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Atypical polypoid adenomyoma of the uterus. A report of 27 cases.
Am J Clin Pathol. 1986 Aug; 86(2):139-45.AJ

Abstract

Twenty-seven atypical polypoid adenomyomas of the uterus were reviewed. The tumors occurred in women ages 21-53 (average 39.7) years old, who presented with abnormal uterine bleeding in most cases. Two of the patients had Turner's syndrome. The adenomyomas most frequently involved the lower uterine segment, measured up to 6 (average 1.9) cm in greatest dimension, and were characteristically polypoid and well circumscribed. Microscopic examination disclosed endometrial glands with varying degrees of hyperplasia and atypicality up to the appearance of carcinoma in situ within neoplastic smooth muscle. Squamous differentiation was common within the glands; the smooth muscle occasionally was atypical. Follow-up data suggested that the lesion is benign, although it persisted in two patients treated by curettage alone. Atypical polypoid adenomyomas should be distinguished from endometrial carcinomas and other malignant uterine neoplasms with which they are often confused, particularly in curettage specimens.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3739968

Citation

Young, R H., et al. "Atypical Polypoid Adenomyoma of the Uterus. a Report of 27 Cases." American Journal of Clinical Pathology, vol. 86, no. 2, 1986, pp. 139-45.
Young RH, Treger T, Scully RE. Atypical polypoid adenomyoma of the uterus. A report of 27 cases. Am J Clin Pathol. 1986;86(2):139-45.
Young, R. H., Treger, T., & Scully, R. E. (1986). Atypical polypoid adenomyoma of the uterus. A report of 27 cases. American Journal of Clinical Pathology, 86(2), 139-45.
Young RH, Treger T, Scully RE. Atypical Polypoid Adenomyoma of the Uterus. a Report of 27 Cases. Am J Clin Pathol. 1986;86(2):139-45. PubMed PMID: 3739968.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical polypoid adenomyoma of the uterus. A report of 27 cases. AU - Young,R H, AU - Treger,T, AU - Scully,R E, PY - 1986/8/1/pubmed PY - 1986/8/1/medline PY - 1986/8/1/entrez SP - 139 EP - 45 JF - American journal of clinical pathology JO - Am J Clin Pathol VL - 86 IS - 2 N2 - Twenty-seven atypical polypoid adenomyomas of the uterus were reviewed. The tumors occurred in women ages 21-53 (average 39.7) years old, who presented with abnormal uterine bleeding in most cases. Two of the patients had Turner's syndrome. The adenomyomas most frequently involved the lower uterine segment, measured up to 6 (average 1.9) cm in greatest dimension, and were characteristically polypoid and well circumscribed. Microscopic examination disclosed endometrial glands with varying degrees of hyperplasia and atypicality up to the appearance of carcinoma in situ within neoplastic smooth muscle. Squamous differentiation was common within the glands; the smooth muscle occasionally was atypical. Follow-up data suggested that the lesion is benign, although it persisted in two patients treated by curettage alone. Atypical polypoid adenomyomas should be distinguished from endometrial carcinomas and other malignant uterine neoplasms with which they are often confused, particularly in curettage specimens. SN - 0002-9173 UR - https://www.unboundmedicine.com/medline/citation/3739968/Atypical_polypoid_adenomyoma_of_the_uterus__A_report_of_27_cases_ L2 - https://academic.oup.com/ajcp/article-lookup/doi/10.1093/ajcp/86.2.139 DB - PRIME DP - Unbound Medicine ER -