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Immunosuppressive treatment for autoimmune blistering diseases does not impair production of neutralizing antibodies after "booster" dose of COVID-19 vaccine.
Int J Dermatol. 2023 Jul; 62(7):847-849.IJ

Abstract

Since vaccines against COVID-19 are available, it has been debated if immunosuppressed patients with autoimmune blistering diseases (AIBDs) should be advised to interrupt the immunosuppressive therapy before receiving the vaccine, with consequent risk to experience a flare of disease. In the present study, we measured the neutralizing antibodies production after anti-SARS-CoV-2 vaccination in patients with AIBDs on immunosuppressive treatment, compared to healthy controls. Our results give strength to the hypothesis that these patients do not need to discontinue their therapy to produce effective levels of neutralizing antibodies, in other words to achieve successful protection.

Authors+Show Affiliations

DISSAL - Section of Dermatology, University of Genoa, Genoa, Italy. San Martino IRCCS Polyclinic Hospital, Genoa, Italy.DISSAL - Section of Dermatology, University of Genoa, Genoa, Italy. San Martino IRCCS Polyclinic Hospital, Genoa, Italy.DISSAL - Section of Dermatology, University of Genoa, Genoa, Italy. San Martino IRCCS Polyclinic Hospital, Genoa, Italy.DISSAL - Section of Dermatology, University of Genoa, Genoa, Italy. San Martino IRCCS Polyclinic Hospital, Genoa, Italy.DISSAL - Section of Dermatology, University of Genoa, Genoa, Italy. San Martino IRCCS Polyclinic Hospital, Genoa, Italy.DISSAL - Section of Dermatology, University of Genoa, Genoa, Italy. San Martino IRCCS Polyclinic Hospital, Genoa, Italy.

Pub Type(s)

News

Language

eng

PubMed ID

37185976

Citation

Russo, Roberto, et al. "Immunosuppressive Treatment for Autoimmune Blistering Diseases Does Not Impair Production of Neutralizing Antibodies After "booster" Dose of COVID-19 Vaccine." International Journal of Dermatology, vol. 62, no. 7, 2023, pp. 847-849.
Russo R, Capurro N, Cozzani E, et al. Immunosuppressive treatment for autoimmune blistering diseases does not impair production of neutralizing antibodies after "booster" dose of COVID-19 vaccine. Int J Dermatol. 2023;62(7):847-849.
Russo, R., Capurro, N., Cozzani, E., Gasparini, G., Canepa, P., & Parodi, A. (2023). Immunosuppressive treatment for autoimmune blistering diseases does not impair production of neutralizing antibodies after "booster" dose of COVID-19 vaccine. International Journal of Dermatology, 62(7), 847-849. https://doi.org/10.1111/ijd.16695
Russo R, et al. Immunosuppressive Treatment for Autoimmune Blistering Diseases Does Not Impair Production of Neutralizing Antibodies After "booster" Dose of COVID-19 Vaccine. Int J Dermatol. 2023;62(7):847-849. PubMed PMID: 37185976.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immunosuppressive treatment for autoimmune blistering diseases does not impair production of neutralizing antibodies after "booster" dose of COVID-19 vaccine. AU - Russo,Roberto, AU - Capurro,Niccolὸ, AU - Cozzani,Emanuele, AU - Gasparini,Giulia, AU - Canepa,Paola, AU - Parodi,Aurora, Y1 - 2023/04/26/ PY - 2023/3/28/revised PY - 2023/2/14/received PY - 2023/4/4/accepted PY - 2023/6/14/medline PY - 2023/5/15/pubmed PY - 2023/5/15/entrez SP - 847 EP - 849 JF - International journal of dermatology JO - Int J Dermatol VL - 62 IS - 7 N2 - Since vaccines against COVID-19 are available, it has been debated if immunosuppressed patients with autoimmune blistering diseases (AIBDs) should be advised to interrupt the immunosuppressive therapy before receiving the vaccine, with consequent risk to experience a flare of disease. In the present study, we measured the neutralizing antibodies production after anti-SARS-CoV-2 vaccination in patients with AIBDs on immunosuppressive treatment, compared to healthy controls. Our results give strength to the hypothesis that these patients do not need to discontinue their therapy to produce effective levels of neutralizing antibodies, in other words to achieve successful protection. SN - 1365-4632 UR - https://www.unboundmedicine.com/medline/citation/37185976/Immunosuppressive_treatment_for_autoimmune_blistering_diseases_does_not_impair_production_of_neutralizing_antibodies_after_"booster"_dose_of_COVID-19_vaccine. DB - PRIME DP - Unbound Medicine ER -