1440 Main St. Ste. 201, Waltham, MA, 02451, USA.The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA. sfoster@mersi.com. Massachusetts Eye Research and Surgery Institution, 1440 Main St. Ste. 201, Waltham, MA, 02451, USA. sfoster@mersi.com. Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. sfoster@mersi.com.

Pub Type(s)

Letter
Comment

Language

eng

PubMed ID

36918966

Citation

Zhou, Avery, et al. "Response to "Similarities in Clinical Course and Outcome Between Juvenile Idiopathic Arthritis (JIA)-associated and ANA-positive Idiopathic Anterior Uveitis: Data From a Population-based Nationwide Study in Germany"." Arthritis Research & Therapy, vol. 25, no. 1, 2023, p. 41.
Zhou A, Babiker F, Philip AM, et al. Response to "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany". Arthritis Res Ther. 2023;25(1):41.
Zhou, A., Babiker, F., Philip, A. M., Anesi, S. D., & Foster, C. S. (2023). Response to "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany". Arthritis Research & Therapy, 25(1), 41. https://doi.org/10.1186/s13075-023-03021-x
Zhou A, et al. Response to "Similarities in Clinical Course and Outcome Between Juvenile Idiopathic Arthritis (JIA)-associated and ANA-positive Idiopathic Anterior Uveitis: Data From a Population-based Nationwide Study in Germany". Arthritis Res Ther. 2023 03 14;25(1):41. PubMed PMID: 36918966.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Response to "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany". AU - Zhou,Avery, AU - Babiker,Fatima, AU - Philip,Andrew M, AU - Anesi,Stephen D, AU - Foster,C Stephen, Y1 - 2023/03/14/ PY - 2022/10/04/received PY - 2023/02/27/accepted PY - 2023/3/15/entrez PY - 2023/3/16/pubmed PY - 2023/3/17/medline SP - 41 EP - 41 JF - Arthritis research & therapy JO - Arthritis Res Ther VL - 25 IS - 1 N2 - We have read the article entitled "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany" by Heiligenhaus et al. While we appreciate the work conducted by the authors, we have several comments we would like to address. First, the follow-up interval of 2 years is too short to conclude that the clinical course between two chronic pathologies is not significantly different. Second, remission status was determined by uveitis inactivity during the 2-year follow-up visit without any mention of flare frequency or length of remission, which is not a reliable measure of uveitis control. Third, ANA-positive idiopathic anterior uveitis is not a classification with a distinct clinical phenotype, and additional reports of serologic investigations would have been helpful. SN - 1478-6362 UR - https://www.unboundmedicine.com/medline/citation/36918966/Response_to_"Similarities_in_clinical_course_and_outcome_between_juvenile_idiopathic_arthritis__JIA__associated_and_ANA_positive_idiopathic_anterior_uveitis:_data_from_a_population_based_nationwide_study_in_Germany"_ DB - PRIME DP - Unbound Medicine ER -