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Neurological complications of anticoagulation therapy: a neurologist's review.
Arch Intern Med. 1979 Feb; 139(2):217-20.AI

Abstract

Anticoagulant-induced bleeding may involve the brain, spinal cord, or peripheral nerves. It may occur with either coumarin or heparin anticoagulants, in the absence of trauma, and while prothrombin times, clotting times, or partial thromboplastin times are in accepted therapeutic ranges. Bleeding involving the brain occurs usually as a subdural hematoma, with intracerebral or subarachnoid hemorrhages occurring less frequently. There may be diagnostic problems in the recognition of these anticoagulant-related subdural hematomas. The spinal cord involvement usually appears in the form of an extradural hematoma. This condition can progress rapidly, and prompt recognition of its presence, localization with myelography, and laminectomy for surgical evacuation are necessary. The peripheral nerve most frequently compressed is the femoral nerve, due to bleeding into the iliacus muscle. Other nerves can be involved, and surgical evacuation may be necessary at times.

Authors

No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

373657

Citation

Silverstein, A. "Neurological Complications of Anticoagulation Therapy: a Neurologist's Review." Archives of Internal Medicine, vol. 139, no. 2, 1979, pp. 217-20.
Silverstein A. Neurological complications of anticoagulation therapy: a neurologist's review. Arch Intern Med. 1979;139(2):217-20.
Silverstein, A. (1979). Neurological complications of anticoagulation therapy: a neurologist's review. Archives of Internal Medicine, 139(2), 217-20.
Silverstein A. Neurological Complications of Anticoagulation Therapy: a Neurologist's Review. Arch Intern Med. 1979;139(2):217-20. PubMed PMID: 373657.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurological complications of anticoagulation therapy: a neurologist's review. A1 - Silverstein,A, PY - 1979/2/1/pubmed PY - 1979/2/1/medline PY - 1979/2/1/entrez SP - 217 EP - 20 JF - Archives of internal medicine JO - Arch Intern Med VL - 139 IS - 2 N2 - Anticoagulant-induced bleeding may involve the brain, spinal cord, or peripheral nerves. It may occur with either coumarin or heparin anticoagulants, in the absence of trauma, and while prothrombin times, clotting times, or partial thromboplastin times are in accepted therapeutic ranges. Bleeding involving the brain occurs usually as a subdural hematoma, with intracerebral or subarachnoid hemorrhages occurring less frequently. There may be diagnostic problems in the recognition of these anticoagulant-related subdural hematomas. The spinal cord involvement usually appears in the form of an extradural hematoma. This condition can progress rapidly, and prompt recognition of its presence, localization with myelography, and laminectomy for surgical evacuation are necessary. The peripheral nerve most frequently compressed is the femoral nerve, due to bleeding into the iliacus muscle. Other nerves can be involved, and surgical evacuation may be necessary at times. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/373657/Neurological_complications_of_anticoagulation_therapy:_a_neurologist's_review_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/139/pg/217 DB - PRIME DP - Unbound Medicine ER -