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Red cell distribution width in sickle cell disease.
Ann Clin Lab Sci. 1986 Jul-Aug; 16(4):274-7.AC

Abstract

Red cell distribution width (RDW), an electronically determined index of anisocytosis, was examined in 60 patients with sickle cell anemia (Hb SS), 28 patients with hemoglobin sickle cell (SC) disease, and seven patients with sickle cell-beta(+) thalassemia (S-thal). All patients were adults and in the steady state of their disease. The RDW was greater in sickle cell patients than in 39 healthy, age and race matched controls without hemoglobinopathy (Hb AA). Patients with sickle cell anemia had higher mean RDW than those with Hb SC disease or with S-thal. The mean RDWs in the latter two disorders were not significantly different. In SS patients, the RDW correlated significantly with the degree of anemia and reticulocytosis. A group of 18 SS patients was studied while in acute painful crisis. Their mean RDW was not different from that in the steady state. Mean WBC and red cell volume, however, were significantly higher during pain crisis.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3740796

Citation

Webster, P, and O Castro. "Red Cell Distribution Width in Sickle Cell Disease." Annals of Clinical and Laboratory Science, vol. 16, no. 4, 1986, pp. 274-7.
Webster P, Castro O. Red cell distribution width in sickle cell disease. Ann Clin Lab Sci. 1986;16(4):274-7.
Webster, P., & Castro, O. (1986). Red cell distribution width in sickle cell disease. Annals of Clinical and Laboratory Science, 16(4), 274-7.
Webster P, Castro O. Red Cell Distribution Width in Sickle Cell Disease. Ann Clin Lab Sci. 1986 Jul-Aug;16(4):274-7. PubMed PMID: 3740796.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Red cell distribution width in sickle cell disease. AU - Webster,P, AU - Castro,O, PY - 1986/7/1/pubmed PY - 1986/7/1/medline PY - 1986/7/1/entrez SP - 274 EP - 7 JF - Annals of clinical and laboratory science JO - Ann. Clin. Lab. Sci. VL - 16 IS - 4 N2 - Red cell distribution width (RDW), an electronically determined index of anisocytosis, was examined in 60 patients with sickle cell anemia (Hb SS), 28 patients with hemoglobin sickle cell (SC) disease, and seven patients with sickle cell-beta(+) thalassemia (S-thal). All patients were adults and in the steady state of their disease. The RDW was greater in sickle cell patients than in 39 healthy, age and race matched controls without hemoglobinopathy (Hb AA). Patients with sickle cell anemia had higher mean RDW than those with Hb SC disease or with S-thal. The mean RDWs in the latter two disorders were not significantly different. In SS patients, the RDW correlated significantly with the degree of anemia and reticulocytosis. A group of 18 SS patients was studied while in acute painful crisis. Their mean RDW was not different from that in the steady state. Mean WBC and red cell volume, however, were significantly higher during pain crisis. SN - 0091-7370 UR - https://www.unboundmedicine.com/medline/citation/3740796/Red_cell_distribution_width_in_sickle_cell_disease_ L2 - http://www.diseaseinfosearch.org/result/6589 DB - PRIME DP - Unbound Medicine ER -