Tags

Type your tag names separated by a space and hit enter

Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals.

Abstract

The effect of ascorbic acid on the absorption of non-heme iron was studied in 299 subjects. Different meals in which the non-heme iron was labelled with two different radio-iron isotopes were served with and without ascorbic acid to the same subject. Other meals containing foods with a known high content of ascorbic acid were also studied. Studies were also made giving different amounts of ascorbic acid with different meals. Marked differences in the enhancement of iron absorption were seen when ascorbic acid was given in different meals. It is suggested that ascorbic acid promotes iron absorption from the diet by reducing the negative effect on iron absorption of certain ligands such as phytates and tannins present in the diet. This interpretation is supported by observations that the most pronounced effects of ascorbic acid were found in meals with a high content of ligands known to inhibit iron absorption. Crystalline ascorbic acid and native ascorbic acid in foods appeared to have the same effect in promoting absorption of iron. The results indicate that ascorbic acid has a key physiologic role in facilitating the absorption of non-heme iron from the diet and that about 50 mg of the vitamin in each main meal is desirable for optimum effect.

Authors

, ,

Source

Human nutrition. Applied nutrition 40:2 1986 Apr pg 97-113

MeSH

Adult
Ascorbic Acid
Dose-Response Relationship, Drug
Female
Food
Food Analysis
Humans
Intestinal Absorption
Iron
Male
Middle Aged

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3700141

Citation

Hallberg, L, et al. "Effect of Ascorbic Acid On Iron Absorption From Different Types of Meals. Studies With Ascorbic-acid-rich Foods and Synthetic Ascorbic Acid Given in Different Amounts With Different Meals." Human Nutrition. Applied Nutrition, vol. 40, no. 2, 1986, pp. 97-113.
Hallberg L, Brune M, Rossander L. Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals. Hum Nutr Appl Nutr. 1986;40(2):97-113.
Hallberg, L., Brune, M., & Rossander, L. (1986). Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals. Human Nutrition. Applied Nutrition, 40(2), pp. 97-113.
Hallberg L, Brune M, Rossander L. Effect of Ascorbic Acid On Iron Absorption From Different Types of Meals. Studies With Ascorbic-acid-rich Foods and Synthetic Ascorbic Acid Given in Different Amounts With Different Meals. Hum Nutr Appl Nutr. 1986;40(2):97-113. PubMed PMID: 3700141.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals. AU - Hallberg,L, AU - Brune,M, AU - Rossander,L, PY - 1986/4/1/pubmed PY - 1986/4/1/medline PY - 1986/4/1/entrez SP - 97 EP - 113 JF - Human nutrition. Applied nutrition JO - Hum Nutr Appl Nutr VL - 40 IS - 2 N2 - The effect of ascorbic acid on the absorption of non-heme iron was studied in 299 subjects. Different meals in which the non-heme iron was labelled with two different radio-iron isotopes were served with and without ascorbic acid to the same subject. Other meals containing foods with a known high content of ascorbic acid were also studied. Studies were also made giving different amounts of ascorbic acid with different meals. Marked differences in the enhancement of iron absorption were seen when ascorbic acid was given in different meals. It is suggested that ascorbic acid promotes iron absorption from the diet by reducing the negative effect on iron absorption of certain ligands such as phytates and tannins present in the diet. This interpretation is supported by observations that the most pronounced effects of ascorbic acid were found in meals with a high content of ligands known to inhibit iron absorption. Crystalline ascorbic acid and native ascorbic acid in foods appeared to have the same effect in promoting absorption of iron. The results indicate that ascorbic acid has a key physiologic role in facilitating the absorption of non-heme iron from the diet and that about 50 mg of the vitamin in each main meal is desirable for optimum effect. SN - 0263-8495 UR - https://www.unboundmedicine.com/medline/citation/3700141/Effect_of_ascorbic_acid_on_iron_absorption_from_different_types_of_meals__Studies_with_ascorbic_acid_rich_foods_and_synthetic_ascorbic_acid_given_in_different_amounts_with_different_meals_ L2 - https://medlineplus.gov/vitaminc.html DB - PRIME DP - Unbound Medicine ER -