TY - JOUR T1 - A Rare Case of New-Onset Crohn's Disease in a Patient With Chronic Palmoplantar Pustulosis. AU - Tanida,Satoshi, AU - Yoshii,Shoichiro, AU - Kubo,Ryoji, AU - Takahama,Takuya, AU - Sasoh,Shun, AU - Kubota,Yoshimasa, AU - Ban,Tesshin, AU - Ando,Tomoaki, AU - Nakamura,Makoto, AU - Joh,Takashi, Y1 - 2023/04/28/ PY - 2023/02/25/received PY - 2023/04/12/accepted PY - 2023/5/16/medline PY - 2023/5/16/pubmed PY - 2023/5/15/entrez KW - Clinical remission KW - Generalized pustular psoriasis KW - New-onset Crohn’s disease KW - Palmoplantar pustulosis KW - Ustekinumab SP - 243 EP - 249 JF - Journal of clinical medicine research JO - J Clin Med Res VL - 15 IS - 4 N2 - A 44-year-old woman who had been diagnosed with palmoplantar pustulosis (PPP) at 34 years old was diagnosed with moderate Crohn's disease (CD) based on endoscopic, radiological, and pathological findings. As treatment with corticosteroids, ultraviolet, and cyclosporin had achieved partial response, PPP had been refractory in a chronic continuous state. Oral prednisolone was initially started to treat CD, but clinical remission was not achieved. Intravenous ustekinumab was subsequently started at 260 mg for clinical remission of CD. Eight weeks after starting ustekinumab, clinical remission and mucosal healing were achieved and PPP manifestations on the palms and soles were markedly improved. Ustekinumab appears to offer an effective therapeutic option for patients with PPP but has yet to be approved for this induction in Japan. CD is a rare gastrointestinal involvement in PPP patients that requires attention. SN - 1918-3003 UR - https://www.unboundmedicine.com/medline/citation/37187712/A_Rare_Case_of_New_Onset_Crohn's_Disease_in_a_Patient_With_Chronic_Palmoplantar_Pustulosis_ DB - PRIME DP - Unbound Medicine ER -