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Isolation and hypoglycemic activity of eleutherans A, B, C, D, E, F, and G: glycans of Eleutherococcus senticosus roots.

Abstract

Intraperitoneal injection of an aqueous extract of the crude drug "shigoka" (Siberian ginseng), Eleutherococcus senticosus roots, remarkably diminished plasma-sugar level in mice. Fractionation of the extract by monitoring the activity yielded seven glycans, eleutherans A, B, C, D, E, F, and G, which exerted marked hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.

Authors

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Source

MeSH

Animals
Carbohydrates
Chemical Phenomena
Chemistry
Chromatography, DEAE-Cellulose
Electrophoresis, Paper
Electrophoresis, Polyacrylamide Gel
Hypoglycemic Agents
Male
Mice
Mice, Inbred Strains
Panax
Plants, Medicinal
Polysaccharides

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3734812

Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isolation and hypoglycemic activity of eleutherans A, B, C, D, E, F, and G: glycans of Eleutherococcus senticosus roots. AU - Hikino,H, AU - Takahashi,M, AU - Otake,K, AU - Konno,C, PY - 1986/3/1/pubmed PY - 1986/3/1/medline PY - 1986/3/1/entrez SP - 293 EP - 7 JF - Journal of natural products JO - J. Nat. Prod. VL - 49 IS - 2 N2 - Intraperitoneal injection of an aqueous extract of the crude drug "shigoka" (Siberian ginseng), Eleutherococcus senticosus roots, remarkably diminished plasma-sugar level in mice. Fractionation of the extract by monitoring the activity yielded seven glycans, eleutherans A, B, C, D, E, F, and G, which exerted marked hypoglycemic effects in normal and alloxan-induced hyperglycemic mice. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/3734812/Isolation_and_hypoglycemic_activity_of_eleutherans_A_B_C_D_E_F_and_G:_glycans_of_Eleutherococcus_senticosus_roots_ L2 - https://medlineplus.gov/diabetesmedicines.html DB - PRIME DP - Unbound Medicine ER -