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The role of arteriovenous shunts in the pathogenesis of varicose veins.
J Vasc Surg. 1986 Aug; 4(2):124-8.JV

Abstract

Varicose veins and venous insufficiency are causes of significant morbidity. In North America 10% to 17% of the adult population is affected, an incidence 10 times that of arterial disease. Despite this, origin and mechanism of disease remain obscure. This study was designed to illustrate the presence of patent arteriovenous shunts in the varicosed limb and to assess their role. Twenty-eight women and twenty-one men with primary varicose veins were studied. Thirty-six men and seven women without venous disease served as a control group. Blood samples were collected from an arm vein and a limb varicosity in the study group along with an arterial blood sample. Blood samples were also drawn from an arm vein and the femoral vein in the control group along with an arterial blood sample. Venous partial oxygen pressure (PVO2) and hemoglobin saturation (HbSat) were measured and venous oxygen content (CVO2) calculated. Mean values were then obtained and statistical comparisons made between each group. A statistically significant increase (p less than 0.001) in all three parameters--PVO2, HbSat, and CVO2--was demonstrated in the patients' limbs with varicose veins, consistent with a functioning arteriovenous shunt.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3735566

Citation

Baron, H C., and S Cassaro. "The Role of Arteriovenous Shunts in the Pathogenesis of Varicose Veins." Journal of Vascular Surgery, vol. 4, no. 2, 1986, pp. 124-8.
Baron HC, Cassaro S. The role of arteriovenous shunts in the pathogenesis of varicose veins. J Vasc Surg. 1986;4(2):124-8.
Baron, H. C., & Cassaro, S. (1986). The role of arteriovenous shunts in the pathogenesis of varicose veins. Journal of Vascular Surgery, 4(2), 124-8.
Baron HC, Cassaro S. The Role of Arteriovenous Shunts in the Pathogenesis of Varicose Veins. J Vasc Surg. 1986;4(2):124-8. PubMed PMID: 3735566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of arteriovenous shunts in the pathogenesis of varicose veins. AU - Baron,H C, AU - Cassaro,S, PY - 1986/8/1/pubmed PY - 2001/9/6/medline PY - 1986/8/1/entrez SP - 124 EP - 8 JF - Journal of vascular surgery JO - J Vasc Surg VL - 4 IS - 2 N2 - Varicose veins and venous insufficiency are causes of significant morbidity. In North America 10% to 17% of the adult population is affected, an incidence 10 times that of arterial disease. Despite this, origin and mechanism of disease remain obscure. This study was designed to illustrate the presence of patent arteriovenous shunts in the varicosed limb and to assess their role. Twenty-eight women and twenty-one men with primary varicose veins were studied. Thirty-six men and seven women without venous disease served as a control group. Blood samples were collected from an arm vein and a limb varicosity in the study group along with an arterial blood sample. Blood samples were also drawn from an arm vein and the femoral vein in the control group along with an arterial blood sample. Venous partial oxygen pressure (PVO2) and hemoglobin saturation (HbSat) were measured and venous oxygen content (CVO2) calculated. Mean values were then obtained and statistical comparisons made between each group. A statistically significant increase (p less than 0.001) in all three parameters--PVO2, HbSat, and CVO2--was demonstrated in the patients' limbs with varicose veins, consistent with a functioning arteriovenous shunt. SN - 0741-5214 UR - https://www.unboundmedicine.com/medline/citation/3735566/The_role_of_arteriovenous_shunts_in_the_pathogenesis_of_varicose_veins_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0741-5214(86)90411-8 DB - PRIME DP - Unbound Medicine ER -