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Risk factors in calcium stone disease of the urinary tract.

Abstract

The concept that calcium stone formation may be explained on the basis of a number of risk factors is developed. The main risk factors involved are shown to be calcium, oxalate, pH, acid mucopolysaccharides and uric acid. A method is described for calculating and combining the individual risk factors into a measure of the "relative probability" of forming stones (PSF). PSF values are generally lower in normal subjects than in stone-formers. Amongst the normals, PSF values are lower in children and women than in men. Recurrent stone-formers have the highest PSF values and these correlate well with the severity of the diseases as defined by the stone episode rate of the patient. Single stone-formers have PSF values intermediate between those of normal men and those of recurrent stone-formers.

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  • Authors

    , , , ,

    Source

    British journal of urology 50:7 1978 Dec pg 449-54

    MeSH

    Adult
    Calcium Oxalate
    Calcium Phosphates
    Child
    Female
    Glycosaminoglycans
    Humans
    Hydrogen-Ion Concentration
    Male
    Methods
    Risk
    Uric Acid
    Urinary Calculi

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    37975

    Citation

    Robertson, W G., et al. "Risk Factors in Calcium Stone Disease of the Urinary Tract." British Journal of Urology, vol. 50, no. 7, 1978, pp. 449-54.
    Robertson WG, Peacock M, Heyburn PJ, et al. Risk factors in calcium stone disease of the urinary tract. Br J Urol. 1978;50(7):449-54.
    Robertson, W. G., Peacock, M., Heyburn, P. J., Marshall, D. H., & Clark, P. B. (1978). Risk factors in calcium stone disease of the urinary tract. British Journal of Urology, 50(7), pp. 449-54.
    Robertson WG, et al. Risk Factors in Calcium Stone Disease of the Urinary Tract. Br J Urol. 1978;50(7):449-54. PubMed PMID: 37975.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Risk factors in calcium stone disease of the urinary tract. AU - Robertson,W G, AU - Peacock,M, AU - Heyburn,P J, AU - Marshall,D H, AU - Clark,P B, PY - 1978/12/1/pubmed PY - 1978/12/1/medline PY - 1978/12/1/entrez SP - 449 EP - 54 JF - British journal of urology JO - Br J Urol VL - 50 IS - 7 N2 - The concept that calcium stone formation may be explained on the basis of a number of risk factors is developed. The main risk factors involved are shown to be calcium, oxalate, pH, acid mucopolysaccharides and uric acid. A method is described for calculating and combining the individual risk factors into a measure of the "relative probability" of forming stones (PSF). PSF values are generally lower in normal subjects than in stone-formers. Amongst the normals, PSF values are lower in children and women than in men. Recurrent stone-formers have the highest PSF values and these correlate well with the severity of the diseases as defined by the stone episode rate of the patient. Single stone-formers have PSF values intermediate between those of normal men and those of recurrent stone-formers. SN - 0007-1331 UR - https://www.unboundmedicine.com/medline/citation/37975/Risk_factors_in_calcium_stone_disease_of_the_urinary_tract_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-1331&date=1978&volume=50&issue=7&spage=449 DB - PRIME DP - Unbound Medicine ER -