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Syrian Golden Hamster Model for Nipah Virus Infection.
Methods Mol Biol. 2023; 2682:219-229.MM

Abstract

Small rodent animal models that recapitulate the symptomology and pathology of the human disease caused by Nipah virus (NiV) are crucial not only to study virus-induced disease but also a critical component for the development of vaccine and therapeutic candidates. The Syrian golden hamster is the most commonly used small animal model for NiV and develops clinical symptoms and pathologies that closely resemble NiV disease in humans. In this chapter, we describe standard techniques used to infect hamsters and conduct evaluation of therapeutics and vaccine candidates.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Juelich T
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Smith J
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Freiberg AN
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA. anfreibe@utmb.edu.

MeSH

AnimalsCricetinaeHumansHenipavirus InfectionsMesocricetusModels, Animal

Pub Type(s)

Journal Article

Language

eng

PubMed ID

37610585

Citation

Juelich, Terry, et al. "Syrian Golden Hamster Model for Nipah Virus Infection." Methods in Molecular Biology (Clifton, N.J.), vol. 2682, 2023, pp. 219-229.
Juelich T, Smith J, Freiberg AN. Syrian Golden Hamster Model for Nipah Virus Infection. Methods Mol Biol. 2023;2682:219-229.
Juelich, T., Smith, J., & Freiberg, A. N. (2023). Syrian Golden Hamster Model for Nipah Virus Infection. Methods in Molecular Biology (Clifton, N.J.), 2682, 219-229. https://doi.org/10.1007/978-1-0716-3283-3_16
Juelich T, Smith J, Freiberg AN. Syrian Golden Hamster Model for Nipah Virus Infection. Methods Mol Biol. 2023;2682:219-229. PubMed PMID: 37610585.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Syrian Golden Hamster Model for Nipah Virus Infection. AU - Juelich,Terry, AU - Smith,Jennifer, AU - Freiberg,Alexander N, PY - 2023/8/24/medline PY - 2023/8/23/pubmed PY - 2023/8/23/entrez KW - Antiviral KW - Nipah virus KW - Pathogenicity KW - Small animal model KW - Syrian golden hamster KW - Vaccine SP - 219 EP - 229 JF - Methods in molecular biology (Clifton, N.J.) JO - Methods Mol Biol VL - 2682 N2 - Small rodent animal models that recapitulate the symptomology and pathology of the human disease caused by Nipah virus (NiV) are crucial not only to study virus-induced disease but also a critical component for the development of vaccine and therapeutic candidates. The Syrian golden hamster is the most commonly used small animal model for NiV and develops clinical symptoms and pathologies that closely resemble NiV disease in humans. In this chapter, we describe standard techniques used to infect hamsters and conduct evaluation of therapeutics and vaccine candidates. SN - 1940-6029 UR - https://www.unboundmedicine.com/medline/citation/37610585/Syrian_Golden_Hamster_Model_for_Nipah_Virus_Infection_ DB - PRIME DP - Unbound Medicine ER -