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Comparative Study of Cerebral Venous Thrombosis-risk factors, clinical course and outcome in Subjects with and without Covid-19 infection.
Cerebrovasc Dis Extra. 2023 Apr 25; 13(1):63-8.CD

Abstract

Background/ Objective: Cerebral venous thrombosis (CVT) has been increasingly reported in patients with COVID-19. Most published literature is descriptive and focuses only on CVT in COVID-19 patients. The objective of our study is to compare CVT patients' characteristics with and without an associated COVID-19 infection.

MATERIALS AND METHODS

This is a retrospective cross-sectional study. All adult patients with a confirmed diagnosis of CVT admitted to our hospital over a period of 30 months, from January 2019 to June 2021, were included. They were further divided into two groups, with and without COVID-19 infection.

RESULTS

A total of 115 CVT patients were included, 93 in non-COVID CVT and 22 in COVID CVT group. COVID-CVT patients were male predominant and of older age, with longer hospital stay, and higher inpatient mortality. COVID CVT patients presented with a higher frequency of headache (82% vs. 63%), seizures (64% vs. 37%, p=0.03), hemiparesis (41% vs. 24%), and visual changes (36% vs. 19%) as compared to non-COVID CVT patients. Venogram showed a higher frequency of superior sagittal sinus (64% vs. 42%) and internal jugular vein (23% vs. 12%) involvement in the COVID CVT cohort. More than 90% of patients in both groups received therapeutic anticoagulation. Mortality rates were higher in COVID CVT group (18% vs. 11%).

CONCLUSION

COVID-CVT patients were male predominant and of older age, with higher hospital stay, and higher inpatient mortality as compared to non-covid CVT patients.

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Authors

Hameed S
No affiliation info available
Hamza A
No affiliation info available
Taimuri B
No affiliation info available
Khan M
No affiliation info available
Mehndiratta MM
No affiliation info available
Wasay M
No affiliation info available

Pub Type(s)

News

Language

eng

PubMed ID

37166317

Citation

Hameed, Sajid, et al. "Comparative Study of Cerebral Venous Thrombosis-risk Factors, Clinical Course and Outcome in Subjects With and Without Covid-19 Infection." Cerebrovascular Diseases Extra, vol. 13, no. 1, 2023, pp. 63-8.
Hameed S, Hamza A, Taimuri B, et al. Comparative Study of Cerebral Venous Thrombosis-risk factors, clinical course and outcome in Subjects with and without Covid-19 infection. Cerebrovasc Dis Extra. 2023;13(1):63-8.
Hameed, S., Hamza, A., Taimuri, B., Khan, M., Mehndiratta, M. M., & Wasay, M. (2023). Comparative Study of Cerebral Venous Thrombosis-risk factors, clinical course and outcome in Subjects with and without Covid-19 infection. Cerebrovascular Diseases Extra, 13(1), 63-8. https://doi.org/10.1159/000530819
Hameed S, et al. Comparative Study of Cerebral Venous Thrombosis-risk Factors, Clinical Course and Outcome in Subjects With and Without Covid-19 Infection. Cerebrovasc Dis Extra. 2023 Apr 25;13(1):63-8. PubMed PMID: 37166317.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative Study of Cerebral Venous Thrombosis-risk factors, clinical course and outcome in Subjects with and without Covid-19 infection. AU - Hameed,Sajid, AU - Hamza,Anwar, AU - Taimuri,Bushra, AU - Khan,Maria, AU - Mehndiratta,Man Mohan, AU - Wasay,Mohammad, Y1 - 2023/04/25/ PY - 2023/3/1/received PY - 2023/4/18/accepted PY - 2023/5/11/medline PY - 2023/5/11/pubmed PY - 2023/5/11/entrez SP - 63 EP - 8 JF - Cerebrovascular diseases extra JO - Cerebrovasc Dis Extra VL - 13 IS - 1 N2 - UNLABELLED: Background/ Objective: Cerebral venous thrombosis (CVT) has been increasingly reported in patients with COVID-19. Most published literature is descriptive and focuses only on CVT in COVID-19 patients. The objective of our study is to compare CVT patients' characteristics with and without an associated COVID-19 infection. MATERIALS AND METHODS: This is a retrospective cross-sectional study. All adult patients with a confirmed diagnosis of CVT admitted to our hospital over a period of 30 months, from January 2019 to June 2021, were included. They were further divided into two groups, with and without COVID-19 infection. RESULTS: A total of 115 CVT patients were included, 93 in non-COVID CVT and 22 in COVID CVT group. COVID-CVT patients were male predominant and of older age, with longer hospital stay, and higher inpatient mortality. COVID CVT patients presented with a higher frequency of headache (82% vs. 63%), seizures (64% vs. 37%, p=0.03), hemiparesis (41% vs. 24%), and visual changes (36% vs. 19%) as compared to non-COVID CVT patients. Venogram showed a higher frequency of superior sagittal sinus (64% vs. 42%) and internal jugular vein (23% vs. 12%) involvement in the COVID CVT cohort. More than 90% of patients in both groups received therapeutic anticoagulation. Mortality rates were higher in COVID CVT group (18% vs. 11%). CONCLUSION: COVID-CVT patients were male predominant and of older age, with higher hospital stay, and higher inpatient mortality as compared to non-covid CVT patients. SN - 1664-5456 UR - https://www.unboundmedicine.com/medline/citation/37166317/Comparative_Study_of_Cerebral_Venous_Thrombosis-risk_factors,_clinical_course_and_outcome_in_Subjects_with_and_without_Covid-19_infection. DB - PRIME DP - Unbound Medicine ER -