Tags

Type your tag names separated by a space and hit enter

Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review.
Int J Med Mushrooms. 2023; 25(8):1-17.IJ

Abstract

Mushrooms are full of nutrition and have beneficial properties for human health. Polysaccharides are the main component of edible and medicinal mushrooms, especially β-glucans, which have attracted much more attention for their complex structure and diverse biological activities. Among all the diverse medicinal activities of mushroom polysaccharides, antitumor and immune-enhancing activities are two excellent bioactivities that have much more potential and deserve application. Their bioactivities are highly dependent on their structural features, including molecular weight, monosaccharide composition, degree of branching, type and configuration of glycosidic bonds, substituent pattern, and chain conformation. This review summarizes the current method for obtaining polysaccharides from mushrooms, chemical characterizations of the structures and their roles in immune and antitumor activities. In addition, the methods for preparation of the polysaccharide derivatives and the potential medicinal clinical application are also discussed in this review, which may provide new guidance for mushroom polysaccharide development.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Dong Y
School of Food and Biological Engineering, Institute of Food Physical Processing, International Joint Research Center for Food Physical Processing, Jiangsu University, No. 301 Xuefu Road, Zhenjiang 212013, P.R. China; Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science & Technology Center (NASC), 9 Hupan West Road, Tianfu New Area, Chengdu, 610000, P.R. China.
Wang T
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science & Technology Center (NASC), 9 Hupan West Road, Tianfu New Area, Chengdu, 610000 P.R. China.
Zhao J
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science & Technology Center (NASC), 9 Hupan West Road, Tianfu New Area, Chengdu, 610000, P.R. China.
Gan B
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science & Technology Center (NASC), 9 Hupan West Road, Tianfu New Area, Chengdu, 610000 P.R. China.
Feng R
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science & Technology Center (NASC), 9 Hupan West Road, Tianfu New Area, Chengdu, 610000, P.R. China.
Miao R
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science & Technology Center (NASC), 9 Hupan West Road, Tianfu New Area, Chengdu, 610000, P.R. China.

MeSH

HumansAgaricalesPolysaccharidesbeta-GlucansMolecular WeightMonosaccharides

Pub Type(s)

Review
Journal Article

Language

eng

PubMed ID

37560886

Citation

Dong, Yating, et al. "Polysaccharides Derived From Mushrooms in Immune and Antitumor Activity: a Review." International Journal of Medicinal Mushrooms, vol. 25, no. 8, 2023, pp. 1-17.
Dong Y, Wang T, Zhao J, et al. Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review. Int J Med Mushrooms. 2023;25(8):1-17.
Dong, Y., Wang, T., Zhao, J., Gan, B., Feng, R., & Miao, R. (2023). Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review. International Journal of Medicinal Mushrooms, 25(8), 1-17. https://doi.org/10.1615/IntJMedMushrooms.2023049062
Dong Y, et al. Polysaccharides Derived From Mushrooms in Immune and Antitumor Activity: a Review. Int J Med Mushrooms. 2023;25(8):1-17. PubMed PMID: 37560886.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review. AU - Dong,Yating, AU - Wang,Tao, AU - Zhao,Jin, AU - Gan,Bingcheng, AU - Feng,Rencai, AU - Miao,Renyun, PY - 2023/8/11/medline PY - 2023/8/10/pubmed PY - 2023/8/10/entrez SP - 1 EP - 17 JF - International journal of medicinal mushrooms JO - Int J Med Mushrooms VL - 25 IS - 8 N2 - Mushrooms are full of nutrition and have beneficial properties for human health. Polysaccharides are the main component of edible and medicinal mushrooms, especially β-glucans, which have attracted much more attention for their complex structure and diverse biological activities. Among all the diverse medicinal activities of mushroom polysaccharides, antitumor and immune-enhancing activities are two excellent bioactivities that have much more potential and deserve application. Their bioactivities are highly dependent on their structural features, including molecular weight, monosaccharide composition, degree of branching, type and configuration of glycosidic bonds, substituent pattern, and chain conformation. This review summarizes the current method for obtaining polysaccharides from mushrooms, chemical characterizations of the structures and their roles in immune and antitumor activities. In addition, the methods for preparation of the polysaccharide derivatives and the potential medicinal clinical application are also discussed in this review, which may provide new guidance for mushroom polysaccharide development. SN - 1940-4344 UR - https://www.unboundmedicine.com/medline/citation/37560886/Polysaccharides_Derived_from_Mushrooms_in_Immune_and_Antitumor_Activity:_A_Review_ DB - PRIME DP - Unbound Medicine ER -