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Diffuse, progressive hyperpigmentation: an unusual skin manifestation of mycosis fungoides.
J Am Acad Dermatol. 1987 Jan; 16(1 Pt 2):257-60.JA

Abstract

Pigmentary changes in mycosis fungoides usually occur in association with poikiloderma atrophicans vasculare or following therapy and regression of lesions. Several cases of hypopigmented mycosis fungoides have also been reported. We present the case report of a patient who developed pruritic, diffuse macular hyperpigmentation of the skin. Biopsy specimens from hyperpigmented skin revealed histologic and ultrastructural features typical of mycosis fungoides. Giant melanin granules were found in the tumor cells, as well as in keratinocytes and Langerhans cells. As far as we know, this is the first report of cutaneous hyperpigmentation as a single presenting sign of mycosis fungoides.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3819062

Citation

David, M, et al. "Diffuse, Progressive Hyperpigmentation: an Unusual Skin Manifestation of Mycosis Fungoides." Journal of the American Academy of Dermatology, vol. 16, no. 1 Pt 2, 1987, pp. 257-60.
David M, Shanon A, Hazaz B, et al. Diffuse, progressive hyperpigmentation: an unusual skin manifestation of mycosis fungoides. J Am Acad Dermatol. 1987;16(1 Pt 2):257-60.
David, M., Shanon, A., Hazaz, B., & Sandbank, M. (1987). Diffuse, progressive hyperpigmentation: an unusual skin manifestation of mycosis fungoides. Journal of the American Academy of Dermatology, 16(1 Pt 2), 257-60.
David M, et al. Diffuse, Progressive Hyperpigmentation: an Unusual Skin Manifestation of Mycosis Fungoides. J Am Acad Dermatol. 1987;16(1 Pt 2):257-60. PubMed PMID: 3819062.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffuse, progressive hyperpigmentation: an unusual skin manifestation of mycosis fungoides. AU - David,M, AU - Shanon,A, AU - Hazaz,B, AU - Sandbank,M, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 257 EP - 60 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 16 IS - 1 Pt 2 N2 - Pigmentary changes in mycosis fungoides usually occur in association with poikiloderma atrophicans vasculare or following therapy and regression of lesions. Several cases of hypopigmented mycosis fungoides have also been reported. We present the case report of a patient who developed pruritic, diffuse macular hyperpigmentation of the skin. Biopsy specimens from hyperpigmented skin revealed histologic and ultrastructural features typical of mycosis fungoides. Giant melanin granules were found in the tumor cells, as well as in keratinocytes and Langerhans cells. As far as we know, this is the first report of cutaneous hyperpigmentation as a single presenting sign of mycosis fungoides. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/3819062/Diffuse_progressive_hyperpigmentation:_an_unusual_skin_manifestation_of_mycosis_fungoides_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190-9622(87)80076-2 DB - PRIME DP - Unbound Medicine ER -