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Desorption of sulfamethoxazole from polyamide 6 microplastics: Environmental factors, simulated gastrointestinal fluids, and desorption mechanisms.
Ecotoxicol Environ Saf. 2023 Oct 01; 264:115400.EE

Abstract

Microplastics (MPs) can enrich pollutants after being released into the environment, and the contaminants-loaded MPs are usually ingested by organisms, resulting in a potential dual biotoxic effect. In this paper, the adsorption behavior of Sulfamethoxazole (SMX) on Polyamide 6 (PA6) MPs was systematically investigated and simulated by the kinetic and isotherm models. The effect of environmental conditions (pH, salinity) on the adsorption process was studied, and the desorption behavior of SMX-loaded PA6 MPs was focused on simulating the seawater, ultrapure water, gastric and intestinal fluids. We found that lower pH and solubilization of SMX by gastrointestinal components (bovine serum albumin (BSA), sodium taurocholate (NaT), and pepsin) can reduce the electrostatic interaction between the surface charge of PA6 MPs and SMX. The result will lead to an increase in the desorption capacity of SMX-loaded PA6 MPs in gastrointestinal fluids and therefore will provide a reasonable mechanism for the desorption of SMX-loaded PA6 MPs in the gastrointestinal fluids. This study will provide a theoretical reference for studying the desorption behavior of SMX-loaded PA6 MPs under gastrointestinal conditions.

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Authors+Show Affiliations

Wang K
Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, School of chemical engineering and technology, Xinjiang University, Urumqi, China.
Wang K
Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, School of chemical engineering and technology, Xinjiang University, Urumqi, China.
Chen Y
Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, School of chemical engineering and technology, Xinjiang University, Urumqi, China.
Liang S
Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, School of chemical engineering and technology, Xinjiang University, Urumqi, China.
Zhang Y
College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
Guo C
Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, School of chemical engineering and technology, Xinjiang University, Urumqi, China. Electronic address: gcyslw@xju.edu.cn.
Wang W
Department of Chemistry and Center for Pharmacy, University of Bergen, Bergen N-5007, Norway. Electronic address: wei.wang@uib.no.
Wang J
Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, School of chemical engineering and technology, Xinjiang University, Urumqi, China. Electronic address: awangjd@sina.cn.

MeSH

MicroplasticsPlasticsStomachSulfamethoxazole

Pub Type(s)

Journal Article

Language

eng

PubMed ID

37651796

Citation

Wang, Kefu, et al. "Desorption of Sulfamethoxazole From Polyamide 6 Microplastics: Environmental Factors, Simulated Gastrointestinal Fluids, and Desorption Mechanisms." Ecotoxicology and Environmental Safety, vol. 264, 2023, p. 115400.
Wang K, Wang K, Chen Y, et al. Desorption of sulfamethoxazole from polyamide 6 microplastics: Environmental factors, simulated gastrointestinal fluids, and desorption mechanisms. Ecotoxicol Environ Saf. 2023;264:115400.
Wang, K., Wang, K., Chen, Y., Liang, S., Zhang, Y., Guo, C., Wang, W., & Wang, J. (2023). Desorption of sulfamethoxazole from polyamide 6 microplastics: Environmental factors, simulated gastrointestinal fluids, and desorption mechanisms. Ecotoxicology and Environmental Safety, 264, 115400. https://doi.org/10.1016/j.ecoenv.2023.115400
Wang K, et al. Desorption of Sulfamethoxazole From Polyamide 6 Microplastics: Environmental Factors, Simulated Gastrointestinal Fluids, and Desorption Mechanisms. Ecotoxicol Environ Saf. 2023 Oct 1;264:115400. PubMed PMID: 37651796.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Desorption of sulfamethoxazole from polyamide 6 microplastics: Environmental factors, simulated gastrointestinal fluids, and desorption mechanisms. AU - Wang,Kefu, AU - Wang,Kangkang, AU - Chen,Yaoyao, AU - Liang,Siqi, AU - Zhang,Yi, AU - Guo,Changyan, AU - Wang,Wei, AU - Wang,Jide, Y1 - 2023/08/29/ PY - 2022/10/31/received PY - 2023/08/17/revised PY - 2023/08/20/accepted PY - 2023/9/25/medline PY - 2023/9/1/pubmed PY - 2023/8/31/entrez KW - Desorption mechanisms KW - Gastrointestinal conditions KW - Polyamide 6 microplastic KW - Sorption behavior KW - Sulfonamide antibiotics SP - 115400 EP - 115400 JF - Ecotoxicology and environmental safety JO - Ecotoxicol Environ Saf VL - 264 N2 - Microplastics (MPs) can enrich pollutants after being released into the environment, and the contaminants-loaded MPs are usually ingested by organisms, resulting in a potential dual biotoxic effect. In this paper, the adsorption behavior of Sulfamethoxazole (SMX) on Polyamide 6 (PA6) MPs was systematically investigated and simulated by the kinetic and isotherm models. The effect of environmental conditions (pH, salinity) on the adsorption process was studied, and the desorption behavior of SMX-loaded PA6 MPs was focused on simulating the seawater, ultrapure water, gastric and intestinal fluids. We found that lower pH and solubilization of SMX by gastrointestinal components (bovine serum albumin (BSA), sodium taurocholate (NaT), and pepsin) can reduce the electrostatic interaction between the surface charge of PA6 MPs and SMX. The result will lead to an increase in the desorption capacity of SMX-loaded PA6 MPs in gastrointestinal fluids and therefore will provide a reasonable mechanism for the desorption of SMX-loaded PA6 MPs in the gastrointestinal fluids. This study will provide a theoretical reference for studying the desorption behavior of SMX-loaded PA6 MPs under gastrointestinal conditions. SN - 1090-2414 UR - https://www.unboundmedicine.com/medline/citation/37651796/Desorption_of_sulfamethoxazole_from_polyamide_6_microplastics:_Environmental_factors_simulated_gastrointestinal_fluids_and_desorption_mechanisms_ DB - PRIME DP - Unbound Medicine ER -