Tags

Type your tag names separated by a space and hit enter

Antineoplastic agents from higher plants: application of tandem mass spectrometry to xanthones from Psorospermum febrifugum.
J Nat Prod. 1986 May-Jun; 49(3):412-23.JN

Abstract

Psorospermum febrifugum was examined using tandem ms for the presence of 3',4'-deoxypsorospermin-4'-chloro-3'-ol and psorospermin. Collision-induced dissociation at both high and low energy is used to bring about fragmentation. Daughter spectra were interpreted to reveal characteristic fragmentations for both compounds. Examination of the authentic compounds, various extracts of the plant root, and the plant root material itself established that psorospermin occurs naturally in the plant. The data also suggest the presence of the chlorohydrin in the root, as well as establishing its presence in the root extracts. The detection of neutral compounds in complex mixtures by tandem ms is facilitated if comparisons can be made between spectra resulting from different methods of ionization and excitation.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3760881

Citation

Pachuta, R R., et al. "Antineoplastic Agents From Higher Plants: Application of Tandem Mass Spectrometry to Xanthones From Psorospermum Febrifugum." Journal of Natural Products, vol. 49, no. 3, 1986, pp. 412-23.
Pachuta RR, Cooks RG, Cassady JM, et al. Antineoplastic agents from higher plants: application of tandem mass spectrometry to xanthones from Psorospermum febrifugum. J Nat Prod. 1986;49(3):412-23.
Pachuta, R. R., Cooks, R. G., Cassady, J. M., Cong, P., McCloud, T. G., & Chang, C. J. (1986). Antineoplastic agents from higher plants: application of tandem mass spectrometry to xanthones from Psorospermum febrifugum. Journal of Natural Products, 49(3), 412-23.
Pachuta RR, et al. Antineoplastic Agents From Higher Plants: Application of Tandem Mass Spectrometry to Xanthones From Psorospermum Febrifugum. J Nat Prod. 1986 May-Jun;49(3):412-23. PubMed PMID: 3760881.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antineoplastic agents from higher plants: application of tandem mass spectrometry to xanthones from Psorospermum febrifugum. AU - Pachuta,R R, AU - Cooks,R G, AU - Cassady,J M, AU - Cong,P, AU - McCloud,T G, AU - Chang,C J, PY - 1986/5/1/pubmed PY - 1986/5/1/medline PY - 1986/5/1/entrez SP - 412 EP - 23 JF - Journal of natural products JO - J Nat Prod VL - 49 IS - 3 N2 - Psorospermum febrifugum was examined using tandem ms for the presence of 3',4'-deoxypsorospermin-4'-chloro-3'-ol and psorospermin. Collision-induced dissociation at both high and low energy is used to bring about fragmentation. Daughter spectra were interpreted to reveal characteristic fragmentations for both compounds. Examination of the authentic compounds, various extracts of the plant root, and the plant root material itself established that psorospermin occurs naturally in the plant. The data also suggest the presence of the chlorohydrin in the root, as well as establishing its presence in the root extracts. The detection of neutral compounds in complex mixtures by tandem ms is facilitated if comparisons can be made between spectra resulting from different methods of ionization and excitation. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/3760881/Antineoplastic_agents_from_higher_plants:_application_of_tandem_mass_spectrometry_to_xanthones_from_Psorospermum_febrifugum_ L2 - https://www.lens.org/lens/search/patent/list?q=citation_id:3760881 DB - PRIME DP - Unbound Medicine ER -