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Forensic toxicologic analysis of methamphetamine and amphetamine in body materials by gas chromatography/mass spectrometry.
Z Rechtsmed. 1986; 96(2):93-104.ZR

Abstract

Qualitative and quantitative analysis of methamphetamine and amphetamine in biologic materials was carried out by gas chromatography/mass spectrometry. A deuterium-labeled methamphetamine was employed as an internal standard with a detection limit of 50 pg and absolute stability and reproducibility. Blood was found to be the best material for estimation of the toxicity of the stimulant drug. It can be replaced by muscle which contains methamphetamine concentrations close to those of blood. The authors' classification of the toxic blood levels of methamphetamine from therapeutic to fatal doses was confirmed by additional data obtained from new case studies.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3751348

Citation

Hara, K, et al. "Forensic Toxicologic Analysis of Methamphetamine and Amphetamine in Body Materials By Gas Chromatography/mass Spectrometry." Zeitschrift Fur Rechtsmedizin. Journal of Legal Medicine, vol. 96, no. 2, 1986, pp. 93-104.
Hara K, Nagata T, Kimura K. Forensic toxicologic analysis of methamphetamine and amphetamine in body materials by gas chromatography/mass spectrometry. Z Rechtsmed. 1986;96(2):93-104.
Hara, K., Nagata, T., & Kimura, K. (1986). Forensic toxicologic analysis of methamphetamine and amphetamine in body materials by gas chromatography/mass spectrometry. Zeitschrift Fur Rechtsmedizin. Journal of Legal Medicine, 96(2), 93-104.
Hara K, Nagata T, Kimura K. Forensic Toxicologic Analysis of Methamphetamine and Amphetamine in Body Materials By Gas Chromatography/mass Spectrometry. Z Rechtsmed. 1986;96(2):93-104. PubMed PMID: 3751348.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Forensic toxicologic analysis of methamphetamine and amphetamine in body materials by gas chromatography/mass spectrometry. AU - Hara,K, AU - Nagata,T, AU - Kimura,K, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 93 EP - 104 JF - Zeitschrift fur Rechtsmedizin. Journal of legal medicine JO - Z. Rechtsmed. VL - 96 IS - 2 N2 - Qualitative and quantitative analysis of methamphetamine and amphetamine in biologic materials was carried out by gas chromatography/mass spectrometry. A deuterium-labeled methamphetamine was employed as an internal standard with a detection limit of 50 pg and absolute stability and reproducibility. Blood was found to be the best material for estimation of the toxicity of the stimulant drug. It can be replaced by muscle which contains methamphetamine concentrations close to those of blood. The authors' classification of the toxic blood levels of methamphetamine from therapeutic to fatal doses was confirmed by additional data obtained from new case studies. SN - 0044-3433 UR - https://www.unboundmedicine.com/medline/citation/3751348/Forensic_toxicologic_analysis_of_methamphetamine_and_amphetamine_in_body_materials_by_gas_chromatography/mass_spectrometry_ L2 - https://medlineplus.gov/methamphetamine.html DB - PRIME DP - Unbound Medicine ER -
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