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[Sodium oxybutyrate and piracetam acceleration of the compensatory-reparative processes after damage to the cerebral cortex in rats].
Biull Eksp Biol Med. 1986 Dec; 102(12):661-3.BE

Abstract

The effects of sodium hydroxybutyrate and piracetam on compensatory-reparative processes in the central nervous system have been investigated in rats after extirpation of the frontal cortex. The animals were pretrained to conditioned reflex of active avoidance. Extirpation of the frontal cortex has been shown to disturb the conditioned reflex. Sodium hydroxybutyrate (50 mg/kg) and piracetam (200 mg/kg) were found to precipitate the recovery of the damaged reflexes.

Authors

Romanova GA
No affiliation info available
Trofimov SS
No affiliation info available

MeSH

AnimalsAvoidance LearningCerebral CortexCerebral DecorticationConditioning, ClassicalHydroxybutyratesMalePiracetamPyrrolidinonesRatsSodium OxybateTime Factors

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

3801613

Citation

Romanova, G A., and S S. Trofimov. "[Sodium Oxybutyrate and Piracetam Acceleration of the Compensatory-reparative Processes After Damage to the Cerebral Cortex in Rats]." Biulleten' Eksperimental'noi Biologii I Meditsiny, vol. 102, no. 12, 1986, pp. 661-3.
Romanova GA, Trofimov SS. [Sodium oxybutyrate and piracetam acceleration of the compensatory-reparative processes after damage to the cerebral cortex in rats]. Biull Eksp Biol Med. 1986;102(12):661-3.
Romanova, G. A., & Trofimov, S. S. (1986). [Sodium oxybutyrate and piracetam acceleration of the compensatory-reparative processes after damage to the cerebral cortex in rats]. Biulleten' Eksperimental'noi Biologii I Meditsiny, 102(12), 661-3.
Romanova GA, Trofimov SS. [Sodium Oxybutyrate and Piracetam Acceleration of the Compensatory-reparative Processes After Damage to the Cerebral Cortex in Rats]. Biull Eksp Biol Med. 1986;102(12):661-3. PubMed PMID: 3801613.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Sodium oxybutyrate and piracetam acceleration of the compensatory-reparative processes after damage to the cerebral cortex in rats]. AU - Romanova,G A, AU - Trofimov,S S, PY - 1986/12/1/pubmed PY - 1986/12/1/medline PY - 1986/12/1/entrez SP - 661 EP - 3 JF - Biulleten' eksperimental'noi biologii i meditsiny JO - Biull Eksp Biol Med VL - 102 IS - 12 N2 - The effects of sodium hydroxybutyrate and piracetam on compensatory-reparative processes in the central nervous system have been investigated in rats after extirpation of the frontal cortex. The animals were pretrained to conditioned reflex of active avoidance. Extirpation of the frontal cortex has been shown to disturb the conditioned reflex. Sodium hydroxybutyrate (50 mg/kg) and piracetam (200 mg/kg) were found to precipitate the recovery of the damaged reflexes. SN - 0365-9615 UR - https://www.unboundmedicine.com/medline/citation/3801613/[Sodium_oxybutyrate_and_piracetam_acceleration_of_the_compensatory_reparative_processes_after_damage_to_the_cerebral_cortex_in_rats]_ DB - PRIME DP - Unbound Medicine ER -