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Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom.
Toxicon. 1986; 24(2):201-3.T

Abstract

Wyeth's polyvalent (Crotalidae) antivenom was tested in mice for its ability to neutralize local myonecrosis induced by crude Crotalus atrox venom. A light microscopic assay was used to quantitate myonecrosis after i.m. injection of antivenom-venom mixtures. The results indicate that antivenom neutralizes the local myotoxicity of up to 15 micrograms venom per g body weight of mice. This neutralization is significantly better than that previously reported for Crotalus viridis viridis venom.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3705097

Citation

Ownby, C L., and T R. Colberg. "Ability of Polyvalent (Crotalidae) Antivenom to Neutralize Local Myonecrosis Induced By Crotalus Atrox Venom." Toxicon : Official Journal of the International Society On Toxinology, vol. 24, no. 2, 1986, pp. 201-3.
Ownby CL, Colberg TR. Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom. Toxicon. 1986;24(2):201-3.
Ownby, C. L., & Colberg, T. R. (1986). Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom. Toxicon : Official Journal of the International Society On Toxinology, 24(2), 201-3.
Ownby CL, Colberg TR. Ability of Polyvalent (Crotalidae) Antivenom to Neutralize Local Myonecrosis Induced By Crotalus Atrox Venom. Toxicon. 1986;24(2):201-3. PubMed PMID: 3705097.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom. AU - Ownby,C L, AU - Colberg,T R, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 201 EP - 3 JF - Toxicon : official journal of the International Society on Toxinology JO - Toxicon VL - 24 IS - 2 N2 - Wyeth's polyvalent (Crotalidae) antivenom was tested in mice for its ability to neutralize local myonecrosis induced by crude Crotalus atrox venom. A light microscopic assay was used to quantitate myonecrosis after i.m. injection of antivenom-venom mixtures. The results indicate that antivenom neutralizes the local myotoxicity of up to 15 micrograms venom per g body weight of mice. This neutralization is significantly better than that previously reported for Crotalus viridis viridis venom. SN - 0041-0101 UR - https://www.unboundmedicine.com/medline/citation/3705097/Ability_of_polyvalent__Crotalidae__antivenom_to_neutralize_local_myonecrosis_induced_by_Crotalus_atrox_venom_ DB - PRIME DP - Unbound Medicine ER -