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Mpox virus Clade IIb detection in the air.
J Med Virol. 2023 05; 95(5):e28775.JM

Abstract

Mpox is a viral zoonotic disease endemic in Central and West Africa that is caused by the Mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. The clinical manifestations of mpox infection are milder than those of smallpox, and the incubation time of mpox varies from 5 to 21 days. Since May 2022, the mpox outbreak (formerly known as monkeypox) has suddenly and unexpectedly spread in non-endemic countries, suggesting that there may have been some undetected transmissions. Based on molecular analysis, there are two major genetic clades that represent the mpox virus: Clade I (formerly the Congo Basin clade OR the Central African clade) and Clade II (formerly the West African clade). It is believed that people who are asymptomatic or paucisymptomatic may spread the mpox virus. Infectious viruses cannot be distinguished by PCR testing; therefore, virus culture should be carried out. Recent evidence regarding the detection of the mpox virus (Clade IIb) in air samples collected from the patient's environment during the 2022 mpox outbreak was reviewed. Further studies are needed to evaluate the extent to which the presence of mpox virus DNA in the air could affect immunocompromised patients in healthcare facilities, and further epidemiological studies are crucial, especially in Africa.

Authors+Show Affiliations

National Food Safety Authority (NFSA), Aswan Branch, Aswan, Egypt. Ministry of Tourism and Antiquities, Aswan Office, Aswan, Egypt.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

37212310

Citation

Saied, AbdulRahman A.. "Mpox Virus Clade IIb Detection in the Air." Journal of Medical Virology, vol. 95, no. 5, 2023, pp. e28775.
Saied AA. Mpox virus Clade IIb detection in the air. J Med Virol. 2023;95(5):e28775.
Saied, A. A. (2023). Mpox virus Clade IIb detection in the air. Journal of Medical Virology, 95(5), e28775. https://doi.org/10.1002/jmv.28775
Saied AA. Mpox Virus Clade IIb Detection in the Air. J Med Virol. 2023;95(5):e28775. PubMed PMID: 37212310.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mpox virus Clade IIb detection in the air. A1 - Saied,AbdulRahman A, PY - 2023/04/17/revised PY - 2023/02/06/received PY - 2023/04/22/accepted PY - 2023/5/23/medline PY - 2023/5/22/pubmed PY - 2023/5/22/entrez KW - Africa KW - Clade I KW - Clade IIb KW - Mpox virus KW - air detection KW - infection-competent virus KW - resurgence KW - transmission SP - e28775 EP - e28775 JF - Journal of medical virology JO - J Med Virol VL - 95 IS - 5 N2 - Mpox is a viral zoonotic disease endemic in Central and West Africa that is caused by the Mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. The clinical manifestations of mpox infection are milder than those of smallpox, and the incubation time of mpox varies from 5 to 21 days. Since May 2022, the mpox outbreak (formerly known as monkeypox) has suddenly and unexpectedly spread in non-endemic countries, suggesting that there may have been some undetected transmissions. Based on molecular analysis, there are two major genetic clades that represent the mpox virus: Clade I (formerly the Congo Basin clade OR the Central African clade) and Clade II (formerly the West African clade). It is believed that people who are asymptomatic or paucisymptomatic may spread the mpox virus. Infectious viruses cannot be distinguished by PCR testing; therefore, virus culture should be carried out. Recent evidence regarding the detection of the mpox virus (Clade IIb) in air samples collected from the patient's environment during the 2022 mpox outbreak was reviewed. Further studies are needed to evaluate the extent to which the presence of mpox virus DNA in the air could affect immunocompromised patients in healthcare facilities, and further epidemiological studies are crucial, especially in Africa. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/37212310/Mpox_virus_Clade_IIb_detection_in_the_air_ DB - PRIME DP - Unbound Medicine ER -